Person:
Andrés Gamazo, Paloma Jimena De

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First Name
Paloma Jimena De
Last Name
Andrés Gamazo
URI
https://hdl.handle.net/20.500.14352/80475
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Veterinaria
Department
Medicina y Cirugía Animal
Area
Medicina y Cirugía Animal
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2007 - 20092
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End date: 2009 × Start date: 2007 ×

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Now showing 1 - 2 of 2
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    Comparison of non-selective adrenocorticolysis with mitotane or trilostane for the treatment of dogs with pituitary-dependent hyperadrenocorticism
    (Veterinary Record, 2007) Clemente, Mónica; Andrés Gamazo, Paloma Jimena De; Arenas, Carolina; Melián, Carlos; Morales, Manuel; Pérez Alenza, María De Los Dolores
    Forty-six dogs with pituitary-dependent hyperadrenocorticism were treated with mitotane by the non-selective adrenocorticolysis protocol and 40 were treated twice a day with trilostane. The treatment groups were compared by chi-squared tests, and survival data were analysed using Kaplan-Meier survival plots and a Cox proportional hazard method. The non-selective adrenocorticolysis protocol was very effective (89 per cent), its toxicity was moderate (24 per cent) and there were fewer recurrences (29 per cent) than reported with the classical selective adrenocorticolysis protocol (58 per cent). In a multivariate model, age and bodyweight at diagnosis were significantly negatively correlated with survival time. The median survival time of the dogs treated with trilostane twice a day (900 days) was longer (P=0·05) than that of the dogs treated with mitotane (720 days).
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    Survival time of dogs with inflammatory mammary cancer treated with palliative therapy alone or palliative therapy plus chemotherapy
    (Veterinary Record, 2009) Clemente, Mónica; Andrés Gamazo, Paloma Jimena De; Peña Fernández, Laura Luisa; Pérez Alenza, María De Los Dolores
    Seven of 30 female dogs diagnosed with inflammatory mammary cancer were given chemotherapy and palliative treatment, and the other 23 received only palliative treatment. The median survival time of the seven dogs given chemotherapy was 57 days, compared with 35 days for the 23 given only palliative treatment.