Fernández Aceñero, María JesúsMartinez Useros, JDíez Valladares, Luis IgnacioGarcía Botella, Alejandra MaríaOrtega Medina, LuisPérez Aguirre, María EliaDe la-Serna Esteban, Sofía CristinaLatorre, ENeelsen, L2026-01-132026-01-132019-06-241699-048Xhttps://hdl.handle.net/20.500.14352/130078IntroductionOur aim is to find features that define prognosis in surgically resected ductal pancreatic adenocarcinoma readily accessible in everyday practice.Materials and methodsLongitudinal retrospective case series of pancreatic adenocarcinoma operated with a curative intent in a large tertiary hospital in Madrid between 2009 and 2015.Results162 were enrolled. 40.8% survived less than 1year. Multivariate Cox's regression model revealed that gender, presence of symptoms, T and N stage independently influenced progression-free survival, while overall survival was determined by gender, smoking, presence of symptoms and N stage. Logistic regression analysis revealed that only symptoms at diagnosis could predict death, while gender, symptoms, histopathological type, vessel invasion, T stage and necrosis could independently predict recurrence.DiscussionOur series show that patients with symptomatic disease at the time of diagnosis and females showed a shorter progression-free and overall survival. We herein propose a regression model to predict outcome.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Still a place for conventional histopathological analysis in the era of molecular medicine: predicting prognosis of resectable ductal pancreatic adenocarcinomajournal articlehttps://doi.org/10.1007/s12094-018-02008-4https://link.springer.com/article/10.1007/s12094-018-02008-4restricted access611.018AdenocarcinomaPancreasPrognosisSurgical therapyCiencias Biomédicas32 Ciencias Médicas