Ferreira González, FernandaCaponio,Vito Carlo AlbertoLópez-Pintor Muñoz, Rosa MaríaKemcha,NardjesseTorres García Denche, JesúsLeco Berrocal, María Isabel2025-11-252025-11-252025-03Ferreira González F, Caponio VCA, López-Pintor RM, Kemcha N, Torres J, Leco Berrocal I. Effectiveness of low-level diode laser in the management of complications after third-molar surgical extraction: Systematic review and meta-analysis. J Am Dent Assoc. 2025 Mar;156(3):211-224.e11. doi: 10.1016/j.adaj.2024.12.0080002-817710.1016/j.adaj.2024.12.00839903156https://hdl.handle.net/20.500.14352/126492Background: The aim of this study was to evaluate the effects of low-level laser therapy (LLLT) in reducing postoperative pain, swelling, and trismus after extraction of third molars. Types of studies reviewed: The authors conducted a literature search without restriction on dates or language in the following databases: PubMed (MEDLINE), Cochrane Central Register of Controlled Trials database, Web of Science, and Scopus. They selected only split-mouth randomized clinical trials investigating the use of LLLT and comparing the effectiveness with a placebo group. Results: The authors identified 803 references and evaluated 131 articles in full text. After this analysis, the authors included 18 articles in this study. The results of the meta-analysis suggest potential efficacy of LLLT in the reduction of postoperative pain (standardized mean difference [SMD], -1.11; 95% CI, -1.63 to -0.58; P < .001) and swelling (SMD, -0.50; 95% CI, -0.88 to -0.11; P = .01) at 48 hours and trismus (SMD, 0.35; 95% CI, 0.16 to 0.53; P = .002) at 7 days after surgery. Practical implications: Evidence shows low certainty to indicate the use of LLLT after mandibular third-molar extraction. Future studies with improved methodology are needed to establish its efficacy in reducing pain, swelling, and trismusengjournal article1943-4723https://doi.org/10.1016/j.adaj.2024.12.008https://www.sciencedirect.com/science/article/pii/S000281772400713X?via%3Dihubhttps://pubmed.ncbi.nlm.nih.gov/39903156/restricted access616.314-089:615.849.19Oral surgeryThird molarsDiode laserLow-level laser therapyPostoperative painSystematic reviewOdontología (Odontología)Cirugía bucofacialLáseresAparatos y material odontológicos3201 Ciencias Clínicas3213 Cirugía2209.10 láseres3311.03 Instrumentos Para Odontología