Person:
Zuluaga Arias, María Del Pilar

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First Name
María Del Pilar
Last Name
Zuluaga Arias
URI
https://hdl.handle.net/20.500.14352/79459
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Medicina
Department
Estadística e Investigación Operativa
Area
Estadística e Investigación Operativa
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2018 - 20192
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Now showing 1 - 2 of 2
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    The Impact of Adult ADHD in the Quality of Life Profile
    (Journal of Attention Disorders, 2019) Quintero Gutiérrez Del Álamo, Francisco Javier; Morales, Isabel; Vera, Rosa; Zuluaga Arias, María Del Pilar; Fernández Lucas, Alberto Amable
    In this multicenter, cross-sectional study, we aimed to investigate the quality of life (QoL) and the neuropsychological and clinical characteristics of adults with ADHD with different developmental pathways. Method: Our study sample included 25 control (healthy) participants, 31 patients with newly diagnosed ADHD without comorbidities (ADHD-C-D), 31 with newly diagnosed ADHD with comorbidities (ADHD+C-D), and 29 with previously diagnosed ADHD with comorbidities (ADHD+C+D). Results: Compared with controls, ADHDs had little differences in the attentional performance but showed higher impulsivity, more severe symptoms of depression and anxiety, and lower QoL. The ADHD+C-D group showed more severe symptoms of depression and anxiety than the ADHD+C+D group (p = .037 and p = .008, respectively), and poorer QoL in the psychological health sphere (p = .003). Conclusion: Differences between ADHD and control subjects were particularly remarkable in mood symptoms and QoL. Previous diagnosis might have a positive impact on mood symptoms and QoL in ADHD adults
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    Physical activity effects on the individual alpha peak frequency of older adults with and without genetic risk factors for Alzheimer’s Disease: A MEG study
    (Clinical Neurophysiology, 2018) De Frutos Lucas, Jaisalmer; López Sanz, David; Zuluaga Arias, María Del Pilar; Rodríguez Rojo, Inmaculada Concepción; Cazorla Luna, Raúl; López García, María Eugenia; Delgado Losada, María Luisa; Marcos Dolado, Alberto; Barabash Bustelo, Ana; López Sánchez, Ramón; Maestu Unturbe, Fernando; Fernández Lucas, Alberto Amable
    Objective Since a cure for Alzheimer’s Disease (AD) is yet to be discovered, attention has shifted towards prevention. Physical activity (PA) emerged as a notorious lifestyle factor that could influence brain structure and function. The individual alpha peak frequency (IAPF) is a measure that summarizes the spectral content of brain signals and has been proven to be sensitive to both AD pathology and PA interventions. Therefore, our goal was to unravel whether chronic PA modulates IAPF and if APOE ɛ4 carriage moderates this relationship. Methods We analyzed 4-minutes of resting-state magnetoencephalographic recordings from 100 healthy elders that provided self-reported measures of PA, and the IAPF was calculated. Results We found that IAPF was negatively influenced by age and APOE and positively influenced by PA. The effect of PA on IAPF only remained significant for the ɛ4 non-carriers group. Conclusions PA is positively associated to higher IAPF in healthy older adults and could potentially act as a protective factor against cognitive decline. Nevertheless, such effect is non-significant among elders who are more vulnerable to developing AD due to their genetic carriage. Significance This investigation offers the first neurophysiological evidences on the combined effects of APOE genotype and PA in healthy elders.