Person:
García García, Rosa María

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First Name
Rosa María
Last Name
García García
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Veterinaria
Department
Fisiología
Area
Fisiología
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2015 - 201922020 - 20211
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Now showing 1 - 3 of 3
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    Publication
    Effects of feed restriction during pregnancy on maternal reproductive outcome, foetal hepatic IGF gene expression and offspring performance in the rabbit
    (Elsevier, 2021-10-13) García García, Rosa María; Arias Álvarez, María; Rodríguez, M.; Sánchez Rodríguez, A.; Formoso Rafferty, N.; Lorenzo González, Pedro Luis; Rebollar, P.G.
    Primiparous female rabbits have high nutritional requirements and, while it is recommended that they are subjected to an extensive reproductive rhythm, this could lead to overweight, affecting reproductive outcomes. We hypothesised that restricting food intake during the less energetic period of gestation could improve reproductive outcome without impairing offspring viability. This study compares two groups of primiparous rabbit does in an extensive reproductive programme, one in which feed was restricted from Day 0 to Day 21 of gestation (R021), and another in which does were fed ad libitum (control) throughout pregnancy. The mother and offspring variables compared were (1) mother reproductive outcomes at the time points pre-implantation (Day 3 postartificial insemination [AI]), preterm (Day 28 post-AI) and birth; and (2) the prenatal offspring characteristic IGF system gene expression in foetal liver, liver fibrosis and foetus sex ratio, and postnatal factor viability and growth at birth, and survival and growth until weaning. Feed restriction did not affect the conception rate, embryo survival, or the number of morulae and blastocysts recovered at Day 3 post-AI. Preterm placenta size and efficiency were similar in the two groups. However, both implantation rate (P < 0.001) and the number of foetuses (P = 0.05) were higher in the R021 mothers than controls, while there was no difference in foetal viability. Foetal size and weight, the weights of most organs, organ weight/BW ratios and sex ratio were unaffected by feed restriction; these variables were only affected by uterine position (P < 0.05). Conversely, in the R021 does, foetal liver IGBP1 and IGF2 gene expression were dysregulated despite no liver fibrosis and a normal liver structure. No effects of restricted feed intake were produced on maternal fertility, prolificacy, or offspring birth weight, but control females weaned more kits. Litter weight and mortality rate during the lactation period were also unaffected. In conclusion, pre-implantation events and foetal development were unaffected by feed restriction. While some genes of the foetal hepatic IGF system were dysregulated during pregnancy, liver morphology appeared normal, and the growth of foetuses and kits until weaning was unmodified. This strategy of feed restriction in extensive reproductive rhythms seems to have no significant adverse effects on dam reproductive outcome or offspring growth and viability until weaning.
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    Publication
    Biotecnologías de la reproducción I: laboratorio virtual de producción de embriones
    (2015-07-28) Arias Álvarez, María; García García, Rosa María; Lorenzo González, Pedro Luis; García Rebollar, Pilar; Revuelta Rueda, Luis; González Gil, Alfredo
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    Publication
    Digitalización de documentos para generar recursos educativos virtuales
    (2017-06-28) Revuelta Rueda, Luis; García García, Rosa María; Arias Álvarez, María; Gonzalez Gil, Alfredo; Sanz Luengo, María del Mar; Sánchez rodríguez, Ana
    Las nuevas tecnologías y los medios digitales nos ofrecen nuevas posibilidades educativas: e-learning, entorno BYOD (Bring Your Own Device), etc. Los cursos abiertos (MOOCs) y los entornos de formación virtual (VLE) permiten el intercambio de contenido e información a través de diversos canales. Pero estos medios, por sí solos, no garantizan conseguir resultados de aprendizaje si no se cuentan con contenidos educativos adecuados. Estos modelos educativos no deben contar sólo con recursos “ex profeso” sino que deben apoyarse en materiales existentes de calidad, como libros de texto, artículos de revistas especializadas y fondos gráficos de los museos de la facultad. Sin embargo estos recursos no se encuentran en formato digital en nuestras bibliotecas aunque son muy demandados. La imposibilidad de hacer bases de datos de los documentos escaneados en la biblioteca, obliga al escaneo continuo de los ejemplares y por lo tanto sufren una manipulación por reutilización que puede afectar a su conservación. Así pues, la digitalización por escáner “cenital” es una solución útil para obtener contenidos digitales de documentos delicados o antiguos.