Person:
Canfrán Arrabe, Susana

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First Name
Susana
Last Name
Canfrán Arrabe
URI
https://hdl.handle.net/20.500.14352/80354
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Veterinaria
Department
Medicina y Cirugía Animal
Area
Medicina y Cirugía Animal
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2018 - 201932020 - 20243
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Author: Bustamante Domínguez, Rocío × Item Type: Publication ×

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Now showing 1 - 6 of 6
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    Project number: 297
    Gamificación en anestesiología clínica veterinaria
    (2019) Canfrán Arrabe, Susana; Álvarez Gómez De Segura, Ignacio; Cediel Algovia, Rafael; Aguado Domínguez, Delia; Bustamante Domínguez, Rocío; García Sanz, Virginia; García Gómez, Andrea; Grijota Chousa, Óscar José; Morcuende Rodríguez, África
    En el presente proyecto se propuso el desarrollo de un juego de mesa que permitiese el aprendizaje de conceptos teóricos relacionados con la anestesia en un entorno de gamificación. La gamificación se define como el empleo de mecánicas de juego en entornos y aplicaciones no lúdicas con el fin de potenciar la motivación, la concentración y el esfuerzo. Con ello se pretendía complementar la docencia teórica de la asignatura de Cirugía General y Anestesia de cuarto curso de Grado en Veterinaria. Este recurso y la metodología planteada han pretendido facilitar y mejorar el aprendizaje de diversos conceptos de anestesiología clínica en el ámbito de la docencia del Grado en Veterinaria. Con ello, se pretendía mejorar la adquisición de una serie de competencias necesarias para los graduados en Veterinaria, de cara a poder desempeñar adecuadamente su actividad práctica clínica.
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    Intraoperative effect of low doses of ketamine or dexmedetomidine continuous rate infusions in healthy dogs receiving propofol total intravenous anaesthesia and epidural anaesthesia: A prospective, randomised clinical study
    (Research in Veterinary Science, 2022) Bustamante Domínguez, Rocío; Canfrán Arrabe, Susana; Álvarez Gómez De Segura, Ignacio; Aguado Domínguez, Delia
    The present study aimed to determine the effect of either ketamine or dexmedetomidine constant rate infusion (CRI) on intraoperative propofol anaesthetic requirements during total intravenous anaesthesia (TIVA) in healthy dogs undergoing hindlimbs orthopaedic procedures receiving epidural anaesthesia. In this randomised, blinded clinical study, thirty-nine healthy client-owned dogs were premedicated intramuscularly (dexmedetomidine 4 μg/kg and methadone 0.3 mg/kg). General anaesthesia was induced to effect with propofol administered as intravenous bolus, and maintained with propofol TIVA (18 mg/kg/h), adjusted to meet the suitable clinical anaesthetic depth (indicatively±20%) based on clinical judgement. Lumbosacral epidural anaesthesia was performed using bupivacaine (1 mg/kg) and morphine preservative free (0.1 mg/kg). Dogs randomly received either saline (SP; loading dose 1 mL/kg, CRI 1 mL/kg/h), or ketamine (KP; loading dose 1.5 mg/kg, CRI 1.5 mg/kg/h), or dexmedetomidine (DP; loading dose 1 μg/kg/, CRI 1 μg/kg/h). Physiological variables were recorded intraoperatively at 5-min intervals using standard-of-care monitoring. Recovery quality and duration were recorded. Treatment groups were compared with parametric and non-parametric tests as appropriate, p < 0.05. Propofol rates and recovery scores were similar between groups. Overall mean and diastolic blood pressures were higher in group DP compared to group KP (12–14 mmHg, p = 0.016 and p = 0.015, respectively). More dogs required mechanical ventilation in group KP (12 dogs) than in either group SP or DP (7 dogs per group, p = 0.037). Ketamine or dexmedetomidine CRIs, at the studied rates, did not reduce propofol TIVA requirements in dogs undergoing orthopaedic surgery with epidural anaesthesia.
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    Project number: 162
    Desarrollo de vídeos doodle como apoyo a la docencia en anestesiología veterinaria
    (2018) Aguado Domínguez, Delia; Álvarez Gómez De Segura, Ignacio; Cediel Algovia, Rafael; Canfrán Arrabe, Susana; Bustamante Domínguez, Rocío; García Sanz, Virginia; Romana Muñoz, Sara
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    Project number: 172
    Gamificación en Anestesiología Clínica Veterinaria: Ampliación
    (2020) Aguado Domínguez, Delia; Álvarez Gómez De Segura, Ignacio; Cediel Algovia, Rafael; Bustamante Domínguez, Rocío; Canfrán Arrabe, Susana; Arenillas Baquero, Mario; López Ramis, Víctor; García Sanz, Virginia; Grijota Chousa, Óscar José; Gámez Maidanskaia, Ekaterina; Romero Marco, Patricia; García Gómez, Andrea; González Lendínez, Andrea
    Desarrollo de un juego de mesa que permitan el aprendizaje de conceptos teóricos relacionados con la anestesia en un entorno de gamificación.
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    Clinical comparison of the effects of isoflurane or propofol anaesthesia on mean arterial blood pressure and ventilation in dogs undergoing orthopaedic surgery receiving epidural anaesthesia
    (Veterinary Journal, 2018) Canfrán Arrabe, Susana; Álvarez Gómez De Segura, Ignacio; Cediel Algovia, Rafael; Bustamante Domínguez, Rocío; Aguado Domínguez, Delia
    The aim of this study was to compare the effects on mean arterial pressure (MAP) and ventilation of propofol total IV anaesthesia (TIVA) and isoflurane as anaesthetic maintenance in healthy dogs undergoing orthopaedic surgery, with epidural anaesthesia. Dogs were premedicated IM with dexmedetomidine (4 μg/kg) and methadone (0.3 mg/kg), induced with IV propofol (0.65–5 mg/kg) and randomly assigned to be maintained with isoflurane (group I) or propofol (group P). Isoflurane end-tidal concentration (EtISO) and propofol infusion rate were adjusted during the surgery to maintain a suitable anaesthetic depth. All dogs received bupivacaine (1 mg/kg) and morphine (0.1 mg/kg) in the lumbosacral epidural space (total volume 0.2 mL/kg). MAP was recorded every 5 min during the procedure. Statistical analysis was performed using parametric (Student's t test) and nonparametric (Mann–Whitney U-test, chi-square) tests, as appropriate. Anaesthetic maintenance in groups I and P was accomplished by providing a mean EtISO of 1.12 ± 0.15% and a mean propofol infusion rate of 15.0 ± 4.7 mg/kg/h, respectively. MAP was significantly higher in group P than in group I (92 ± 17 mmHg versus 78 ± 10 mmHg; P = 0.021). Eleven dogs in group P and two dogs in group I reached an EtCO2 > 7.3 kPa, requiring mechanical ventilation (P = 0.001). In combination with epidural anaesthesia, propofol TIVA improved MAP and is a suitable alternative to isoflurane in orthopaedic surgery of the hind limb in healthy dogs. Nevertheless, since it was associated with increased respiratory depression, mechanical ventilation should be available.
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    Clinical evaluation of the sedative, antinociceptive and cardiorespiratory effects of intranasal dexmedetomidine combined with methadone in healthy dogs
    (The Veterinary Journal, 2024) Bustamante Domínguez, Rocío; Gómez de Segura IA; Canfrán Arrabe, Susana
    In this prospective, randomised, blinded clinical study, we compared the sedative, antinociceptive and cardiorespiratory effects of intranasal (IN) dexmedetomidine at 5 μg/kg (diluted with 0.03 mL/kg NaCl 0.9%, DEX) with or without methadone (0.3 mg/kg; DEXMET), through a mucosal atomization device to one nostril in twenty healthy client-owned dogs. At 5-min intervals over 45 min, sedation score, onset, cardiopulmonary variables, mechanical nociceptive thresholds (MNTs) were assessed, also ease of administration, adverse effects, and response to IV catheterization. Statistical analysis employed t-test, the Mann-Whitney U, repeated measures ANOVA and Chi-square tests as appropriate (P < 0.05). Higher sedation ocurred in DEXMET (7 [5–10]) compared to DEX (5 [2–7]) from 15 to 30 min (P < 0.01, median [interquartile range]). Heart rate was lower in DEXMET (P < 0.01; 65% reduction vs. 41% in DEX, P = 0.001). The MNTs were higher in DEXMET than DEX from 15 to 45 min (P < 0.01), peaking at T30 (17.1 ± 3.8, DEXMET and 8.5 ± 5.4 N, DEX). No differences were observed in mean arterial blood pressure and respiratory rate. Intranasal administration was considered easy for 8 dogs per group. Reverse sneezing (8 dogs; P < 0.001), sialorrhea and retching (4 and 2 dogs, respectively) occurred in DEXMET. Response to catheterisation was lower in DEXMET than DEX (P = 0.039; 2 and 7 dogs, respectively). In conclusion, intranasal methadone (0.3 mg/kg) increased the sedative and antinociceptive effects produced by dexmedetomidine (5 μg/kg) in healthy dogs and resulted in lower heart rate.