Person: Cortés Gardyn, Óscar
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First Name
Óscar
Last Name
Cortés Gardyn
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Veterinaria
Department
Producción Animal
Area
Producción Animal
Identifiers
5 results
Search Results
Now showing 1 - 5 of 5
Item The genetic ancestry of American Creole cattle inferred from uniparental and autosomal genetic markers(Scientific Reports, 2019) Ginja, Catarina; Gama, Luis Telo; Cortés Gardyn, Óscar; Martin Burriel, Inmaculada; Vega-Pla, Jose Luis; Penedo, Cecilia; Sponenberg, Phil; Cañón Ferreras, Francisco Javier; Sanz, Arianne; do Egito, Andrea Alves; Alvarez, Luz Angela; Giovambattista, Guillermo; Agha, Saif; Rogberg-Muñoz, Andrés; Cassiano Lara, Maria Aparecida; Afonso, Sónia; Aguirre, Lenin; Armstrong, Eileen; Camacho Vallejo, Maria Esperanza; Canales, Amado; Cassamá, Bernardo; Contreras, Gloria; Cordeiro, J. M. Moras; Elbeltagy, Ahmed; Fioravanti, Maria Clorinda Soares; Gómez Carpio, Mayra; Gómez, Mariano; Hernández, Antonio; Hernandez, Darwin; Juliano, Raquel Soares; Landi, Vincenzo; Marques, Ribamar; Martínez, Rubén D.; Martínez, O. Roberto; Melucci, Lilia; Molina Flores, Baldomero; Mújica, Fernando; Parés i Casanova, Pere-Miquel; Quiroz,Jorge; Rodellar, Clementina; Tjon, Gerald; Adebambo, Tumininu; Uffo, Odalys; Vargas, Julio César; Villalobos, Axel; Zaragoza, Pilar; Dunner Boxberger, Helene Susana; Delgado, Juan Vicente; Martinez, AmparoCattle imported from the Iberian Peninsula spread throughout America in the early years of discovery and colonization to originate Creole breeds, which adapted to a wide diversity of environments and later received influences from other origins, including zebu cattle in more recent years. We analyzed uniparental genetic markers and autosomal microsatellites in DNA samples from 114 cattle breeds distributed worldwide, including 40 Creole breeds representing the whole American continent, and samples from the Iberian Peninsula, British islands, Continental Europe, Africa and American zebu. We show that Creole breeds differ considerably from each other, and most have their own identity or group with others from neighboring regions. Results with mtDNA indicate that T1c-lineages are rare in Iberia but common in Africa and are well represented in Creoles from Brazil and Colombia, lending support to a direct African influence on Creoles. This is reinforced by the sharing of a unique Y-haplotype between cattle from Mozambique and Creoles from Argentina. Autosomal microsatellites indicate that Creoles occupy an intermediate position between African and European breeds, and some Creoles show a clear Iberian signature. Our results confirm the mixed ancestry of American Creole cattle and the role that African cattle have played in their development.Item Rationalizing ex situ collection of reproductive materials for endangered livestock breed conservation(Ecological and Economics, 2021) De Oliveira Silva, Rafael ; Cortés Gardyn, Óscar; Hiemstra, Sipke-Joost; Oliveira Marques, Joao ; Tixier-Boichard, Michele; Moran, DominicImprovements in ex situ storage of genetic and reproductive materials offer an alternative for endangered livestock breed conservation, but collections should be optimized cost-effectively to avoid duplication, and with reference to the sustainability of in situ breeds. We developed a multi-period chance-constrained optimization model to rationalize collections of endangered livestock breeds at risk of in situ extinction in Spain. The model configures collections by determining the least-cost optimal collection locations, timing and material quantities (semen doses). A decision variable defining an “acceptable level of risk” allows decision makers to specify tolerable levels of in situ breed endangerment when taking ex situ collection and storage decisions. Using data from 18 gene banks we demonstrate how collections can be rationalized, and derive cost curves relating marginal ex situ collection cost and accepted probability of in situ extinction covering the period 2018 to 2060. The modelling framework can be replicated in countries seeking to rationalize ex situ collections under limited conservation budgets and uncertain in situ extinction risks.Item Genomic Characterization of a Set of Iberian Peninsula Bovine Local Breeds at Risk of Extinction: Morenas Gallegas(Animals, 2020) García-Atance, María Asunción; Carleos, Carlos; Dunner Boxberger, Helene Susana; Eusebi, Paulina G.; Rivero, Castor José; Justo, José Ramón; Fernández, Miguel; Cañón Ferreras, Francisco Javier; Cortés Gardyn, ÓscarA set of five local bovine breeds in danger of extinction named Cachena, Caldelá, Limiá, Frieiresa, and Vianesa and included in the group of Morenas Gallegas are located in the Autonomous Community of Galicia at the Northwest of Spain. Local authorities launched a conservation plan at the end of the 21th century in order to preserve this important genetic reservoir. However, Morenas Gallegas bovine breeds never have been analyzed with genomic tools and this information may be crucial to develop conservation plans. The aim of the study was to analyze their genetic diversity and genetic relationships with a set of local and cosmopolitan European bovine breeds using single nucleotide polymorphisms. Our results show own genetic signatures for the Morenas Gallegas breeds which form a separate cluster when compared to the Spanish breeds analyzed, with the exception of the Cachena breed. The genetic diversity levels of the Morenas Gallegas were intermediate or high, and low inbreeding coefficients can be found except for the Frieiresa breed (11%). Vianesa breed evidenced two lineages depending on the Frieiresa component influence. The Morenas Gallegas bovine breeds group represent an important Spanish bovine genetic reservoir and despite their classification within a single generic group, the five breeds show their own genetic uniqueness.Item Detection of selection signatures for agonistic behaviour in cattle(Journal of Animal Breeding and Genetics, 2018) Eusebi, Paulina; Cortés Gardyn, Óscar; Carleos, Carlos; Dunner Boxberger, Helene Susana; Cañón Ferreras, Francisco JavierThe identification of genomic regions including signatures of selection produced by domestication and its subsequent artificial selection processes allows the understanding of the evolution of bovine breeds. Although several studies describe the genomic variability among meat or milk production cattle breeds, there are limited studies orientated towards bovine behavioural features. This study is focused on mapping genomic signatures of selection which may provide insights of differentiation between neutral and selected polymorphisms. Their effects are studied in the Lidia cattle traditionally selected for agonistic behaviour compared with Spanish breeds showing tamed behaviour. Two different approaches, BayeScan and SelEstim, were applied using genotypic 50K SNP BeadChip data. Both procedures detected two genomic regions bearing genes previously related to behavioural traits. The frequencies of the selected allele in these two regions in Lidia breed were opposite to those found in the tamed breeds. In these genomic regions, several putative genes associated with enriched metabolic pathways related to the behavioural development were identified, as neurochondrin gene (NCDN) or glutamate ionotropic receptor kainate type subunit 3 (GRIK3) both located at BTA3 or leucine-rich repeat and Ig domain containing 2 (LINGO2) and phospholipase A2-activating protein (PLAA) at BTA8.Item Comparison of diversity parameters from SNP, microsatellites and pedigree records in the Lidia cattle breed(Livestock Sicence, 2019) Eusebi, Paulina; Cañón Ferreras, Francisco Javier; Dunner Boxberger, Helene Susana; Cortés Gardyn, Óscar; Sevane Fernández, NataliaGenetic drift, loss of heterozygosity and decrease in genetic variability are consequences of high rates of inbreeding over generations. High density single nucleotide polymorphisms arrays offered new possibilities to estimate inbreeding coefficients more accurately than those from pedigree records or microsatellites genotypes. In the present study different inbreeding coefficients were estimated and compared from SNP data: (1) runs of homozygosity of different length (>1Mb, > 4Mb, > 8Mb and > 16Mb), (2) inbreeding coefficients based on the observed vs. expected number of homozygous genotypes and (3) standardized observed homozygosity, from pedigree records and from three microsatellite derived diverse metrics. SNP inbreeding coefficients ranging from 0.14 to 0.26 and shown correlations ≥ 0.84 among them. The correlation among SNP and pedigree inbreeding coefficients was moderate ranged from 0.37 to 0.5 and low than the expected correlation. The limited pedigree depth of the Lidia cattle breed as revealed the average number of equivalent complete generations (5.5) probably explain that the higher correlation coefficient with pedigree records was with the runs of homozygosity of high length (>16Mb). Also, the absence of identity disequilibrium on our molecular data could explain the moderate correlation values (0.43–0.54 in absolute values) among microsatellite derived metrics and SNP inbreeding coefficients.