Person:
Belda Hofheinz, Sylvia María

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First Name
Sylvia María
Last Name
Belda Hofheinz
URI
https://hdl.handle.net/20.500.14352/79193
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Medicina
Department
Salud Pública y Materno-Infantil
Area
Pediatría
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2023 - 20242
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Now showing 1 - 2 of 2
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    Pacientes pediátricos en ECMO: características clínicas, evolución y transporte primario
    (2024) Belda Hofheinz, Sylvia María; Rojo Conejo, Pablo
    Introducción: La ECMO se utiliza en pacientes críticamente enfermos y constituye una técnica muy invasiva, por lo que el manejo de estos pacientes supone un importante reto. Objetivos: Identificar factores de riesgo asociados al desarrollo de infecciones en los pacientes asistidos en ECMO. Revisar la intervención nutricional realizada en una cohorte prospectiva de pacientes en ECMO. Describir la primera experiencia nacional con un programa de transporte primario en ECMO durante 10 años y los primeros 5 transportes en ECMO pediátricos de pacientes afectos de patología por COVID en Europa. Material y métodos: Revisiones retrospectivas y prospectivas de cohortes de pacientes en ECMO...
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    Characteristics and management of patients with SARS‐CoV2 infection admitted to pediatric intensive care units: Data analysis of the Spanish national multicenter registry
    (Pediatric Pulmonology, 2023) Slöcker Barrio, María; Belda Hofheinz, Sylvia María; González Cortés, Rafael
    Introduction The purpose of this study is to describe the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) disease characteristics and management in children admitted to the pediatric intensive care units (PICU). Methods The present study was based on a national multicentric prospective registry including PICU patients with SARS-CoV2 infection or symptoms of multisystem inflammatory syndrome in children (MIS-C). Results A total of 298 patients were admitted to 41 different Spanish PICUs. A total of 76% of them were previously healthy. The most frequent manifestation was MIS-C (69.8%). On admission, 59.4% of patients did not have respiratory distress, and only 17.4% needed conventional mechanical ventilation (MV). The need for MV was associated with age (incidence rate ratios [IRR] 1.21, p < .012), pediatric sequential organ failure assessment score (p-SOFA) Score (IRR 1.12, p = .001), and need for transfusion (IRR 4.5, p < .004) in MIS-C patients, and with vasoactive drug use (IRR 2.73, p = .022) and the diagnosis of acute respiratory distress syndrome (IRR 2.83, p = .018) in patients admitted for other reasons. During the first day of admission, 56% of patients met shock criteria and 50.7% needed vasoactive drugs. In MIS-C patients, their use was associated with higher p-SOFA score (IRR 1.06, p < .001) and with the diagnosis of shock (IRR 5.78, p < .001). In patients without MIS-C, it was associated with higher p-SOFA score (IRR 1.05, p = .022). The mortality rate was 3%, being lower in MIS-C patients compared to patients admitted for other reasons (0.5% vs. 9.4%, p < .001). It was also lower in previously healthy patients compared to patients with previous comorbidities (0.9% vs. 9.7%, p < .001). Conclusions Severe SARS-CoV2 infection is uncommon in the pediatric population. In our series, respiratory distress was rare, being MIS-C the most frequent cause of PICU admission related to SARS-CoV2. In most cases, the course of the disease was mild except in children with previous diseases.