Tirado Armesto, Diego FelipeCalvo Garrido, María Lourdes2023-06-172023-06-172019Tirado, Diego F., y Lourdes Calvo. «The Hansen Theory to Choose the Best Cosolvent for Supercritical CO2 Extraction of β-Carotene from Dunaliella Salina». The Journal of Supercritical Fluids, vol. 145, marzo de 2019, pp. 211-18. DOI.org (Crossref), https://doi.org/10.1016/j.supflu.2018.12.013.0896-844610.1016/j.supflu.2018.12.013https://hdl.handle.net/20.500.14352/12898The Hansen solubility theory was used to predict the best cosolvent for supercritical carbon dioxide (sc-CO2) to achieve the selective extraction of β-carotene from Dunaliella salina. Among four organic cosolvents, ethanol was predicted to be the best based on minima Ra values. The predictions were validated through equilibrium data and extraction curves from the microalgae. The addition of ethanol reduced the bubble pressures, and therefore increased the solubility of the β-carotene. With 5% mass fraction, at 318.15 K and 20 MPa, the extraction yield was 25 g carotenoids kg microalgae−1, much more than in pure sc-CO2 (6 g).engAttribution-NonCommercial-NoDerivatives 4.0 Internationaljournal articlehttps://doi.org/10.1016/j.supflu.2018.12.013open access66.0620Hansen solubility parametersFood-grade ingredientsSupercritical fluid extractionCosolvent effectCarotenoidsMicroalgaeQuímicaIngeniería químicaMateriales23 Química3303 Ingeniería y Tecnología Químicas3312 Tecnología de Materiales