Person: Pérez Martín, Tania
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First Name
Tania
Last Name
Pérez Martín
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Odontología
Department
Especialidades Clínicas Odontológicas
Area
Estomatología
Identifiers
4 results
Search Results
Now showing 1 - 4 of 4
Item Clinical and microbiological effects of the use of a cetylpyridinium chloride dentifrice and mouth rinse in orthodontic patients: a 3-month randomized clinical trial(European Journal of Orthodontics, 2018) Herrera González, David; Escudero, Nayra; Pérez, Leire; Otheo, María; Cañete-Sánchez, Elena; Pérez Martín, Tania; Alonso Álvarez, Bettina María; Serrano, Jorge; Palma Fernández, Juan Carlos; Sanz Alonso, Mariano; Martín, ConchitaObjective: To assess the clinical, microbiological, and patient-based effects of using a cetylpyridinium chloride (CPC) toothpaste and mouth rinse in orthodontic patients. Design: Parallel randomized controlled, triple-blinded trial (participants, examiners, outcomes' assessors). A computer-generated list was used to allocate treatments. Central allocation was used for concealment. Participants: Thirty-one placebo (10 males, 21 females; mean age 15.2 ± 2.1) and 32 test patients (15 males, 17 females; mean age 15.0 ± 1.8) with fixed orthodontic appliance were included in the study. Interventions: Patients were randomly assigned to both brush and rinse with placebo or with CPC-based products. Products were purposely prepared in white opaque bottles. After screening and professional prophylaxis, patients received a baseline examination, and started to use the assigned products. Patients were monthly assessed during a 3-month period. Main outcome measures: Plaque (PlI) and gingival (GI) indexes. Secondary outcome variables: Calculus index, tooth staining, subgingival microbiological samples, patient-based variables (questionnaire, compliance, and remaining mouth rinse), side-effects (debonded braces or mucosal injuries). Results: Sixty-three patients were randomized, 13 patients were excluded from analysis because of early dropout, leaving 50 patients for intention to treat analysis. PlI in the upper jaw diminished (0.18; SD = 0.82) after 1 month in the test group, while it increased (0.26; SD = 0.62) in the placebo group (P = 0.024). Statistically significant higher GI values were observed in the placebo group at 1 month (mean increase = 0.05; SD = 0.33 versus mean decrease = 0.03; SD = 0.38) and 3 months (mean = 0.05; SD = 0.43 versus mean = 0.02; SD = 0.34). The taste of the test product was rated higher than the placebo at 2- and 3-month visits (P < 0.05). Non-significant changes were observed in microbiological parameters, overgrowth of opportunistic species or remaining secondary outcome variables, including side-effects. Conclusion: The use of CPC-based toothpaste and mouth rinse in orthodontic patients had limited effect in reducing plaque accumulation and gingival inflammation. Effects were little and highly variable. The use of the test products was not associated with relevant adverse effects.Item Clinical and microbiological effects of the use of a cetylpiridinium chloride dentifrice and mouth rinse in orthodonctic patiens: a 3 month randomized clinical trial(European Journal of Orthodontics, 2018) Herrera González, David; Escudero Nayra; Pérez Leire; Otheo María; Cañete-Sánchez Elena; Pérez Martín, Tania; Alonso Álvarez, Bettina María; Serrano Jorge; Palma Fernández, Juan Carlos; Sanz Alonso, Mariano; Martín Álvaro, María ConcepciónObjective: To assess the clinical, microbiological, and patient-based effects of using a cetylpyridinium chloride (CPC) toothpaste and mouth rinse in orthodontic patients. Design: Parallel randomized controlled, triple-blinded trial (participants, examiners, outcomes' assessors). A computer-generated list was used to allocate treatments. Central allocation was used for concealment. Participants: Thirty-one placebo (10 males, 21 females; mean age 15.2 ± 2.1) and 32 test patients (15 males, 17 females; mean age 15.0 ± 1.8) with fixed orthodontic appliance were included in the study. Interventions: Patients were randomly assigned to both brush and rinse with placebo or with CPC-based products. Products were purposely prepared in white opaque bottles. After screening and professional prophylaxis, patients received a baseline examination, and started to use the assigned products. Patients were monthly assessed during a 3-month period. Main outcome measures: Plaque (PlI) and gingival (GI) indexes. Secondary outcome variables: Calculus index, tooth staining, subgingival microbiological samples, patient-based variables (questionnaire, compliance, and remaining mouth rinse), side-effects (debonded braces or mucosal injuries). Results: Sixty-three patients were randomized, 13 patients were excluded from analysis because of early dropout, leaving 50 patients for intention to treat analysis. PlI in the upper jaw diminished (0.18; SD = 0.82) after 1 month in the test group, while it increased (0.26; SD = 0.62) in the placebo group (P = 0.024). Statistically significant higher GI values were observed in the placebo group at 1 month (mean increase = 0.05; SD = 0.33 versus mean decrease = 0.03; SD = 0.38) and 3 months (mean = 0.05; SD = 0.43 versus mean = 0.02; SD = 0.34). The taste of the test product was rated higher than the placebo at 2- and 3-month visits (P < 0.05). Non-significant changes were observed in microbiological parameters, overgrowth of opportunistic species or remaining secondary outcome variables, including side-effects. Conclusion: The use of CPC-based toothpaste and mouth rinse in orthodontic patients had limited effect in reducing plaque accumulation and gingival inflammation. Effects were little and highly variable. The use of the test products was not associated with relevant adverse effects.Item Eficacia y posibles efectos adversos del cloruro de cetilpiridinio en pacientes jóvenes portadores de aparatología fija ortodóncica(2015) Pérez Martín, Tania; Martín Álvaro, Mª Concepción; Herrera González, David; Alonso Álvarez, Bettina MaríaEl tratamiento de ortodoncia es frecuente en pacientes jóvenes por su elevada prevalencia de maloclusión. La aparatología fija en la cavidad oral favorece el acúmulo de placa bacteriana, con el riesgo de desarrollo de caries y gingivitis. Una estrategia complementaria al cepillado en estos pacientes es el uso de agentes antimicrobianos. El cloruro de cetilpiridinio (CPC) ha demostrado ser reductor de la formación de placa y gingivitis. El objetivo de este estudio fue evaluar la eficacia clínica y microbiológica del CPC al 0,05 por ciento en pasta y colutorio en pacientes portadores de ortodoncia fija, sus posibles efectos adversos y percepción subjetiva del producto. En este estudio clínico a 3 meses, aleatorio y doble ciego, se asignaron 32 pacientes al grupo test (B) y 31 al grupo placebo (A). El grupo B utilizó 2 veces al día un enjuague y pasta con CPC, y el grupo A utilizó los mismos productos sin el agente activo. Cada mes se registraron índices de placa (IP) y gingivitis (IG), se tomaron muestras microbiológicas subgingivales en las visita basal y final, cada mes se registraron intensidad y área de tinción, y respuestas a un cuestionario. Se observaron valores de IG significativamente mayores en el grupo A en los meses 1 y 3. El IP disminuyó en el grupo B a 1 mes, existiendo diferencias estadísticamente significativas con el grupo A. No hubo diferencias en los parámetros microbiológicos, ni se detectó sobrecrecimiento de especies oportunistas. Fue mejor el sabor del producto test a 2 y 3 meses. No hubo diferencias entre grupos en los posibles efectos adversos. El uso de pasta y colutorio con CPC al 0,05 por ciento en pacientes jóvenes portadores de aparatología fija ortodóncica fue eficiente en la reducción de placa y gingivitis, no presentó efectos adversos asociados, y a los pacientes les gusto su sabor.- Project number: PIMCD255/23-24
Item Aplicación a la docencia de herramientas de Inteligencia Artificial (IA) para la evaluación de la calidad de publicaciones científicas en Epidemiología(2024) Jiménez García, Rodrigo; Barrio Fernández, José Luis del; Blasco Jiménez, Carmen; Jiménez Sierra, Lucía; López De Andrés, Ana Isabel; Pérez Martín, Tania; Valdés López-Linares, Sergio; Zamorano León, José Javier; Jiménez García, Rodrigo