Fraile Fernández, AndrésFuertes Recuero, ManuelEspinel Rupérez, JorgeCárdenas Osuna, AlejandroRuano Barreda, RicardoHorcajada Garcia, JavierOrtiz Díez, Gustavo2025-03-282025-03-282025Fraile-Fernandez, A., Fuertes-Recuero, M., Espinel-Rupérez, J., Cárdenas-Osuna, A., Barreda, R. R., Horcajada-Garcia, J., & Ortiz-Diez, G. (2025). Reconstruction of a rostral maxillary defect by two custom-made titanium implants following a partial maxillectomy for treatment of squamous cell carcinoma in a dog. Veterinary research communications, 49(2), 80. https://doi.org/10.1007/s11259-025-10643-w0165-738010.1007/s11259-025-10643-whttps://hdl.handle.net/20.500.14352/119030Author contributions: All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by MFR, AFF, JER, ACO, RRB, JHG, and GOD. The first draft of the manuscript was written by MFR, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.This case report describes the reconstruction of a rostral maxillary defect by two custom-made titanium implants following a rostral partial maxillectomy for treatment of squamous cell carcinoma (SCC) in a seven-year-old dog. An incisional biopsy and CT scan were performed to establish the diagnosis, to plan possible surgery, and to assess the margins of the tumour. The patient had no radiographic signs of metastasis at the time of diagnosis. An oblique rostral partial maxillectomy with two custom-made titanium plates was chosen as an effective oncological treatment and to maintain the cosmetic appearance. A first custom implant was designed to support the cheek and lips, and a second implant was designed to replace part of the hard palate and serve as a base for the palatal mucosal flap. Surgical treatment combined with toceranib phosphate and cimicoxib therapy provided a survival time of at least 1700 days, as the patient is still alive at time of publication. Further research is warranted to determine the oncological and cosmetic efficacy of this surgical technique for treatment of SCC in a larger group of dogsengjournal article1573-7446https://doi.org/10.1007/s11259-025-10643-w39820619restricted access619:617-089Custom-made surgical prothesisOral tumoursSurgeryTitanium platesVeterinariaCirugía bucofacial3109 Ciencias Veterinarias3109.10 Cirugía