Person:
Díaz Valle, David

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First Name
David
Last Name
Díaz Valle
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Medicina
Department
Inmunología, Oftalmología y ORL
Area
Oftalmología
Identifiers
UCM identifierORCIDScopus Author IDDialnet ID

Search Results

Now showing 1 - 10 of 22
  • Publication
    Hipertensión intracraneal idiopática en paciente con malformación de Chiari tipo I
    (Elsevier España, 2015-04) Santos Bueso, Enrique; Porta-Etessam, Jesús; Díaz Valle, David; Benítez del Castillo, José Manuel; Gegúndez Fernández, José Antonio; Vinuesa Silva, Josefa María; García Sánchez, Julián
    Caso clínico: mujer de 22 años que consultó por cefalea y disminución de la visión. Presentaba papiledema asimétrico y, en las pruebas de imagen, un descenso amigdalar de 6mm, siendo diagnosticada de hipertensión intracraneal idiopática coincidente con una malformación de Chiari (MC). Discusión: la MC tipo I es la más frecuente de este grupo de malformaciones y se caracteriza por un descenso amigdalar superior a 5mm, pudiendo originar hipertensión intracraneal por el bloqueo del líquido cefalorraquídeo. En este caso la MC no fue la responsable de la hipertensión intracraneal, sino una casualidad al coincidir ambos procesos.
  • Publication
    Estudio morfológico y funcional del endotelio corneal tras la cirugía de la catarata
    (Universidad Complutense de Madrid, Servicio de Publicaciones, 2002) Díaz Valle, David; Benítez del Castillo, José Manuel
    Propósito: estudiar las alteraciones morfofuncionales inducidas en el endotelio corneal por la cirugía de la catarata con los principales métodos disponibles: paquimetría, fluorofotometría y microscopia especular.sujetos, material y metodos: Se ha estudiado una muestra homogénea de 98 pacientes con cataratas seniles no complicadas, realizando las determinaciones antes y tres meses después de la cirugía. Los pacientes se han clasificado en varios grupos atendiendo a la técnica quirúrgica (cirugía extracapsular con distintos tipos de capsulotomías: abrelatas, sonrisa y capsulorrexis y facoemulsificacion) y al grado de experiencia del cirujano. Resultados: existe una alteración significativa de la función de barrera endotelial a los 3 meses de la cirugía, así como una perdida celular media del 18'8+- 9'3%. Tanto la cirugía extracapsular como la facoemulsificación inducen un daño morfofuncional comparable, que es significativamente mayor en las intervenciones realizadas por cirujanos noveles. El mantenimiento de la cápsula anterior del cristalino en la capsulotomia en sonrisa hasta el final de la cirugía desempeña un papel de protección endotelial. No existe un incremento postoperatorio significativo del grosor corneal con ninguna de las técnicas.
  • Publication
    Comparison of the efficacy of topical insulin with autologous serum eye drops in persistent epithelial defects of the cornea
    (John Wiley & Sons Ltd., 2021-08-18) Díaz Valle, David; Burgos Blasco, Bárbara; Rego Lorca, Daniela; Puebla Garcia, Virginia; Pérez García, Pilar; Benítez del Castillo, José Manuel; Herrero Vanrell, Rocío; Vicario de la Torre, Marta; Gegúndez Fernández, José Antonio
    Purpose: To investigate the effect of topical insulin on epithelization in persistent epithelial defects (PED) refractory to usual treatment compared to autologous serum. Design: Retrospective, consecutive case–control series. Methods: The charts of 61 consecutive patients with PED treated with topical insulin (case group) and 23 treated with autologous serum (control group) were reviewed. Primary efficacy end points were the percentage of patients in which epithelization was achieved, as well as the rate and time until epithelization. Secondary efficacy point was need for amniotic membrane transplantation (AMT) or other surgeries. Results: Mean time between PED diagnosis and start of topical insulin was 22.7 � 18.5 days (range 13–115) and the mean area was 14.8 � 16.2 mm2 (range 1.1–70.6). In the control group, mean time was 27.9 � 16.8 days, mean epithelial defect area being 18.6 � 15.0 mm2 (range 1.7–52.9). No differences in baseline characteristics were found between groups (p > 0.05). Epithelization was achieved in 51 patients (84%) on insulin and 11 patients (48%) on autologous serum (p = 0.002). In those patients, mean time until reepithelization was 32.6 � 28.3 days (range 4–124) in the insulin group and 82.6 � 82.4 days (range 13–231) in the autologous serum group (p = 0.011). The need for AMT was significantly lower in the insulin group (p = 0.005). PED recurrence was higher in patients treated on autologous serum (43%) compared with insulin (11%) (p = 0.002). Conclusions: Topical insulin is an effective treatment and safely promotes healing of PED. In our series, topical insulin presented better epithelization outcomes than autologous serum and could thus be considered as a first-line treatment.
  • Publication
    Purpureocillium lilacinum fungal keratitis: Confocal microscopy diagnosis and histopathology correlation
    (Elsevier, 2020-12-01) Burgos Blasco, Bárbara; Gegúndez Fernández, José Antonio; Díaz Valle, David
  • Publication
    Effect of pharmacological pupil dilation on measurements and iol power calculation made using the new swept-source optical coherence tomography-based optical biometer
    (Elsevier, 2016-10-25) Arriola Villalobos, Pedro; Almendral Gómez, Jaime; Garzón Jiménez, Nuria; Ruiz-Medrano, Jorge; Fernández Pérez, Carlos; Martinez de la Casa, Jose Maria; Díaz Valle, David
    Purpose: to determine whether pupil dilation affects biometric measurements and intraocular lens (IOL) power calculation made using the new swept-source optical coherence tomography-based optical biometer (IOLMaster 700©; Carl Zeiss Meditec, Jena, Germany). Procedures: eighty-one eyes of 81 patients evaluated for cataract surgery were prospectively examined using the IOLMaster 700© before and after pupil dilation with tropicamide 1%. The measurements made were: axial length (AL), central corneal thickness (CCT), aqueous chamber depth (ACD), lens thickness (LT), mean keratometry (MK), white-to-white distance (WTW) and pupil diameter (PD). Holladay II and SRK/T formulas were used to calculate IOL power. Agreement between measurement modes (with and without dilation) was assessed through intraclass correlation coefficients (ICC) and Bland-Altman plots. Results: mean patient age was 75.17 ± 7.54 years (range: 57–92). Of the variables determined, CCT, ACD, LT and WTW varied significantly according to pupil dilation. Excellent intraobserver correlation was observed between measurements made before and after pupil dilation. Mean IOL power calculation using the Holladay 2 and SRK/T formulas were unmodified by pupil dilation. Conclusions: the use of pupil dilation produces statistical yet not clinically significant differences in some IOLMaster 700© measurements. However, it does not affect mean IOL power calculation.
  • Publication
    Metabolómica de la lágrima
    (Elsevier España, 2016-04) Muñóz Hernández, Ana María; Galbis Estrada, Carmen; Santos Bueso, Enrique; Cuiña Sardiña, Ricardo; Díaz Valle, David; Gegúndez Fernández, José Antonio; Pinazo Durán, Mª Dolores; Benítez del Castillo, José Manuel
  • Publication
    Novel Insights into the Transmission of SARS-CoV-2 Through the Ocular Surface and its Detection in Tears and Conjunctival Secretions: A Review
    (Springer Healthcare, 2020-08-18) Güemes Villahoz, Noemi; Burgos Blasco, Bárbara; Vidal Villegas, Beatriz; García Feijoo, Julián; Arriola Villalobos, Pedro; Martínez de la Casa, José María; Díaz Valle, David; Konstas, Anastasios Georgios
    SARS-CoV-2 is a highly transmissible virus that spreads mainly via person-to-person contact through respiratory droplets, or through contact with contaminated objects or surfaces from an infected person. At present we are passing through a phase of slow and painful understanding of the origin, epidemiological profile, clinical spectrum, and risk profile of the virus. To the best of our knowledge there is only limited and contradictory evidence concerning SARS-CoV-2 transmission through other routes. Importantly, the eye may constitute not only a potential site of virus replication but also an alternative transmission route of the virus from the ocular surface to the respiratory and gastrointestinal tract. It is therefore imperative to gain a better insight into the potential ophthalmological transmission route of the virus and establish directions on best practice and future models of care for ophthalmological patients. This review article critically evaluates available evidence on the ophthalmological mode of viral transmission and the value of earlier identification of the virus on the eye. More evidence is urgently needed to better evaluate the need for protective measures and reliable ocular diagnostic tests to diminish further pandemic spread.
  • Publication
    Agreement and clinical comparison between a new swept-source optical coherence tomography-based optical biometer and an optical low-coherence reflectometry biometer
    (Nature Publishing Group, 2017-03-01) Arriola Villalobos, Pedro; Almendral Gómez, Jaime; Garzón Jiménez, Nuria; Ruiz Medrano, Jorge; Fernández Pérez, Cristina; Martínez de la Casa, Jose Maria; Díaz Valle, David
    Purpose To compare measurements taken using a swept-source optical coherence tomography-based optical biometer (IOLmaster 700) and an optical low-coherence reflectometry biometer (Lenstar 900), and to determine the clinical impacts of differences in their measurements on intraocular lens (IOL) power predictions. Methods Eighty eyes of 80 patients scheduled to undergo cataract surgery were examined with both biometers. The measurements made using each device were axial length (AL), central corneal thickness (CCT), aqueous depth (AQD), lens thickness (LT), mean keratometry (MK), white-to-white distance (WTW), and pupil diameter (PD). Holladay 2 and SRK/T formulas were used to calculate IOL power. Differences in measurement between the two biometers were determined using the paired t-test. Agreement was assessed through intraclass correlation coefficients (ICC) and Bland-Altman plots. Results Mean patient age was 76.3±6.8 years (range 59-89). Using the Lenstar, AL and PD could not be measured in 12.5 and 5.25% of eyes, respectively, while IOLMaster 700 took all measurements in all eyes. The variables CCT, AQD, LT, and MK varied significantly between the two biometers. According to ICCs, correlation between measurements made with both devices was excellent except for WTW and PD. Using the SRK/T formula, IOL power prediction based on the data from the two devices were statistically different, but differences were not clinically significant. Conclusions No clinically relevant differences were detected between the biometers in terms of their measurements and IOL power predictions. Using the IOLMaster 700, it was easier to obtain biometric measurements in eyes with less transparent ocular media or longer AL.
  • Publication
    Conjunctivitis in an Individual With Monkeypox
    (American Medical Association, 2022-09-07) Ly-Yang, Fernando; Miranda Sánchez, Alfonso; Burgos Blasco, Bárbara; Fernández-Vigo, José Ignacio; Gegúndez Fernández, José Antonio; Díaz Valle, David
  • Publication
    Cuerpo extraño enclavado en iris después de cirugía de catarata
    (Elsevier España, 2016-03) Santos Bueso, Enrique; Jiménez Santos, M; Díaz Valle, David; Gegúndez Fernández, José Antonio; Cuiña Sardiña, Ricardo; Benítez del Castillo, José Manuel; García Sánchez, Julián
    Caso clínico: mujer de 75 años intervenida de catarata en ojo izquierdo, que presentaba a las 24h una agudeza visual de 0,8. En la biomicroscopia destacaba un cuerpo extraño anclado al iris en sector nasal coincidente con la incisión principal de la facoemulsificación, que fue retirado en un segundo acto quirúrgico. Fue analizado e informado como estructura inerte de naturaleza plástica. Discusión: planteamos el posible origen de la presencia del resto plástico en el postoperatorio de la cirugía de la catarata. En este caso su naturaleza inerte no desencadenó mayor inflamación intraocular. Además, la estructura rígida favoreció su anclaje al iris evitando otras complicaciones. Deben extremarse las medidas preventivas en la cirugía de la catarata revisando incluso los instrumentos y accesorios al terminar la cirugía.