Person:
Burgueño Torres, Laura

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First Name
Laura
Last Name
Burgueño Torres
URI
https://hdl.handle.net/20.500.14352/79799
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Odontología
Department
Especialidades Clínicas Odontológicas
Area
Estomatología
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2023 - 20243
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    Analysis of craniocervical abnormalities in osteogenesis imperfecta during growth
    (Applied Sciences, 2024) Nova García, Manuel Joaquín De; García de Sola, Rafael; Burgueño Torres, Laura
    Osteogenesis Imperfecta (OI) is a genetic disease characterized by osteopenia and bone fragility in which the craniocervical junction is also affected. This is of special relevance due to the high prevalence in anomalies described in the literature as follows: basilar invagination, basilar impression, and platybasia. Methods. We analyzed 19 lateral skull radiographs and 14 magnetic resonance images (MRIs) of 28 patients with OI in which eight linear and five angular measurements were plotted to determine the existence of craniocervical junction anomalies and compare them with 38 lateral skull radiographs and 28 MRIs performed on age-matched healthy controls. Results. From the reference values obtained from the control sample for each age group, we established the limit value at which pathology could be suspected. Some of the variables studied showed a clear trend associated with growth. More than half of the patients (60.71%) presented an anomaly in the skull base. Conclusions. According to the diagnostic criteria used and taking +2.5 SD as the limit value, 10.71% of the patients had basilar invagination, 35.71% had basilar impression, and 39.29% had platybasia, the latter being the most common finding
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    Application of orthopantomography in the analysis of bone mineral density in patients with osteogenesis imperfecta
    (Applied Sciences, 2024) García Boedo, Lara; Burgueño Torres, Laura; Nova García, Manuel Joaquín De
    Osteogenesis imperfecta is a disorder characterized by osteopenia and bone fragility. Con sidering that orthopantomography is a routine diagnostic test in growing patients, it can be used to analyze bone density in these patients. The study sample consisted of 21 child patients diagnosed with OI, under medical treatment with antiresorptives and for whom orthopantomography was available, analyzed and compared with 20 healthy children. The panoramic radiographs were ana lyzed and the radiomorphometric indices and fractal dimension were measured after first selecting the areas of interest to be studied. The results showed that fractal dimension of the basal cortical bone was lower in the study group, and MCW was lower in patients with osteogenesis imperfecta. In addition, MCW and fractal dimension were lower with higher number of treatment cycles re ceived. In light of the results obtained, we can conclude that panoramic radiography can be useful in analyzing changes in bone mineral density in these patients throughout the course of treatment.
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    Influence of the severity of osteogenesis imperfecta on cranial measurements
    (Children, 2023) Nova García, Manuel Joaquín De; García de Sola, Rafael; Burgueño Torres, Laura
    Osteogenesis Imperfecta (OI) is a disease that causes bone fragility and deformities, affecting both the cranial base and the craniocervical junction, and may lead to other neurological disorders. A retrospective cross-sectional study was carried out based on cephalometric analysis of the cranial base in a sample of patients with OI, in lateral skull radiographs and magnetic resonance imaging (MRI), comparing them with a sample of age-matched controls. When the different variables of the craniocervical junction were analyzed, significance was found in comparisons with the different age groups. All measurements of the variables studied stabilized as growth progressed. For most of the variables, the severity of the disease influences the measurements of the skull base, with statistically significant differences. Both age and severity of the disease are factors that directly influence the anatomy of the craniocervical junction in these patients and may serve as indicators in the early detection and prevention of other derived alterations.