Guzmán Aránguez, Ana IsabelFonseca Vázquez, BegoñaCarracedo Rodríguez, Juan GonzaloMartín Gil, AlbaMartínez Águila, AlejandroPintor Just, Jesús Jerónimo2023-06-172023-06-172016-09Guzman Aranguez, A. I., Fonseca Vázquez, B., Carracedo Rodríguez, J. G. et al. «Dry Eye Treatment Based on Contact Lens Drug Delivery: A Review». Eye & Contact Lens: Science & Clinical Practice, vol. 42, n.o 5, septiembre de 2016, pp. 280-88. DOI.org (Crossref), https://doi.org/10.1097/ICL.0000000000000184.1542-232110.1097/ICL.0000000000000184https://hdl.handle.net/20.500.14352/17626Dry eye disease affects a substantial segment of the word population with increasing frequency. It is a multifactorial disease of the ocular surface and tear film, which causes ocular discomfort, visual disturbances, and tear instability with potential damage to the cornea and conjunctiva. Because of its multifactorial etiology, the use of different pharmacological treatment for dry eye treatment has been proposed, which include anti-inflammatory molecules, lubricants or comfort agents, and secretagogues. However, in some cases these pharmacological approaches only relieve symptoms temporarily, and consequently, eye care professionals continue to have difficulties managing dry eye. To improve pharmacological therapy that allows a more efficient and long-term action, effective ocular drug delivery of the currently available drugs for dry eye treatment is required. Contact lenses are emerging as alternative ophthalmic drugs delivery systems that provide an increased residence time of the drug at the eye, thus leading to enhanced bioavailability and more convenient and efficacious therapy. In this article, we reviewed the different techniques used to prepare contact lens-based drug delivery systems and focused on articles that describe the delivery of compounds for dry eye treatment through contact lenses.engjournal articlehttp://dx.doi.org/10.1097/ICL.0000000000000184restricted access617.7-089.243617.764Dry eyeDrug deliveryOcular surfaceContact lensesBioquímica (Química)OftalmologíaLentes de contacto3201.09 Oftalmología3311.11 Instrumentos ópticos