Smirnov, AntonYanushevich, OlegKrikheli, NatellaSolis Pinargote, Nestor WashingtonPeretyagin, PavelGrigoriev, SergeyAlou Cervera, LuisSevillano Fernández, DavidLópez Piriz, RobertoGuitian, FranciscoBartolomé Gómez, José FlorindoVaroni, Elena2024-05-242024-05-242024-02-09Smirnov A, Yanushevich O, Krikheli N, Solis Pinargote NW, Peretyagin P, Grigoriev S, Alou L, Sevillano D, López-Piriz R, Guitian F, et al. 3Y-TZP/Ta Biocermet as a Dental Material: An Analysis of the In Vitro Adherence of Streptococcus Oralis Biofilm and an In Vivo Pilot Study in Dogs. Antibiotics. 2024; 13(2):175. https://doi.org/10.3390/antibiotics130201752079-638210.3390/antibiotics13020175https://hdl.handle.net/20.500.14352/104406The surface adhesion of bacterial cells and the in vivo biocompatibility of a new ceramic–metal composite made of zirconium dioxide and tantalum were evaluated. Within the framework of an in vitro study using the crystal violet staining and colony counting methods, a relatively similar adhesion of Streptococcus oralis to the 3Y-TZP/Ta biocermet (roughness Ra = 0.12 ± 0.04 µm) and Ti-Al6-V4 titanium alloy (Ra = 0.04 ± 0.01 µm) was found. In addition, in an in vivo preliminary study focused on the histological analysis of a series of rods implanted in the jaws of beagle dogs for a six-month period, the absence of any fibrous tissue or inflammatory reaction at the interface between the implanted 3Y-TZP/Ta biocermets and the new bone was found. Thus, it can be concluded that the developed ceramic–metal biocomposite may be a promising new material for use in dentistry.engAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/journal articlehttps://doi.org/10.3390/antibiotics1302017538391561https://www.mdpi.com/2079-6382/13/2/175open access579.2ZirconiaTantalumCeramic–metal compositesImplantsStreptococcus oralisBiofilmBone growthMicrobiología médica2414 Microbiología