Picazo González, Rosa AnaRojo Salvador, ConcepciónRodríguez Quirós, JesúsGonzález Gil, Alfredo2024-05-292024-05-292024-04-30Picazo, R.A.; Rojo, C.; Rodriguez-Quiros, J.; González-Gil, A. Current Advances in Mesenchymal Stem Cell Therapies Applied to Wounds and Skin, Eye, and Neuromuscular Diseases in Companion Animals. Animals 2024, 14, 1363. https://doi.org/10.3390/ ani140913632076-261510.3390/ani14091363https://hdl.handle.net/20.500.14352/1045532024 Descuento MDPIMesenchymal stem cells (MSCs) are considered a very promising alternative tool in cell therapies and regenerative medicine due to their ease of obtaining from various tissues and their ability to differentiate into different cell types. This manuscript provides a review of current knowledge on the use of MSC-based therapies as an alternative for certain common pathologies in dogs and cats where conventional treatments are ineffective. The aim of this review is to assist clinical veterinarians in making decisions about the suitability of each protocol from a clinical perspective, rather than focusing solely on research. MSC-based therapies have shown promising results in certain pathologies, such as spinal cord injuries, wounds, and skin and eye diseases. However, the effectiveness of these cell therapies can be influenced by a wide array of factors, leading to varying outcomes. Future research will focus on designing protocols and methodologies that allow more precise and effective MSC treatments for each case.Simple Summary: The search for alternative treatments is necessary for diseases where conventional therapies are ineffective. In recent years, therapies using mesenchymal stem cells have emerged as one of the most appropriate alternatives in regenerative medicine. Therapy with these types of cells is progressively increasing as a therapeutic option in veterinary medicine, leading to significant advances in treating certain pathologies. This review summarizes the current knowledge on mesenchymal stem cell therapies and their potential therapeutic and clinical effects on wound and skin, ocular, and neuromuscular diseases in dogs and cats.engAttribution 4.0 Internationaljournal articlehttps://doi.org/10.3390/ani1409136338731367https://www.mdpi.com/journal/animalsopen access636.09Mesenchymal stem cellsCell therapySpinal cord injuryWoundSkin diseaseEye diseaseDogsCatsVeterinaria3109 Ciencias Veterinarias