Person:
Garzón Jiménez, Nuria

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First Name
Nuria
Last Name
Garzón Jiménez
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Óptica y Optometría
Department
Optometría y Visión
Area
Optica
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UCM identifierORCIDScopus Author IDWeb of Science ResearcherIDDialnet IDGoogle Scholar ID

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Now showing 1 - 10 of 18
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    Revisiting Javal’s rule: a fresh and improved power vector approach according to age
    (Graefe's Archive for Clinical and Experimental Ophthalmology, 2023) Salvador Roger, Raquel; Albarran Diego, César; Garzón Jiménez, Nuria; García Montero, María; Muñoz, Gonzalo; Micó, Vicente; Estebe Taboada, José J.
    Purpose: The scientific community has established Javal’s rule as a model linking refractive (RA) and keratometric (KA) astigmatism since its appearance more than 100 years ago. The aim was to improve the accuracy of this relationship according to subject’s age by applying the power vector analysis. Posterior corneal curvature has also been studied. Methods: The IOLMaster 700 optical biometer was used to measure the corneal thickness and the radius of curvature of the anterior and posterior corneal surfaces. Refractive error was determined by a non-cycloplegic subjective refraction process with trial lenses. Linear regression analyses were applied using J0 and J45 power vector components. An evaluation was carried out according to the subject’s age resulting into eight regression relationships for each astigmatic vector component for each relationship. Results: A total of 2254 right eyes from 2254 healthy subjects were evaluated. A trend towards against-the-rule astigmatism (ATR) was found with aging, both for refractive astigmatism (RA) and keratometric astigmatism (KA), with 95.2% of subjects under 20 years old having with-the-rule (WTR) KA, and only 22.8% above 79 years old. The following regression equations were found between RA and KA: JRA0 = 0.73 × JKA0 − 0.18 (R = 0.78) and JRA45 = 0.70 × JKA45 + 0.04 (R = 0.69) and between RA and total corneal astigmatism (TCA): JRA0 = 0.73 × JTCA0 + 0.13 (R=0.78) and JRA45 = 0.70 × JTCA45 − 0.06 (R = 0.68) for the whole sample, but with sensible differences among age groups, both in the slope and in the intercept. Conclusion: Ignoring the age of the subject when using Javal’s rule could lead to an error in the final cylinder calculation that would increase in high astigmatisms. Applying this new power vector approach based on subject’s age could improve the accuracy of the astigmatism prediction.
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    Influence of angle kappa on visual and refractive outcomes after implantation of a diffractive trifocal intraocular lens
    (Journal of cataract and refractive surgery, 2020) Garzón Jiménez, Nuria; García Montero, María; López Artero, Esther; Albarrán Diego, Cesar Antonio; Pérez Cambrodí, Rafael José; Illarramendi Mendicute, Igor; Poyales Galán, Francisco
    Purpose: To evaluate changes in angle kappa following the implantation of a trifocal intraocular lens (IOL), and to assess the postoperative outcomes of patients with different angle kappa values. Setting: IOA Madrid Innova Ocular, Madrid, Spain Design: Prospective trial Methods: Sixty-three patients due to have bilateral implantation of the diffractive trifocal IOL (POD F, PhysIOL, Belgium) were included. Pupil offset was used as the best estimate of angle kappa and was measured using Pentacam (Oculus, Wetzlar, Germany) preoperatively and at 3-months after surgery. Postoperative refractive outcomes (sphere, cylinder, and MRSE) and visual outcomes at far, intermediate and near distance were assessed and compared between eyes with small pupil offset and eyes with large pupil offset. Quality of vision was assessed using a subjective questionnaire. Results: There was significant decrease in pupil offset post-operatively (mean: 0.197 ± 0.12 mm) compared to preoperatively (mean: 0.239 ± 0.12 mm), with a mean decrease of -0.042 mm (P = 0.0002). The same significant decrease was found for both the right eyes and left eyes, when analysed separately. No statistically significant difference was found in any of the refractive and visual acuity outcomes between eyes with small pupil offset and eyes with large pupil offset. The majority of patients (14 out of 16) complaining of significant halos had eyes with small pupil offset. Conclusion: Large pupil offset did not negatively affect visual and refractive outcomes. The tolerance to larger pupil offset might be due to the IOL optical design, with the first diffractive ring being larger than other commonly used multifocal IOLs. More studies comparing various diffractive IOL models will be useful to confirm such hypothesis.
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    Optical Behavior of an Enhanced Monofocal Intraocular Lens Compared with a Standard One
    (Applied Sciences, 2023) Albarrán Diego, César; García Montero, María; Garzón Jiménez, Nuria; González Fernández, Verónica; Gómez Pedrero, José Antonio
    The aim of this work was to compare an enhanced monofocal (RayOne EMV RAO200E, Rayner) and standard monofocal (RayOne RAO600C Aspheric, Rayner) intraocular lenses (IOLs) for three nominal powers (+10.00 D, +20.00 D and +30.00 D) as a function of the optical aperture diameter (pupil diameter) using a commercial Schlieren phase-shifting deflectometer NIMO TR1504 (Lambda-X, Belgium). From the wavefront maps measured by this instrument, the radial power profiles, the spherical aberration coefficients of the Zernike polynomial expansion (as a function of the optical aperture radius), and the root-mean-square (RMS) of the high-order aberrations (HOAs) were obtained and analyzed by comparing the two models. The results showed that the effective added power that could be obtained with the enhanced model depended directly on the pupil size and the power of the IOL implanted. The higher additions were achieved with the higher nominal IOL powers. The relationship between the pupil diameter, the corneal aberration of the patients and the power profile of these IOLs could have a crucial implication on the far distance and the final effective addition. However, it is important to note that these findings should be clinically validated through the implantation of these models in patients’ lenses.
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    Changes in Accommodative and Binocular Function following Phakic Intraocular Lens for High and Low-to-Moderate Myopia
    (International Journal of Environmental Research and Public Health, 2022) López Artero, Esther; Poyales Galán, Francisco; Garzón Jiménez, Nuria; Matamoros Hondarza, Alicia; Sáenz, Alba; Zhou, Ying; García Montero, María
    settingsOrder Article Reprints Open AccessArticle Changes in Accommodative and Binocular Function following Phakic Intraocular Lens for High and Low-to-Moderate Myopia by Esther López-Artero 1ORCID,Francisco Poyales 1,Nuria Garzón 1,2ORCID,Alicia Matamoros 1,Alba Sáez 1,Ying Zhou 3ORCID andMaría García-Montero 1,2,* 1 Miranza Group, C/Galileo 104, 28003 Madrid, Spain 2 Optometry and Vision Department, Faculty of Optics and Optometry, Complutense University of Madrid, 28037 Madrid, Spain 3 OCULUS Iberia, S.L., Tres Cantos, 28760 Madrid, Spain * Author to whom correspondence should be addressed. Int. J. Environ. Res. Public Health 2022, 19(11), 6716; https://doi.org/10.3390/ijerph19116716 Received: 27 April 2022 / Revised: 27 May 2022 / Accepted: 28 May 2022 / Published: 31 May 2022 Download Versions Notes Abstract The aim was to evaluate accommodative and binocular function of phakic intraocular lens implantable collamer lens (ICL) in high and low-to-moderate myopia. Prospective comparative cohort study with 38 myopic patients who underwent ICL implantation were divided into two groups of 19 patients, each one based on the spherical equivalent (SE): high-power (SE ≤ −6 D) and low-to-moderate (SE > −6 D). The push-up amplitude of accommodation (AA), monocular accommodative facility (MAF), distance and near ocular deviation, near convergence amplitude, near point convergence (NPC), stereopsis, and accommodative convergence/accommodation (AC/A) ratio were assessed before surgery and 1 week and 1 month postoperatively. The mean residual refractive error at 1 month after surgery improved in both groups, 0.18 ± 0.34 D and 0.09 ± 0.26 D, respectively (p < 0.001). There was a significant decrease in AA in both groups between preoperatively and at 1-week (p = 0.001; p = 0.008, respectively) and 1-month follow-up (p = 0.001; p = 0.008). For the rest of the binocular measurements, no statistically significant postoperative changes were found in any group. This finding suggests follow-up studies on amplitude of accommodation in phakic intraocular lens ICL implantation.
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    Feasibility of optical quality analysis system for the objetctive assessment of accommodation insufficiency: a phase 1 study
    (Journal of Optometry, 2020) López Artero, Esther; Garzón Jiménez, Nuria; Rodríguez Vallejo, Manuel; García Montero, María
    Purpose: To assess differences in a new objective metric obtained with a double-pass technique between a group with accommodation insufficiency (AI) and a control group and to explore the diagnostic capabilities of this new tool in comparison to conventional procedures. Methods: Retrospective cross-sectional case-control phase 1 study. Two groups age ranging from 8 to 18 years were recruitment: AI and control group. The diagnostic criterion of AI was based on monocular accommodative amplitude (AA) 2 D below Hofstetter’s calculation for minimum AA and monocular accommodative facility (MAF) failing with minus lens and cut-off at ≤ 6 cycles per minute. Accommodative response with a double pass device (HD Analyzer, Visiometrics) was measured, performing an evaluation from +1.00 D to −3.50D (−0.5D steps), offering the width of the profile at 50% (WP) in minutes of arc. Results: Differences were found between groups for the AA, MAF and MEM retinoscopy (p < 0.0001, p < 0.001, p = 0.037). The discriminative capacity of MEM retinoscopy for AI diagnosis was significant and the cut-off that maximized the sensitivity and specificity was > 0.5 D. Considering WP 50% in different points, the discriminative AI diagnosis capacities for the points of 2.0 D and 2.50 D were significant (ROC-AUC 0.78; p = 0.03 and p = 0.02). Conclusions: Double-pass system metric differed between patients with AI and control group, therefore the aim of a Phase I study was achieved. Further steps with higher sample sizes are required to evidence if the system really provides any advantage versus conventional methods in the diagnosis of AI.
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    Intraocular lens power calculation in eyes with keratoconus
    (Journal of Cataract & Refractive Surgery, 2020) Garzón Jiménez, Nuria; Arriola Villalobos, Pedro; Felipe Márquez, Gema; Poyales Galán, Francisco; García Montero, María
    The purpose was to review and document the methods used to calculate the power of the intraocular lens (IOL) to be implanted in cataract surgery in the specific scenario of eyes with keratoconus (KC). This review was conducted of all scientific articles published in English that focused on the parameters and formulas used to calculate the power of the IOL to be implanted in eyes with KC undergoing cataract surgery. There are few publications that show in detail how IOL power is calculated in those particular cases. If the keratometric value is used based on the standard refractive index (1.3375), this results in a postoperative refractive error with a tendency to hyperopia. The SRK/T formula is the formula yielding the best outcomes. The greater the severity of KC, the greater the deviation of the postoperative refractive status deviation from the target outcome.
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    Influence of trifocal intraocular lenses on standard automated refraction and aberrometer-based automated refraction
    (Journal of Cataract & Refractive Surgery, 2019) Garzón Jiménez, Nuria; García Montero, María; López Artero, Esther; Poyales Galán, Francisco; Albarrán Diego, Cesar Antonio
    Purpose: To study the agreement between manifest refraction (Rx) and objective refraction (ObjRx) measured with two autorefractor models and an aberrometer, in eyes implanted with a trifocal diffractive intraocular lens. Setting: IOA Madrid Innova Ocular, Madrid, Spain. Design: Prospective comparative cohort study. Methods: A Topcon KR8800 autorefractor, based on a Scheiner double-pinhole, and a NIDEK OPD-SCAN III aberrometer, based on the scanning-slit retinoscopy principle, were used to obtain objective refraction (ObjRx) readings. In addition, lower-order Zernike coefficients (Z) were used to calculate ObjRx. A set of 7 different results in power vector notation [M(spherical equivalent), J0 and J45] for 7 different methods was obtained: Rx, AR (automated refraction obtained with the KR8800), WF-P (Z-based ObjRx for the photopic pupil), WF-M (Z-based ObjRx for the mesopic pupil), WF-4 (Z-based ObjRx for a 4 mm pupil), OPD-C (automated refraction measured with the OPD under photopic conditions), and OPD-M (automated refraction measured with the OPD under mesopic conditions). Results: The study comprised 102 eyes from 51 cataract patients who underwent binocular implantation of the POD F IOL. All 6 objective methods yielded more negative M values than manifest refraction (Rx) (p < 0.001). As for the astigmatism components (J0 and J45), only AR (p = 0.003) and OPD-M (p < 0.001) differed significantly from Rx. The best and worst correlation for the M component were ICC=0.70 (for WF-M) and ICC=0.48 (WF-4). Conclusions: Objective methods tend to yield more negative sphere values than manifest refraction.
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    Visual and optical quality of enhanced intermediate monofocal versus standard monofocal intraocular lens
    (Graefe's Archive for Clinical and Experimental Ophthalmology, 2022) Albarrán Diego, Cesar Antonio; Garzón Jiménez, Nuria; Poyales Galán, Francisco; Rico del Viejo, Laura; Pérez Sanz, Lidia María; García Montero, María
    Purpose: Intraocular lens designs are constantly evolving, trying to obtain more spectacle independence after cataract surgery. This advantage can be linked to some disadvantages, such as optical quality decrease. For that reason, it is important to assess, not only the amount of vision provided but also the quality of vision once they are implanted. The purpose of the present work was to compare the visual performance between two monofocal intraocular models: a standard model and a monofocal with enhanced intermediate vision lens. Methods: Prospective, randomized, comparative study. Sixty adult subjects scheduled to undergo bilateral cataract surgery and IOL implantation were randomized to receive one of the two IOLs in both eyes at Miranza IOA, Madrid, Spain (group A: monofocal with enhanced intermediate vision lens and group B: standard monofocal lens). Monocular outcomes (right eyes) determined 1 and 3 months postoperatively were photopic corrected distance visual acuity (CDVA), uncorrected distance visual acuity (UDVA), perceived halo, corrected intermediate-distance contrast sensitivity, and higher-order aberrations. The impact of the new IOL in the postoperative management with autorefraction devices was also evaluated. Results: No differences were found in CDVA between the two groups. Significant differences were detected between the two lenses evaluated in both total HOA (p = 0.028) and internal HOA (p = 0.037). Contrast sensitivity and halometry results obtained at 1 month were similar across the two IOL groups. Conclusion: In patients undergoing cataract surgery, monofocal with enhanced intermediate vision IOL offered similar distance performance and contrast sensitivity along with perceived HOA and halos compared with the standard monofocal IOLs tested.
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    Forward-scattered and backward-scattered light in moderate keratoconus
    (Ophthalmic and Physiological Optics, 2023) Villanueva Gómez-Chacón, Celia; Viviano, Francesco; García Montero, María; Lorente Velázquez, Amalia; Martínez Alberquilla, Irene; Garzón Jiménez, Nuria
    Introduction: To evaluate the backscattered light, objective scatter index (OSI) and retinal straylight in patients with moderate keratoconus and healthy control subjects. Methods: A prospective observational study was developed with 33 patients in the moderate-keratoconus group (KC) and 34 in the non-keratoconus group (NKC). Corneal densitometry was obtained using Scheimpflug corneal tomography and measurements were expressed in grayscale units (GSU) over four zones within a 12.00 mm diameter around the corneal apex. A straylight meter was used to determine the amount of intraocular straylight under scotopic conditions, and the straylight parameter (LOG(s)) and test duration were recorded. The Optical Quality Analysis System based on the double-pass technique determined the OSI value. Results: Significant differences were observed between the KC and NKC groups for corneal densitometry (except in the 6–10 mm zone), OSI and retinal straylight. A moderate and significant correlation was found between OSI and retinal straylight LOG(s) (r = 0.52, p = 0.002). Weaker and non-significant correlations were found between corneal densitometry and the other parameters analysed (i.e., OSI, retinal straylight LOG(s) and retinal straylight times). Conclusions: Backscattered light, retinal straylight and the OSI show clear differences between healthy eyes and those with moderate KC. The changes present in the stages of KC evaluated in the current study (stages II and III according to the Amsler–Krumeich classification) might alter the scattering of the light entering the eye.
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    Design of an optical bench for polychromatic characterisation of advanced intraocular lens designs with spatial light modulator
    (2023) González Fernández, Verónica; Garzón Jiménez, Nuria; García Montero, María; Gómez Pedrero, José Antonio; Fernandez Nuñez, Sara; Albarrán Diego, César
    In recent years, the design of intraocular lenses (IOLs) has experienced a great deal of development and there is now a wide variety of designs. At the moment, some of the most interesting designs that allow for the greatest degree of innovation and customisation are lenses that combine a refractive part with a diffractive part