Person: Manso Díaz, Gabriel
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First Name
Gabriel
Last Name
Manso Díaz
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Veterinaria
Department
Medicina y Cirugía Animal
Area
Medicina y Cirugía Animal
Identifiers
13 results
Search Results
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Item 18F-sodium fluoride positron emission tomography provides pertinent additional information to computed tomography for assessment and management of tarsal pain in horses(Journal of the American Veterinary Medical Association, 2023) Espinosa Mur, Pablo; Spriet, Mathieu; Manso Díaz, Gabriel; Arndt, Stefanie; Pérez Nogues, Marcos; López San Román, Francisco Javier; García Mata, Ricardo; Katzman, Scott A.; Galuppo, Larry D.Objective: To assess the value of F-sodium fluoride (18F-NaF) positron emission tomography (PET) for imaging the tarsus and proximal metatarsus and compare it with CT and lameness evaluation. Animals: 25 horses with lameness localized to the tarsal and proximal metatarsal regions that underwent 18F-NaF PET/CT between 2016 and 2021. Methods: 18F-NaF PET and CT images were retrospectively independently evaluated by 3 observers. Standardized uptake values (SUV) were used to characterize 18F-NaF uptake. Correlation between PET and CT findings with subjective and objective maximum (Max-D) and minimum pelvic height lameness data was estimated. Results: The inter-observer Kappa-weighted value (κ) was higher for PET (κ = 0.66) than CT (κ = 0.6). CT and PET scores were fairly correlated (R = 0.49; P < 0.05). PET SUVratio (SUV of the main lesion/SUV talus) had the highest correlation with Max-D (R = 0.71; P < .05). PET and CT scores for the plantar region were significantly higher in Quarter Horses (P < .05) and showed consistently higher correlation with objective lameness data (CT plantar grade - Max-D [R = 0.6; P < .05], PET plantar grade - Max-D [R = 0.47; P = .04]) than other regions of the distal tarsal joints. Three Warmbloods presented marked uptake at the medial cochlea of the distal tibia. Clinical Relevance: PET had a moderate correlation with CT for assessment of tarsal lesions. The degree of PET uptake can help differentiate active versus inactive lesions. Specific location of the uptake is important in determining clinical relevance.- Project number: 96
Item Atlas QR de procedimientos básicos en clínica hospitalaria equina(2018) López San Román, Francisco Javier; Fores Jackson, Paloma; Manso Díaz, Gabriel; Varela Del Arco, Marta; Troya Portillo, Lucas; Santiago Llorente, Isabel; Martín Espada, María Del Carmen; Rocha Lopesino, Luis Alberto de la; López Abradelo, PatriciaLos códigos QR se utilizan actualmente como herramienta docente de gran utilidad ya que permiten al alumno emplear las nuevas tecnologías para el aprendizaje. Con este proyecto pretendemos acercar la actividad clínica equina al alumno de veterinaria. Item Correlation between kinematic parameters, ataxia and ground-to-lip distance in detomidine sedated horses(Equine Veterinary Journal, 2024) Izquierdo Moreno, Jorge; Illán de Paz, Marta; Manso Díaz, Gabriel; Villalba Orero, María; López San Román, Francisco JavierBackground An accurate evaluation of the degree of sedation is mandatory to adjust the dosage of sedative drugs. Objectives To determine the correlation between head height above the ground and ataxia degree in horses sedated with detomidine and the correlation existing between accelerometric variables and both parameters. Study design Retrospective study. Methods Twelve horses were given 0.01 mg/kg of detomidine hydrochloride iv. Measured accelerometric parameters, with one accelerometer positioned between both sacral tuberosities, included speed, stride frequency and length, regularity, dorsoventral, longitudinal, mediolateral and total accelerometric activities, relative force index and dorsoventral, longitudinal and mediolateral parts of the accelerometric activities. Head height above the ground (cm) and subjective ataxia degree were also measured. Baseline values (−15 min) and values measured 5 and 15 min after the injection and then every 15 min for a period of 2 h were obtained. Results There was a negative and strong correlation between head height above the ground and ataxia degree (Pearson r = −0.78, p < 0.001), particularly during the first 45 min. A significant correlation was found between head height above the ground and almost all accelerometric parameters. This correlation was very strong with stride frequency, regularity and dorsoventral and total accelerometric activities in both cases, but for ataxia, also with total accelerometric activity. Main limitations Experimental conditions may not represent real clinical situations. Conclusions Stride frequency and regularity are the most reliable parameters to determine degree of sedation and are related to the sedation produced. Ataxia should not be considered a separate property of sedation and does not need to be assessed separately to the depth of sedationItem Magnetic resonance dacryocystography in the horse: A feasibility study(Veterinary Ophthalmology, 2019) Manso Díaz, Gabriel; García-López, J.M.; López San Román, Francisco Javier; Taeymans, O.Objective: To provide a comprehensive anatomical description of the normal equine nasolacrimal duct using magnetic resonance imaging, and to develop a practical protocol for performing magnetic resonance dacryocystography (MRD) in horses. Animal studied: The heads of ten fresh horse cadavers with no history of sinonasal or ophthalmologic disorders were used for this study. Procedure: An MRD technique was developed in this study, which consisted of two parts. In the first part, olive oil and gadolinium were compared as contrast medium, using five horses. Two concentrations of gadolinium were used: 0.25 mmol/mL and 0.5 mmol/mL. In the second part, the influence of different head recumbencies using olive oil as the sole contrast medium was studied in the remaining five horses. Results: Injection with olive oil resulted in better distention and a complete filling of the nasolacrimal duct (ND) in all horses. Injection of 0.25 mmol/mL of gadolinium resulted in incomplete filling of the ND, whereas injection of 0.5 mmol/mL of gadolinium resulted in slightly better filling of the duct. The nondependent duct showed better distention compared to the dependent duct when scanning in lateral recumbency. No differences were observed between ducts in a dorsal recumbency. The degree of distention in dorsal recumbency was slightly less than the degree of distention observed in the nondependent ND in lateral recumbency. Conclusions: Magnetic resonance dacryocystography is a suitable technique for evaluating the nasolacrimal duct and can be performed during a normal magnetic resonance examination.- Project number: 224
Item Desarrollo de simuladores no virtuales en la docencia de la clínica equina(2020) López San Román, Francisco Javier; Manso Díaz, Gabriel; Villalba Orero, María; Jiménez Tabasco, Alberto; Sanz Dueñas, Javier; Santiago Llorente, Isabel; Sefrioui Khamali, Zouhair; Varela Del Arco, Marta; Velasco Matesanz, Laura; Martínez Sánchez, MercedesEl proyecto actual se ha centrado en el desarrollo de modelos no virtuales. La adquisición de habilidades prácticas sigue diferentes pasos en la curva de aprendizaje y, para ello, es necesario partir de un conocimiento de las bases teóricas y observar previamente el procedimiento. Sin embargo, el alumno debe de llevar a cabo el procedimiento por si mismo. En la actualidad esto se realiza con cadáveres y animales vivos, lo cual está limitado por el cada vez más complicado acceso a los primeros y la estricta normativa vigente sobre bienestar animal. Por esta razón, hemos pretendido crear simuladores que suplan las limitaciones actuales. De tal manera, hemos comenzado con la creación de un modelo de artroscopia equina con la articulación radiocarpiana que facilite, por un lado, el entendimiento de la anatomía artroscopia de las articulaciones equinas y, por otro lado, el desarrollo de sus habilidades prácticas. - Project number: 135
Item Atlas de endoscopia de las vías respiratorias del caballo(2016) Fores Jackson, Paloma; López San Román, Francisco Javier; Manso Díaz, Gabriel; Herrán Vilella, Ramón Cayetano; Santiago Llorente, Isabel; Goyoaga Elizalde, Jaime; Ezquerra Calvo, Luis Javier; García López, José MªLa endoscopia es una técnica diagnóstica y terapéutica, mínimamente invasiva, imprescindible para la clínica equina. Pero además, es una técnica, que al ser altamente visual, es perfecta para fijar y mejorar los conocimientos de anatomía, fisiología y patología, en nuestro caso en concreto, de las vías respiratorias del caballo. Este atlas contiene información básica sobre los aspectos técnicos de la endoscopia respiratoria del caballo y los principales hallazgos fisiológicos y patológicos de la misma. Item Morphine with or without Acepromazine in Horses: A Kinematic Evaluation(Animals, 2022) López San Román, Francisco Javier; Montes Freilich, Gloria; Gómez Cisneros, David; Izquierdo Moreno, José; Varela Del Arco, María; Manso Díaz, GabrielMorphine is an opioid agonist drug and produces a significant analgesic effect in horses but besides the evidenced analgesic effect, the use of morphine is not routine due to the potential excitatory effects described in the literature. To minimize these effects, neuroleptanalgesia, or the combination of opioids and sedative drugs, is encouraged. Our aim was to describe changes occurring in the locomotor pattern after co-administration of a tranquilizer, acepromazine, and morphine in horses. Six mature horses were used and received four different treatments with saline solution, morphine, acepromazine, or a combination of morphine and acepromazine. A three-dimensional accelerometric device was used to collect data and objectivize those findings moreover the sedative effect of the treatments was also measured. Significant differences were observed when comparing all the treatments in the majority of accelerometric variables, except the regularity of the pattern, some energetic parameters, and tranquilization. An evident counteraction of the effects caused by both morphine and acepromazine was observed. Due to these effects, the possibility of adding acepromazine to an additional analgesic treatment with morphine in the clinical setting ensures the absence of the supplemental instability caused by other sedatives and minimizes the potential opioid excitatory effects.Item Ultrasonographic visualisation of the mesenteric vasculature in horses with large colon colic(Veterinary Record, 2020) Manso Díaz, Gabriel; David M Bolt; López San Román, Francisco JavierBackground: Ultrasonographic visualisation of the mesenteric vasculature of the large colon (LC) from the right side of the abdomen in cases of displacement and volvulus has been described. However, the LC can move freely within the abdomen and its mesentery can potentially contact both sides of the abdominal wall. Methods: Thirty-four horses presented with LC-related colic that had visible LC mesenteric vasculature visible on abdominal ultrasound were included. A control group was made including horses with confirmed small intestinal-related colic. The objective of this study was to evaluate the visibility of LC mesenteric vasculature with transabdominal ultrasonography in horses with LC-related colic and to determine its diagnostic value. Results: The LC mesenteric vasculature was identified on the right side of the abdomen in 16/34 horses with right dorsal displacement of the LC (RDDLC), 180° LC volvulus (LCV), 540° LCV or LC impaction. On the left side of the abdomen, LC mesenteric vessels were identified in 17/34 horses with left dorsal displacement of the LC (LDDLC), 180° LCV or RDDLC. Vessels were visualised on both sides in one horse with a 180° LCV. Presence of LC mesenteric vasculature in the dorsal aspect on the left side of the abdomen was significantly associated with LDDLC. Conclusion: LC mesenteric vasculature can be visualised on transabdominal ultrasound from either side of the abdomen in horses with different forms of LC-related colic.- Project number: 324
Item Exploración radiográfica del caballo: bases técnicas y atlas interactivo(2015) García Real, María Isabel; Manso Díaz, Gabriel; López San Román, Francisco Javier; Goyoaga Elizalde, Jaime; Herrán Vilella, Ramón Cayetano Item Treatments and Prognosis for Subchondral Cystic Lesions in the Distal Extremities in Thoroughbred Prospect Racehorses(Animals, 2023) Pérez-Nogués, Marcos; López San Román, Francisco Javier; Spirito, Michael; Manso Díaz, GabrielSubchondral cystic lesions (SCLs) in equines and their treatments have been mainly studied in the medial femoral condyle of the femur. SCLs in the distal extremities affecting the fetlock or interphalangeal joints are frequent, but treatment or prognosis studies in horses are currently sparse. Our objective was to compare four treatments for SCLs in the distal extremities (intralesional injection of corticosteroids, transcortical drilling, cortical screw placement, and absorbable hydroxyapatite implant placement) and report the racing prognoses for affected thoroughbred yearlings. Data from 113 thoroughbred yearlings treated for SCLs in the distal extremities were collected from 2014 to 2020. Age at surgery, sex, bone affected, radiographic SCL measurements, SCL shape, and type of treatment were recorded. Sale data and racing performance were collected for the operated horses and for 109 maternal siblings that were free of SCLs. An analysis was conducted to assess if SCL size affected racing prognosis and to detect differences in sale value and selected racing parameters between the cases and controls. The outcomes for the different treatments, the different bones affected, and the SCL shape type were also analyzed. There was no difference in the ability to start in a race between the cases and controls (60.2% vs. 69.7%, respectively). The auction value of the treated horses was significantly lower than that of their siblings. The bone affected did not impact any of the racing variables studied, whereas the height of the SCLs negatively affected the number of wins and placed races. The type of treatment for the horses affected by SCLs did not have an impact on sale prices, ability to start a race, race starts, wins, and places, or age at the time of the first start. In conclusion, yearlings diagnosed with an SCL in the distal extremities had lower auction prices and decreased racing performances, with lower numbers of wins correlated with larger SCL heights compared to the siblings. Similar racing performance was found regardless of the treatment received.