García Esteban, María TeresaPelaz, Carmen2025-10-282025-10-282008-02-26García, & Pelaz. (2008). Effectiveness of disinfectants used in cooling towers against Legionella pneumophila. Chemotherapy, 54(2), 107-116. https://doi.org/10.1159/0001186620009-315710.1159/000118662https://hdl.handle.net/20.500.14352/125470Background: Legionella persists in man-made aquatic installations despite preventive treatments. More information about disinfectants could improve the effectiveness of treatments. This study tests the susceptibility of Legionella pneumophila serogroup (sg) 1 against 8 disinfectants used in cooling tower treatments. Methods: We determined the minimal inhibitory concentration (MIC), minimal bactericidal concentration (MBC) and bactericidal effect of sodium hypochlorite (A), hydrogen peroxide with silver nitrate (B), didecyldimethylammonium chloride (C), benzalkonium chloride (D), tributyltetradecylphosphonium chloride (E), tetrahydroxymethylphosphonium sulfide (F), 2,2-dibromonitropropionamide (G) and chloromethylisothiazolone (H) against 28 L. pneumophila sg 1 isolates. Results: MIC and MBC values were equivalent. Bacteria are less susceptible to disinfectants F, B, D and A than to H, E, C and G. All disinfectants induced a bactericidal effect. The effect rate is dose dependent for G, H, F and B; the effect is fast for the rest of disinfectants at any concentration. The bactericidal activity of disinfectants A, G and F depends on the susceptibility test used. Conclusions: All disinfectants have bactericidal activity against L. pneumophila sg 1 at concentrations used in cooling tower treatments. Results depend on the assay for some products.engEffectiveness of disinfectants used in cooling towers against Legionella pneumophilajournal article1421-9794https://doi.org/10.1159/000118662https://karger.com/che/article/54/2/107/66271/Effectiveness-of-Disinfectants-Used-in-Cooling?searchresult=1restricted access579.61621.56615.28616.9DisinfectantsLegionellaBactericidal effectInhibitory-bactericidal activityMicrobiología (Biología)Enfermedades infecciosas2414 Microbiología3313.26 Equipo de Refrigeración2302.20 Química Microbiológica3205.05 Enfermedades Infecciosas