Person: Prados Frutos, Juan Carlos
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First Name
Juan Carlos
Last Name
Prados Frutos
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Medicina
Department
Area
Anatomía y Embriología Humana
Identifiers
6 results
Search Results
Now showing 1 - 6 of 6
Item Anatomic relationship of the proximal nail matrix to the extensor hallucis longus tendon insertion(European Academy of Dermatology and Venereology, 2015) Palomo López, P.; López López, D.; M.E. Losa Iglesias; Becerro De Bengoa Vallejo, Ricardo; Prados Frutos, Juan Carlos; Murillo González, Jorge AlfonsoBackground: The purpose of this study was to delineate the relationship of the terminal extensor hallucis longus tendon insertion to the proximal limit of the nail matrix of the great toe. Material and methods: Fifty fresh-frozen human cadaver great toes with no evidence of trauma (average age, 62.5 years; 29 males and 21 females) were used for this study. Under 25X magnification, the proximal limit of the nail matrix and the terminal bony insertion of the extensor hallucis longus tendons were identified. The distance from the terminal tendon insertion to the nail matrix was ascertained using precision calipers, an optical microscope, and autocad(®) software for windows. Twenty-five great toes were placed in a neutral formalin solution and further analysed by histological longitudinal-sections. The specimens were stained with haematoxylin and eosin and examined microscopically to determine the presence of the extensor hallucis longus tendon along the dorsal aspect of the distal phalanx of each great toe. Results: The main result we found in great toes was that the extensor tendon is between the matrix and the phalanx and extends dorsally to the distal aspect of the distal phalanx in all, 100%, specimens. The nail matrix of the great toe is not attached to the periosteum of the dorsal aspect of the base of the distal phalanx as is the case for fingers, because the extensor hallucis tendon is plantar or directly underneath the nail matrix and the tendon is dorsal to the bone. Conclusions: We have found that the extensor tendon is between the matrix and the phalanx and extends dorsally to the distal aspect of the distal phalanx. The nail matrix of the great toe is not attached to the periosteum of the dorsal aspect of the base of distal phalanx as is the case in fingers, because the extensor hallucis tendon is plantar or directly underneath the nail matrix and the tendon is dorsal to the bone. Our anatomic study demonstrates that the proximal limit of the matrix and nail bed of the human great toe are dorsal and overlapping the terminal extensor hallucis longus tendon until its distal bony insertion in all specimens.Item A new technique for feeding dogs with a congenital cleft palate for surgical research(Laboratory Animals, 2011) López-Gordillo, Yamila et al.; González-Meli, B; Martínez Sanz, Elena; Casado Gómez, Inmaculada; Martín Álvaro, María Concepción; González Aranda, Pablo; Paradas Lara, Irene; Maldonado Bautista, Estela; Maestro De Las Casas, María Del Carmen; Prados Frutos, Juan Carlos; Martínez Álvarez, María ConcepciónIn humans, cleft palate (CP) is one of the most common malformations. Although surgeons use palatoplasty to close CP defects in children, its consequences for subsequent facial growth have prompted investigations into other novel surgical alternatives. The animal models of CP used to evaluate new surgical treatments are frequently obtained by creating surgically induced clefts in adult dogs. This procedure has been ethically criticized due to its severity and questionable value as an animal model for human CP. Dogs born with a congenital CP would be much better for this purpose, provided they developed CP at a sufficient rate and could be fed. Up until now, feeding these pups carried the risk of aspiration pneumonia, while impeding normal suckling and chewing, and thus compromising orofacial growth. We developed a technique for feeding dog pups with CP from birth to the time of surgery using two old Spanish pointer dog pups bearing a complete CP. This dog strain develops CP in 15-20% of the offspring spontaneously. Custom-made feeding teats and palatal prostheses adapted to the pups' palates were made from thermoplastic plates. This feeding technique allowed lactation, eating and drinking in the pups with CP, with only sporadic rhinitis. To determine whether the use of this palatal prosthesis interferes with palatal growth, the palates of three littermate German shorthaired pointer pups without CP, either wearing or not wearing (controls) the prosthesis, were measured. The results showed that the permanent use of this prosthesis does not impede palatal growth in the pups.Item Three-dimensional descriptive study of the pterygomaxillary region related to pterygoid implants: A retrospective study(Scientific Reports, 2019) Salinas Goodier, Carmen; Rojo, Rosa; Murillo González, Jorge Alfonso; Prados Frutos, Juan CarlosThe objective of this study was to analyze three-dimensionally the morphological characteristics of the pterygomaxillary region related to pterygoid implants. Volume, height, width and bone density were studied in relation to age, sex and dental status. This retrospective observational study analyzed the CBCT of 52 hemi-maxillas three-dimensionally (females n = 28, males n = 24; dentate = 31, edentulous = 21). Patients were exposed between September 2009 and October 2014, and data collection was performed between November 2015 and May 2016. Bone density, volume, height and width were analyzed in various locations of the maxilla and pterygoid process, and the variables age, gender and dental status patients were compared. The results show that the mean width of the pterygomaxillary joint was 7.5 mm (SD 1.00 mm), mean height was 12.51 mm (SD 1,82 mm) and mean volume was 321.7 mm3 (SD 142.02 mm3). Statistically significant differences between dentate and edentulous patients were found, showing a higher osseous density in dentate patients in the pterygoid process (758.2, SD 106.8, 95% CI 729.2 to 787.3 GSD - Gray Scale Density - compared to 689.9, SD 107.3, 95% CI 660.8 to 719.1 GSD; P = 0.022). In the maxilla, density was statistically significant lower in female subjects (571.0, SD 74.1, 95% CI 594.9 to 645.4 GSD) than in male subjects (620.2, SD 93.8, 95% CI 594.4 to 645.4 GSD, P = 0.047). In conclusion, due to the significant variation in the morphological characteristics of the pterygomaxillary region among subjects, personalized pre-surgical radiologicalassessment should always be performed. Gender, age and dental status are critical factors as they significantly affect bone density in this region.- Project number: 166
Item Obtención de imágenes anatómicas de huesos y articulaciones correlacionadas con RX y RM para el aprendizaje auto-dirigido de la anatomía topográfica del miembro inferior.(2016) Murillo González, Jorge Alfonso; Barrio Asensio, María Del Carmen; Herrera Lara, Manuel Eugenio; Arráez Aybar, Luis Alfonso; Cabrera Parra, Walter; Becerro de Bengoa Vallejo, Ricardo; Prados Frutos, Juan Carlos; Gutierrez San José, María Begoña; Quirós Terrón, LuisDesarrollo de un sistema interactivo para mejorar el proceso de enseñanza-aprendizaje en la docencia de la osteología y artrología del miembro inferior, que pueda ser utilizado por los alumnos de Grado de Ciencias de la Salud a través del Campus. Item Long-term clinical behavior and complications of intentionally tilted dental implants compared with straight implants supporting fixed restorations: A systematic review and metaanalysis(Biology, 2021) Cortés Bretón Brinkmann, Jorge; García-Gil, Ignacio; Pedregal Patricia; Peláez Rico, Jesús; Prados Frutos, Juan Carlos; Suárez García, María JesúsSimple Summary: Following tooth loosening due to periodontal disease, caries, trauma, or tumoral processes, bone resorption and remodeling of the alveolar ridge makes the insertion of implants difficult. A number of bone augmentation techniques are available to treat atrophic jaws. However, when posterior bone is lacking and extensive bone augmentation surgeries are rejected by the patient, placing distally tilted posterior implants may offer a valid therapeutic option for implant-supported restorations. This treatment modality places the implants in preexisting bone, improving bone anchorage and prosthetic support. Nevertheless, some studies suggest that for tilted implants, bending moments are greater at the level of the angled abutment. Abstract: The aim of this study was to assess the long-term clinical behavior of straight implants in comparison with intentionally tilted dental implants (ITDI) supporting fixed restorations in partial or total edentulous arches, analyzing implant survival and success rates, complications, and marginal bone loss (MBL) after >5 years of function. An electronic search was conducted in five electronic databases (MEDLINE/Pubmed, Embase, Web of Science, Scopus, and Cochrane Central Register of Controlled Trials) supplemented by a manual search. The electronic and manual search identified 1853 articles, of which 8 articles were selected for analysis. Out of a total of 3987 dental implants, 2036 were axial dental implants and 1951 tilted. Similar results were found in implant survival or overall implant success rates. Moreover, no statistically significant differences were found in MBL (p = 0.369; MD 0.116 mm (−0.137; 0.369) 95% CI) The prosthodontic/biological complications reported in the articles were very diverse and irregularly distributed. This systematic review suggests that there is no difference between tilted compared with straight dental implants in the medium-long term (>5 years). However, further research is needed to generate long-term data and confirm the present review’s findings.Item The Fetal Origin of the Human Chin(Evolutionary Biology, 2017) Coquerelle, Michael; Rojo, Rosa; Drake, Abby Grace; Mitteroecker, Philipp; Prados Frutos, Juan Carlos; Murillo González, Jorge AlfonsoThe chin prominence is a hallmark of the modern human face and bears on its labial surface an inverted-T bony relief. Evolutionarily, whether the human chin is an adaptation for mastication or speech is debated but there is little compelling data supporting either claim. Furthermore, some suggest that the inverted-T relief is more important for phylogenetic inference than the chin prominence. However, there is no evidence for the developmental independence of the inverted-T relief and chin prominence. This debate requires empirical data on fetal development of the human chin. Using 3D imaging of the musculo-cervico-craniofacial skeleton of human fetuses and geometric morphometric methods, we discovered a developmental sequence leading to a chin prominence during early fetal development that is very similar to that which we previously observed in postnatal modern humans and in chimpanzee fetuses. Furthermore, we provide the evidence that the inverted-T relief is developmentally integrated with the chin prominence. The evolution of the human chin is constrained by cervico-craniofacial developmental that maintain an unobstructed fetal airway. Finally, the inverted T-relief should be neither treated independently from the chin prominence in phylogenetic analysis, nor is it a relevant taxonomic trait that defines the symphysis of modern humans.