Person:
Iniesta Albentosa, Margarita Isabel

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First Name
Margarita Isabel
Last Name
Iniesta Albentosa
URI
https://hdl.handle.net/20.500.14352/79820
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Odontología
Department
Especialidades Clínicas Odontológicas
Area
Estomatología
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Author: Herrera González, David × Subject: 616.314-083 ×

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    Dental Biofilm Removal and Bacterial Contamination of a New Doubled-Side Thermoplastic Polyurethane-Based Toothbrush: A Crossover Study in Healthy Volunteers
    (Antibiotics, 2022) Zúñiga Uhalde, Ignacio; Iniesta Albentosa, Margarita Isabel; Virto Ruiz, Leire; Ribeiro Vida, Honorato José; Alonso Español, Andrea; Hernández Ruiz de Azcárate, Fernando; Cardona Álvarez, John Jairo; Maher Lavandero, Anushiravan; Alonso Álvarez, Bettina María; Sanz Alonso, Mariano; Herrera González, David
    Multiple toothbrush designs have been developed to enhance dental biofilm removal and decrease bacterial contamination and retention over time. Therefore, the aim of this clinical study was to compare the efficacy of a prototype of a new double-sided thermoplastic polyurethane-based toothbrush with that of a conventional nylon-bristle toothbrush. A crossover study was conducted in systemically healthy volunteers (n = 24) for two one-week periods plus one washout week. As outcome variables, plaque and gingival indices, total bacterial contamination of the toothbrushes by quantitative polymerase chain reaction (qPCR), and patient-reported outcomes were measured. Clinical and microbiological variables were analysed using a general linear model and Friedman and Wilcoxon signed-rank tests. No statistically significant differences between toothbrushes were detected neither for full-mouth PlI (p > 0.05) nor for GI (p > 0.05). Similarly, no statistically significant differences were detected for bacterial contamination after 40 seconds or 1 week of use, with results expressed either in CFU/mL or in CFU/mm2 (p > 0.05). In conclusion, the tested prototype toothbrush was as effective and safe as the control toothbrush, and the participating subjects did not experience any adverse effects from its use and rated its efficiency and effectiveness in cleaning their teeth as satisfactory.