Person: Martínez González, Miguel Ángel
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First Name
Miguel Ángel
Last Name
Martínez González
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Medicina
Department
Area
Anatomía Patológica
Identifiers
3 results
Search Results
Now showing 1 - 3 of 3
Item Adopting a High-Polyphenolic Diet Is Associated with an Improved Glucose Profile: Prospective Analysis within the PREDIMED-Plus Trial(Antioxidants, 2022) Tresserra Rimbau, Anna; Castro Barquero, Sara; Becerra Tomás, Nerea; Babio, Nancy; Martínez González, Miguel Ángel; Corella, Dolores; Fitó, Montserrat; Romaguera, Dora; Vioque, Jesús; Alonso Gómez, Ángel M.; Wärnberg, Julia; Martínez, José Alfredo; Serra Majem, Luís; Estruch, Ramon; Tinahones, Francisco J.; Lapetra, José; Pintó, Xavier; Tur, Josep A.; López Miranda, José; Cano Ibáñez, Naomi; Delgado Rodríguez, Miguel; Matía Martín, Pilar; Daimiel, Lidia; Martín Sánchez, Vicente; Vidal, Josep; Vázquez, Clotilde; Ros, Emilio; Basterra, Francisco Javier; Fernández de la Puente, María; Asensio, Eva María; Castañer, Olga; Bullón Vela, Vanessa; Tojal Sierra, Lucas; Gómez Gracia, Enrique; Cases Pérez, Eugenio; Konieczna, Jadwiga; García Ríos, Antonio; Casañas Quintana, Tamara; Bernal López, María Rosa; Santos Lozano, José Manuel; Esteve Luque, Virginia; Bouzas, Cristina; Vázquez Ruiz, Zenaida; Palau Galindo, Antoni; Barragan, Rocio; López Grau, Mercè; Razquín, Cristina; Goicolea Güemez, Leire; Toledo, Estefanía; Vergaz, Manel Vila; Lamuela Raventós, Rosa María; Salas Salvadó, JordiPrevious studies suggested that dietary polyphenols could reduce the incidence and complications of type-2 diabetes (T2D); although the evidence is still limited and inconsistent. This work analyzes whether changing to a diet with a higher polyphenolic content is associated with an improved glucose profile. At baseline, and at 1 year of follow-up visits, 5921 participants (mean age 65.0 ± 4.9, 48.2% women) who had overweight/obesity and metabolic syndrome filled out a validated 143-item semi-quantitative food frequency questionnaire (FFQ), from which polyphenol intakes were calculated. Energy-adjusted total polyphenols and subclasses were categorized in tertiles of changes. Linear mixed-effect models with random intercepts (the recruitment centers) were used to assess associations between changes in polyphenol subclasses intake and 1-year plasma glucose or glycosylated hemoglobin (HbA1c) levels. Increments in total polyphenol intake and some classes were inversely associated with better glucose levels and HbA1c after one year of follow-up. These associations were modified when the analyses were run considering diabetes status separately. To our knowledge, this is the first study to assess the relationship between changes in the intake of all polyphenolic groups and T2D-related parameters in a senior population with T2D or at high-risk of developing T2D.Item Use of Different Food Classification Systems to Assess the Association between Ultra-Processed Food Consumption and Cardiometabolic Health in an Elderly Population with Metabolic Syndrome (PREDIMED-Plus Cohort)(Nutrients, 2021) Martínez Pérez, Celia; San Cristobal, Rodrigo; Guallar Castillon, Pilar; Martínez González, Miguel Ángel; Salas Salvadó, Jordi; Corella, Dolores; Castañer, Olga; Martínez, José Alfredo; Alonso Gómez, Ángel M.; Wärnberg, Julia; Vioque, Jesús; Romaguera, Dora; López Miranda, José; Estruch, Ramon; Tinahones, Francisco J.; Lapetra, José; Serra-Majem, Lluis; Bueno Cavanillas, Aurora; Tur, Josep A.; Sánchez, Vicente Martín; Pintó, Xavier; Gaforio, José J.; Matía Martín, Pilar; Vidal, Josep; Vázquez, Clotilde; Ros, Emilio; Bes Rastrollo, Maira; Babio, Nancy; Sorlí, Jose V.; Lassale, Camille; Pérez Sanz, Beatriz; Vaquero Luna, Jessica; Bazán, María Julia Ajejas; Barceló Iglesias, María Concepción; Konieczna, Jadwiga; Ríos, Antonio García; Bernal López, María Rosa; Santos Lozano, José Manuel; Toledo, Estefanía; Becerra Tomás, Nerea; Portoles, Olga; Zomeño, María Dolores; Abete, Itziar; Moreno Rodríguez, Anai; Lecea Juarez, Oscar; Nishi, Stephanie K.; Muñoz Martínez, Júlia; Ordovás, José M.; Daimiel, LidiaThe association between ultra-processed food (UPF) and risk of cardiometabolic disorders is an ongoing concern. Different food processing-based classification systems have originated discrepancies in the conclusions among studies. To test whether the association between UPF consumption and cardiometabolic markers changes with the classification system, we used baseline data from 5636 participants (48.5% female and 51.5% male, mean age 65.1 ± 4.9) of the PREDIMED-Plus (“PREvention with MEDiterranean DIet”) trial. Subjects presented with overweight or obesity and met at least three metabolic syndrome (MetS) criteria. Food consumption was classified using a 143-item food frequency questionnaire according to four food processing-based classifications: NOVA, International Agency for Research on Cancer (IARC), International Food Information Council (IFIC) and University of North Carolina (UNC). Mean changes in nutritional and cardiometabolic markers were assessed according to quintiles of UPF consumption for each system. The association between UPF consumption and cardiometabolic markers was assessed using linear regression analysis. The concordance of the different classifications was assessed with intra-class correlation coefficients (ICC3, overall = 0.51). The highest UPF consumption was obtained with the IARC classification (45.9%) and the lowest with NOVA (7.9%). Subjects with high UPF consumption showed a poor dietary profile. We detected a direct association between UPF consumption and BMI (p = 0.001) when using the NOVA system, and with systolic (p = 0.018) and diastolic (p = 0.042) blood pressure when using the UNC system. Food classification methodologies markedly influenced the association between UPF consumption and cardiometabolic risk markers.Item Variety in fruits and vegetables, diet quality and lifestyle in an older adult Mediterranean population(Clinical Nutrition, 2021) López González, Leyre; Becerra Tomás, Nerea; Babio Nancy; Martínez González, Miguel Ángel; Díaz López, Andrés; Corella, Dolores; Goday, Albert; Romaguera, Dora; Vioque, Jesús; Alonso Gómez, Ángel M.; Wärnberg, Julia; Martínez, J. Alfredo; Serra Majem, Luis; Estruch, Ramón; Tinahones, Francisco; Lapetra, José; Pintó, Xavier; Tur, Josep A.; López Miranda, José; Bueno Cavanillas, Aurora; Delgado Rodríguez, Miguel; Matía Martín, María Del Pilar; Daimiel, Lidia; Álvarez Álvarez, Laura; Vidal, Josep; Vázquez, Clotilde; Ros, Emilio; Vázquez Ruiz, Zenaida; Canudas, Silvia; Fernández Carrión, Rebeca; Castañer, Olga; Zulet, M. Ángeles; Tojal Sierra, Lucas; Ajejas Bazán, María Julia; Carmen M. López García; Martín, Marian; García Ríos, Antonio; Casas, Rosa; Gómez Pérez, Ana M.; Santos Lozano, José Manuel; Goñi, Estíbaliz; Guillem Saiz, Patricia; Lassale, Camile; Abete, Itziar; Salaverria Lete, Itziar; Eguaras, Sonia; Schröder, Helmut; Salas Salvadó, JordiSummary Background and aims Previous studies, mainly focused on quantity rather than variety, have shown beneficial associations between the amount of fruit and vegetable consumed, diet quality and healthy lifestyle. The aim is to evaluate the association between fruit and vegetable consumption, diet quality and lifestyle in an elderly Mediterranean population, considering both variety and the combination of quantity and variety (QV). Methods A cross-sectional analysis of 6647 participants (51.6% of males) was conducted in the framework of the PREDIMED-Plus study. A variety score was created as the sum of vegetables and/or fruits consumed at least once per month using food frequency questionnaires. Dietary Reference Intakes (EAR and IA values) were used to estimate the prevalence of inadequate intake of dietary fiber and micronutrients. Logistic regression models were performed to examine the association between fruit and vegetable consumption and not meeting the DRIs, by tertiles of fruit and vegetable variety and QV categories. Results Participants with higher fruit and vegetable variety score reported a significant higher intake of fiber, vitamins, minerals and flavonoids and were significantly more likely to be physically active and non-smoker. Besides, higher variety in fruit and vegetable consumption was associated with lower prevalence of having an inadequate intake of fiber [(0.13 (0.11–0.16)], two or more [(0.17 (0.14–0.21)], three or more [(0.15 (0.13–0.18)] and four or more [(0.11 (0.10–0.14)] micronutrients in our participants. Higher quantity and variety in fruit and vegetable consumption was associated with lower prevalence of having an inadequate intake of fiber [(0.05 (0.04–0.06)], two or more [(0.08 (0.06–0.10)], three or more [(0.08 (0.06–0.09)] and four or more [(0.06 (0.05–0.07)] micronutrients. Conclusion Greater variety in fruit and vegetable intake was associated with better nutrient adequacy, diet quality and healthier lifestyle in an elderly Mediterranean population.