Bosch-Morell, FranciscoVillagrasa Sebastián, VictoriaOrtega Hernández-Agero, María TeresaAcero De Mesa, NuriaMuñoz-Mingarro, María DoloresGonzález Rosende, EugeniaCastillo García, EncarnaSanhauja Santafé, María AmparoSoriano Guarinos, PilarMartínez-Solís, Isabel2024-02-082024-02-082020'Bosch-Morell F, Villagrasa V, Ortega T, Acero N, Muñoz-Mingarro D, González-Rosende ME, Castillo E, Sanahuja MA, Soriano P, Martínez-Solís I. Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration. Neural Regen Res. 2020 Dec;15(12):2207-2216'1673-537410.4103/1673-5374.284978https://hdl.handle.net/20.500.14352/100298The retina may suffer neurodegenerative damages, as other tissues of the central nervous system do, and serious eye diseases may develop. One of them is age-related macular degeneration, which causes progressive loss of vision due to retina degeneration. Treatment of age-related macular degeneration focuses on antioxidant agents and anti-vascular endothelial growth factor compounds, among others, that prevent/diminish oxidative stress and reduce neovascularisation respectively. The phytochemicals, medicinal plants and/or plant-diet supplements might be a useful adjunct in prevention or treatment of age-related macular degeneration owing to their antioxidant and anti-vascular endothelial growth factor properties. This review article presents the most investigated plants and natural products in relation to age-related macular degeneration, such as saffron, ginkgo, bilberry and blueberry, curcuma or turmeric, carotenoids, polyphenols, and vitamins C and E. This study provides up-to-date information on the effects, treatments, safety and efficiency of these phytotherapy products.engAttribution-NonCommercial-ShareAlike 4.0 Internationalhttps://creativecommons.org/licenses/by-nc-sa/4.0/Medicinal plants and natural products as neuroprotective agents in age-related macular degenerationjournal article1876-7958https://doi.org/10.4103/1673-5374.284978open access615.01/.03Age-related macular degenerationBilberryBlueberryCurcumaCarotenoidsGinkgoPolyphenolsFarmacología (Farmacia)3209.07 Fitofármacos