Person: Santos Bueso, Enrique Miguel
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First Name
Enrique Miguel
Last Name
Santos Bueso
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Óptica y Optometría
Department
Inmunología, Oftalmología y ORL
Area
Oftalmología
Identifiers
6 results
Search Results
Now showing 1 - 6 of 6
Item Corneal Segmentation Analysis Increases Glaucoma Diagnostic Ability of Optic Nerve Head Examination, Heidelberg Retina Tomograph's Moorfield's Regression Analysis, and Glaucoma Probability Score(Journal of Ophthalmology, 2015) Sáenz Francés, Federico; Jañez Escalada, Luis; Berrozpe Villabona, Clara; Borrego Sanz, Lara; Morales Fernández, Laura; Acebal Montero, Alejandra; Méndez Hernández, Carmen D.; Martínez De La Casa Fernández-Borrella, José María; Santos Bueso, Enrique Miguel; García Sánchez, Julián; García Feijoo, JuliánPurpose. To study whether a corneal thickness segmentation model, consisting in a central circular zone of 1 mm radius centered at the corneal apex (zone I) and five concentric rings of 1 mm width (moving outwards: zones II to VI), could boost the diagnostic accuracy of Heidelberg Retina Tomograph's (HRT's) MRA and GPS. Material and Methods. Cross-sectional study. 121 healthy volunteers and 125 patients with primary open-angle glaucoma. Six binary multivariate logistic regression models were constructed (MOD-A1, MOD-A2, MOD-B1, MOD-B2, MOD-C1, and MOD-C2). The dependent variable was the presence of glaucoma. In MOD-A1, the predictor was the result (presence of glaucoma) of the analysis of the stereophotography of the optic nerve head (ONH). In MOD-B1 and MOD-C1, the predictor was the result of the MRA and GPS, respectively. In MOD-B2 and MOD-C2, the predictors were the same along with corneal variables: central, overall, and zones I to VI thicknesses. This scheme was reproduced for model MOD-A2 (stereophotography along with corneal variables). Models were compared using the area under the receiver operator characteristic curve (AUC). Results. MOD-A1-AUC: 0.771; MOD-A2-AUC: 0.88; MOD-B1-AUC: 0.736; MOD-B2-AUC: 0.845; MOD-C1-AUC: 0.712; MOD-C2-AUC: 0.838. Conclusion. Corneal thickness variables enhance ONH assessment and HRT's MRA and GPS diagnostic capacity.Item Correlations between corneal and optic nerve head variables in healthy subjects and patients with primary open angle glaucoma(International journal of ophthalmology, 2015) Sáenz Francés, Federico; Jañez Escalada, Luis; Borrego Sanz, Lara; Berrozpe Villabona, Clara; Martínez De La Casa Fernández-Borrella, José María; Morales Fernández, Laura; García Sánchez, Julián; Santos Bueso, Enrique Miguel; García Feijoo, JuliánAIM: To correlate corneal variables (determined using the Pentacam) with optic nerve head (ONH) variables determined using the Heidelberg retina tomograph (HRT) in healthy subjects and patients diagnosed with primary open angle glaucoma (POAG). METHODS: Measurements were made in 75 healthy eyes and 73 eyes with POAG and correlations examined through Pearson correlation coefficients between the two sets of variables in the two subject groups. The corneal variables determined were corneal volume (CVol), central corneal thickness (CCT), overall corneal thickness (OvCT), the mean thickness of a circular zone centered at the corneal apex of 1 mm radius (zone I) and the mean thickness of several concentric rings, also centered at the apex until the limbus, each of 1 mm width (zones II to VI respectively). The ONH variables were determined using the HRT. RESULTS: The following pairs of variables were correlated in the control group: CCT-disc area (DAr) (-0.48; P<0.0001), Zone I-DAr (-0.503; P<0.0001) and Zone II-DAr (-0.443; P<0.0001); and in the POAG group: CCT-cup-to-disc area ratio (CDRa) (-0.402; P<0.0001), Zone I-CDRa (-0.418; P<0.0001), Zone II-CDRa (-0.405; P=0.006), Zone I-cup shape measure (CSM) (-0.415; P=0.002), Zone II-CSM (-0.405; P=0.001), Zone IV-height variation contour (HVC) (0.378; P=0.002); Zone V-HVC (0.388, P<0.0001). CONCLUSION: AS-OCT-derived lens thickness measurement is valid and comparable to the results obtained by A-scan US. It can be used as a reliable noncontact method for measuring lens thickness in adults with or without significant cataract.Item Cumplimiento del tratamiento del glaucoma(Archivos de la Sociedad Española de Oftalmología, 2014) Santos Bueso, Enrique Miguel; Sáenz Francés, Federico; García Sáenz, Sofía; Méndez Hernández, Carmen D.; Fernández Vidal, Ana M.; Morales Fernández, Laura; Martín Valdizán, Carmen; Martínez De La Casa Fernández-Borrella, José María; García Feijoo, Julián; García Sánchez, JuliánItem Cese paradójico de un caso de síndrome de Charles Bonnet(Archivos de la Sociedad Española de Oftalmología, 2014) Santos Bueso, Enrique Miguel; Serrador García, Mercedes; Sáenz Francés, Federico; Méndez Hernández, Carmen Dora; Martínez De La Casa Fernández-Borrella, José María; García Feijoo, Julián; García Sánchez, JuliánCaso clínico: paciente varón de 78 años diagnosticado de síndrome de Charles Bonnet (SCB) por déficit visual secundario a glaucoma terminal. Evolucionó a amaurosis, presentando desaparición brusca de las alucinaciones de forma paralela a la pérdida del resto visual. Discusión: el cese paradójico del SCB se produce cuando el paciente pierde el resto visual, evolucionando a amaurosis. La falta de estimulación en la retina y el córtex correspondiente hacen desaparecer las alucinaciones debido a que las neuronas desaferentadas e hiperexcitadas pierden el estímulo que desencadena el SCB.Item Hipertensión arterial secundaria a tratamiento con latanoprost(Archivos de la Sociedad Española de Oftalmología, 2015) Santos Bueso, Enrique Miguel; Sáenz Francés, Federico; Palmero Fernández, Laura; García Sáenz, Sofía; Martínez De La Casa Fernández-Borrella, José María; García Feijoo, Julián; García Sánchez, JuliánCaso clínico: mujer de 80 años intervenida mediante trabeculectomía por glaucoma primario de ángulo abierto en la que, debido al incremento tensional, se inició tratamiento con latanoprost. La monitorización de la tensión arterial (TA) demostró un incremento estadísticamente significativo de la TA tanto sistólica como diastólica coincidiendo con el uso del hipotensor tópico, que se resolvió al suspender voluntariamente el tratamiento, volviendo a elevarse al reintroducir la prostaglandina. Discusión: los análogos de las prostaglandinas disminuyen la presión intraocular al producir vasodilatación de las arterias ciliares y epiesclerales, aumentando el drenaje del humor acuoso. Los efectos cardiovasculares son poco frecuentes pero se han descrito por el efecto vasoconstrictor que puede desencadenarse como el incremento reversible de la TA de este caso.Item Prevalence and clinical characteristics of Charles Bonnet syndrome in Madrid, Spain(European Journal of Ophthalmology, 2014) Santos Bueso, Enrique Miguel; Sáenz Francés, Federico; Serrador García, Mercedes; Porta Etessam, Jesús; Martínez De La Casa Fernández-Borrella, José María; García Feijoo, Julián; García Sánchez, JuliánPurpose: Charles Bonnet syndrome (CBS) is a condition characterized by development of visual hallucinations in patients with no cognitive impairment and significant loss of vision mainly caused by age-related macular degeneration (AMD) or glaucoma. Methods: This was a study of prevalence and characteristics of CBS diagnosed at the Neuroophthalmic Unit within the Ophthalmology Department of Hospital Clínico San Carlos (HCSC), Madrid, Spain. Results: The CBS prevalence in patients from HCSC Madrid is 0.47%, rising to 15% in patients with low vision. Women over 80 years of age comprised 58.3% of the patients, who mainly had AMD (58.3%). Main characteristics of hallucinations included animals (50%), color (58.3%), moving (75%), 6- to 12-month evolution (50%), three times a day frequency (75%), and 3- to 5-minute duration (50%). Conclusions: Charles Bonnet syndrome is a complex process that must be treated jointly by ophthalmologists, neurologists, and psychiatrists in order to ensure accurate diagnosis and adequate management. New studies are needed in order to improve awareness of clinical manifestation of this condition, the incidence of which is underestimated due to patients' fear of being branded mentally ill, as well as physicians' lack of knowledge about CBS.