Person:
Santurde Sánchez, Gloria

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First Name
Gloria
Last Name
Santurde Sánchez
URI
https://hdl.handle.net/20.500.14352/80656
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Veterinaria
Department
Sanidad Animal
Area
Sanidad Animal
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    Klebsiella pneumoniae sequence type 11 from companion animals bearing ArmA methyltransferase, DHA-1 β-lactamase, and QnrB4
    (Antimicrobial agents and chemotherapy, 2013) Hidalgo, Laura; Gutiérrez, Belén; Martínez Ovejero, Cristina; Carrilero Aguado, Laura; Matrat, Stephanie; Saba, Courage K S; Santos López, Alfonso; Thomas López, Daniel; Hoefer, Andreas; Suárez Rodríguez, Mónica; Santurde Sánchez, Gloria; Martín Espada, María Del Carmen; González Zorn, Bruno
    Seven Klebsiella pneumoniae isolates from dogs and cats in Spain were found to be highly resistant to aminoglycosides, and ArmA methyltransferase was responsible for this phenotype. All isolates were typed by multilocus sequence typing (MLST) as ST11, a human epidemic clone reported worldwide and associated with, among others, OXA-48 and NDM carbapenemases. In the seven strains, armA was borne by an IncR plasmid, pB1025, of 50 kb. The isolates were found to coproduce DHA-1 and SHV-11 β-lactamases, as well as the QnrB4 resistance determinant. This first report of the ArmA methyltransferase in pets illustrates their importance as a reservoir for human multidrug-resistant K. pneumoniae.