Person:
Martínez De Merlo, Elena

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First Name
Elena
Last Name
Martínez De Merlo
URI
https://hdl.handle.net/20.500.14352/80431
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Veterinaria
Department
Medicina y Cirugía Animal
Area
Medicina y Cirugía Animal
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    Pancreatic adenocarcinoma treated with surgical resection, toceranib phosphate and firocoxib in a dog: a case report
    (Veterinary Research Communications, 2024) Fuertes Recuero, Manuel; Martínez De Merlo, Elena; Lizasoain Sanz, Guillermo; Arroba Alonso, Amanda; Sánchez López, Alejandro; Suárez Redondo, María; Ortiz Díez, Gustavo; Vázquez Fernández, Esther
    Exocrine pancreatic carcinomas are rarely reported in dogs. A ductal pancreatic adenocarcinoma in a 10-year-old intact beagle is described in this report. The diagnosis was made based on clinical signs, imaging (abdominal ultrasound and CT scan) and histopathology. Treatment consisted of partial right lobe pancreatectomy followed by adjuvant therapy with toceranib phosphate (Palladia®) and firocoxib (Previcox®) for six months. The treatment was well tolerated, and the survival time was 445 days. To our knowledge, this is the longest survival reported in the literature for a dog diagnosed with exocrine pancreatic adenocarcinoma. The results described here may contribute to provide a better understanding about this neoplasia and potential treatment options.
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    Synovial myxosarcoma in the scapulohumeral joint of a dog: a case report
    (Veterinary Research Communications, 2024) Mínguez Pereira, Elena; Martín Carrasco, Laura; García Fernández, Rosa Ana; Fraile Fernández, Andrés; Ortiz Díez, Gustavo; Martínez De Merlo, Elena; García Real, María Isabel
    A 12-year-old, 3 kg spayed female mixed-breed dog was evaluated to assess a 1-year history of intermittent right forelimb lameness that did not have adequate response to nonsteroidal anti-inflammatory drugs. The radiographic study performed under sedation showed multifocal radiolucent areas affecting both the right humerus and scapula with focal soft tissue swelling; a CT scan confirmed the existence of an aggressive and invasive soft tissue mass affecting the scapulohumeral joint. Fine needle aspiration results suggested a low-grade synovial sarcoma and therefore a scapulectomy was performed. The biopsy showed spindle to stellated cells immersed in a basophilic and mucinous (myxoid) matrix with mild to moderate anisocytosis, moderate anisokaryosis, some binucleated cells and sporadic multinucleated cells. These findings are consistent with low-grade synovial myxosarcoma, a not well described synovial neoplasm that can mimic other commonly seen joint tumors or even septic arthritis on radiographs. The purpose of this case report is to describe the first reported synovial myxosarcoma affecting the scapulohumeral joint of a small dog.