Gutiérrez López, RafaelMartínez de la Puente, JosuéGangoso De La Colina, Laura EstherSoriguer, RamónFiguerola, Jordi2024-11-272024-11-272020Gutiérrez-López, R., Martínez-de la Puente, J., Gangoso, L., Soriguer, R., & Figuerola, J. (2020). Plasmodium transmission differs between mosquito species and parasite lineages. Parasitology, 147(4), 441–447. doi:10.1017/S00311820200000620031-182010.1017/s0031182020000062https://hdl.handle.net/20.500.14352/111158This study was funded by projects CGL2015-65055-P and PGC2018-095704-B-100 from the Spanish Ministry of Science, Innovation and Universities and from the European Regional Development Fund (FEDER). RGL was supported by a FPI grant (BES-2013-065274). JMP was partially supported by a 2017 Leonardo Grant for Researchers and Cultural Creators, BBVA Foundation. The Foundation accepts no responsibility for the opinions, statements and contents included in the project and/or the results thereof, which are entirely the responsibility of the authors. LG was supported by a Marie Sklodowska-Curie Fellowship of the European Commission (grant number 747729 ‘EcoEvoClim’). Fieldwork facilities were provided by Doñana ICTS-RBD.Factors such as the particular combination of parasite–mosquito species, their co-evolutionary history and the host's parasite load greatly affect parasite transmission. However, the importance of these factors in the epidemiology of mosquito-borne parasites, such as avian malaria parasites, is largely unknown. Here, we assessed the competence of two mosquito species [Culex pipiens and Aedes (Ochlerotatus) caspius], for the transmission of four avian Plasmodium lineages (Plasmodium relictum SGS1 and GRW11 and Plasmodium cathemerium-related lineages COLL1 and PADOM01) naturally infecting wild house sparrows. We assessed the effects of parasite identity and parasite load on Plasmodium transmission risk through its effects on the transmission rate and mosquito survival. We found that Cx. pipiens was able to transmit the four Plasmodium lineages, while Ae. caspius was unable to transmit any of them. However, Cx. pipiens mosquitoes fed on birds infected by P. relictum showed a lower survival and transmission rate than those fed on birds infected by parasites related to P. cathemerium. Non-significant associations were found with the host–parasite load. Our results confirm the existence of inter- and intra-specific differences in the ability of Plasmodium lineages to develop in mosquito species and their effects on the survival of mosquitoes that result in important differences in the transmission risk of the different avian malaria parasite lineages studied.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/journal article1469-8161https://doi.org/10.1017/S0031182020000062https://www.cambridge.org/core/journals/parasitology/article/plasmodium-transmission-differs-between-mosquito-species-and-parasite-lineages/7A71241F6C95735ADC486D6098AA53E9open access616.936576.89595.771616-036.22Avian malaria parasitesHost–parasite interactionsMosquitoesVector-borne pathogensVector-competenceParasitología (Medicina)AvesEcología (Biología)2401.12 Parasitología Animal2401.20 Ornitología2401.06 Ecología Animal3202 Epidemiología