Person:
González Alonso-Alegre, Elisa-Margarita

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First Name
Elisa-Margarita
Last Name
González Alonso-Alegre
URI
https://hdl.handle.net/20.500.14352/80512
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Veterinaria
Department
Medicina y Cirugía Animal
Area
Medicina y Cirugía Animal
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2015 - 20192
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Author: Rodríguez Álvaro, Alfonso × Subject: 636.09:617.7 ×

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    Atypical chorioretinal coloboma in a Golden Retriever: a retinographic, fluorographic, and optical coherence tomography study
    (Veterinary Ophthalmology, 2015) González Alonso-Alegre, Elisa-Margarita; Rodríguez Álvaro, Alfonso; Esteban Martin, Javier
    Purpose: To report a case of canine atypical chorioretinal coloboma where ophthalmoscopic, fluoroangiographic and optical coherence tomography characteristics are described. Animal Studied: A 2-year-old Golden Retriever dog in which routine ophthalmoscopic examination allowed diagnosis of a posterior coloboma on the left eye. Procedures: Retinography, fluorescein angiography, and optical coherence tomography were performed to characterize the lesion of the left fundus. Results: Ophthalmoscopy revealed a pigmented circumscribed lesion dorsal to the optic nerve of the left fundus, surrounded by small areas of hyper-reflectivity and retinal vessels with an abnormal pattern. Fluoroangiography revealed a constant hypofluorescence of the defect and a complete altered vascular pattern associated with the coloboma. Optical coherence study demonstrated an important craterlike depression showing an atrophic neurosensory retina, and a lack of retinal pigment epithelium and choroidal tissue. Conclusions: Fluoroangiographic and optical coherence tomographic studies of an atypical chorioretinal coloboma in a dog are reported for the first time. Both imaging techniques are of great importance to characterize this type of congenital defects.
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    Characterization of corneal impression cyotology in dogs and its application in the diagnosis of keratoconjunctivitis sicca
    (The Veterinary Record, 2019) Lejarza Illaro, Mikel; Rodríguez Álvaro, Alfonso; Sánchez Maldonado, María Belén; González Alonso-Alegre, Elisa-Margarita
    Objective: Determine morphological and morphometric parameters of corneal epithelium in dogs, and determine the cellular alterations that occur in canine keratoconjunctivitis sicca (KCS) using impression cytology. Study animals: 60 dogs divided into 2 groups: dogs with Schirmer tear test (STT) ≥ 15 mm/min and absence of ocular disease, and dogs with STT < 15 mm/min and clinical signs of KCS. Procedures: Impression cytology was used to collect corneal samples. The percentage of eyes with cell changes, the number of such cells and the percentage of cells with structural alterations in each group were determined. The possible correlation between corneal epithelium alterations and decreased tear production was evaluated. Results: A significant positive correlation existed between STT and the area of the cytoplasm and nucleus of corneal cells. A significant negative correlation was found between STT and the nucleus/cytoplasm (N:C) ratio, and the presence of cellular changes. Significant difference existed between the number of pyknotic nuclei, being higher among animals with all stages of KCS. Conclusion: Corneal impression cytology can be used to assess the corneal epithelium in healthy eyes and eyes with KCS, demonstrating its usefulness as a diagnostic tool especially in mild and early cases.