Ortega Rodríguez, AliciaShen, YingliZabala Gutiérrez, IreneSantos, Harrison D. A.Torres Vera, Vivian AndreaXimedes, ErvingVillaverde Cantizano, GonzaloLifante, JoséGerke, ChristophFernández Monsalve, NuriaGómez Calderón, ÓscarMelle Hernández, SoniaMarqués Hueso, JoséMéndez González, DiegoLaurenti, MarcoJones, Callum M. S.López Romero, Juan ManuelContreras Cáceres, RafaelJaque García, DanielRubio Retama, Benito JorgeGarma Pons, Santiago2023-06-162023-06-162020-02-18Ortega Rodríguez, A., Shen, Y., Zabala gutiérrez, I., et al. «10-Fold Quantum Yield Improvement of Ag 2 S Nanoparticles by Fine Compositional Tuning». ACS Applied Materials & Interfaces, vol. 12, n.o 11, marzo de 2020, pp. 12500-09. DOI.org (Crossref), https://doi.org/10.1021/acsami.9b22827.1944-824410.1021/acsami.9b22827https://hdl.handle.net/20.500.14352/6125Ag2S semiconductor nanoparticles (NPs) are near-infrared luminescent probes with outstanding properties (good biocompatibility, optimum spectral operation range, and easy biofunctionalization) that make them ideal probes for in vivo imaging. Ag2S NPs have, indeed, made possible amazing challenges including in vivo brain imaging and advanced diagnosis of the cardiovascular system. Despite the continuous redesign of synthesis routes, the emission quantum yield (QY) of Ag2S NPs is typically below 0.2%. This leads to a low luminescent brightness that avoids their translation into the clinics. In this work, an innovative synthetic methodology that permits a 10-fold increment in the absolute QY from 0.2 up to 2.3% is presented. Such an increment in the QY is accompanied by an enlargement of photoluminescence lifetimes from 184 to 1200 ns. The optimized synthetic route presented here is based on a fine control over both the Ag core and the Ag/S ratio within the NPs. Such control reduces the density of structural defects and decreases the nonradiative pathways. In addition, we demonstrate that the superior performance of the Ag2S NPs allows for high-contrast in vivo bioimaging. .engjournal article1944-8252https://dx.doi.org/10.1021/acsami.9b22827https://pubs.acs.org/doi/abs/10.1021/acsami.9b22827#open access616-07539.2:620.1543.4Ag2S/AgNanoparticlesFluorescence probesSynthesis optmizationPL lifetimeNIR-II imagingÓptica (Física)Óptica geométrica e instrumentalTécnicas de la imagen2209.19 Óptica Física2209.06 Óptica geométrica