Person:
Alonso Álvarez, Bettina María

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First Name
Bettina María
Last Name
Alonso Álvarez
URI
https://hdl.handle.net/20.500.14352/79844
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Odontología
Department
Especialidades Clínicas Odontológicas
Area
Estomatología
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Author: Sanz Alonso, Mariano ×

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Now showing 1 - 10 of 22
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    Clinical and microbiological effects of the use of a cetylpyridinium chloride dentifrice and mouth rinse in orthodontic patients: a 3-month randomized clinical trial
    (European Journal of Orthodontics, 2018) Herrera González, David; Escudero, Nayra; Pérez, Leire; Otheo, María; Cañete-Sánchez, Elena; Pérez Martín, Tania; Alonso Álvarez, Bettina María; Serrano, Jorge; Palma Fernández, Juan Carlos; Sanz Alonso, Mariano; Martín, Conchita
    Objective: To assess the clinical, microbiological, and patient-based effects of using a cetylpyridinium chloride (CPC) toothpaste and mouth rinse in orthodontic patients. Design: Parallel randomized controlled, triple-blinded trial (participants, examiners, outcomes' assessors). A computer-generated list was used to allocate treatments. Central allocation was used for concealment. Participants: Thirty-one placebo (10 males, 21 females; mean age 15.2 ± 2.1) and 32 test patients (15 males, 17 females; mean age 15.0 ± 1.8) with fixed orthodontic appliance were included in the study. Interventions: Patients were randomly assigned to both brush and rinse with placebo or with CPC-based products. Products were purposely prepared in white opaque bottles. After screening and professional prophylaxis, patients received a baseline examination, and started to use the assigned products. Patients were monthly assessed during a 3-month period. Main outcome measures: Plaque (PlI) and gingival (GI) indexes. Secondary outcome variables: Calculus index, tooth staining, subgingival microbiological samples, patient-based variables (questionnaire, compliance, and remaining mouth rinse), side-effects (debonded braces or mucosal injuries). Results: Sixty-three patients were randomized, 13 patients were excluded from analysis because of early dropout, leaving 50 patients for intention to treat analysis. PlI in the upper jaw diminished (0.18; SD = 0.82) after 1 month in the test group, while it increased (0.26; SD = 0.62) in the placebo group (P = 0.024). Statistically significant higher GI values were observed in the placebo group at 1 month (mean increase = 0.05; SD = 0.33 versus mean decrease = 0.03; SD = 0.38) and 3 months (mean = 0.05; SD = 0.43 versus mean = 0.02; SD = 0.34). The taste of the test product was rated higher than the placebo at 2- and 3-month visits (P < 0.05). Non-significant changes were observed in microbiological parameters, overgrowth of opportunistic species or remaining secondary outcome variables, including side-effects. Conclusion: The use of CPC-based toothpaste and mouth rinse in orthodontic patients had limited effect in reducing plaque accumulation and gingival inflammation. Effects were little and highly variable. The use of the test products was not associated with relevant adverse effects.
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    Project number: 63
    Cómo motivar al estudiante: Priming y B-learning
    (2017) Iniesta Albentosa, Margarita Isabel; Alonso Álvarez, Bettina María; Herrera González, David; Sanz Alonso, Mariano; Figuero Ruiz, Elena; Santa Cruz Astorgui, María Isabel; Legido Arce, Berta; Carrillo de Albornoz Sainz, Ana; Dolláguez Chamarro, Patricia
    Este proyecto pretende mejorar el rendimiento de los estudiantes, independientemente de su nivel de conocimientos y, a la vez, mejorar su motivación y su compromiso con la asignatura de Periodoncia. Para ello se construye una serie de actividades pre-clase adaptadas al nivel del 2º curso de Grado en Odontología.
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    Clinical and microbiological effects of the use of a cetylpiridinium chloride dentifrice and mouth rinse in orthodonctic patiens: a 3 month randomized clinical trial
    (European Journal of Orthodontics, 2018) Herrera González, David; Escudero Nayra; Pérez Leire; Otheo María; Cañete-Sánchez Elena; Pérez Martín, Tania; Alonso Álvarez, Bettina María; Serrano Jorge; Palma Fernández, Juan Carlos; Sanz Alonso, Mariano; Martín Álvaro, María Concepción
    Objective: To assess the clinical, microbiological, and patient-based effects of using a cetylpyridinium chloride (CPC) toothpaste and mouth rinse in orthodontic patients. Design: Parallel randomized controlled, triple-blinded trial (participants, examiners, outcomes' assessors). A computer-generated list was used to allocate treatments. Central allocation was used for concealment. Participants: Thirty-one placebo (10 males, 21 females; mean age 15.2 ± 2.1) and 32 test patients (15 males, 17 females; mean age 15.0 ± 1.8) with fixed orthodontic appliance were included in the study. Interventions: Patients were randomly assigned to both brush and rinse with placebo or with CPC-based products. Products were purposely prepared in white opaque bottles. After screening and professional prophylaxis, patients received a baseline examination, and started to use the assigned products. Patients were monthly assessed during a 3-month period. Main outcome measures: Plaque (PlI) and gingival (GI) indexes. Secondary outcome variables: Calculus index, tooth staining, subgingival microbiological samples, patient-based variables (questionnaire, compliance, and remaining mouth rinse), side-effects (debonded braces or mucosal injuries). Results: Sixty-three patients were randomized, 13 patients were excluded from analysis because of early dropout, leaving 50 patients for intention to treat analysis. PlI in the upper jaw diminished (0.18; SD = 0.82) after 1 month in the test group, while it increased (0.26; SD = 0.62) in the placebo group (P = 0.024). Statistically significant higher GI values were observed in the placebo group at 1 month (mean increase = 0.05; SD = 0.33 versus mean decrease = 0.03; SD = 0.38) and 3 months (mean = 0.05; SD = 0.43 versus mean = 0.02; SD = 0.34). The taste of the test product was rated higher than the placebo at 2- and 3-month visits (P < 0.05). Non-significant changes were observed in microbiological parameters, overgrowth of opportunistic species or remaining secondary outcome variables, including side-effects. Conclusion: The use of CPC-based toothpaste and mouth rinse in orthodontic patients had limited effect in reducing plaque accumulation and gingival inflammation. Effects were little and highly variable. The use of the test products was not associated with relevant adverse effects.
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    The Antimicrobial Activity of Curcumin and Xanthohumol on Bacterial Biofilms Developed over Dental Implant Surfaces
    (International Journal of Molecular Sciences, 2023) Alonso Español, Andrea; Bravo Fernández, Enrique; Ribeiro Vidal, Honorato José; Virto Ruiz, Leire; Herrera González, David; Alonso Álvarez, Bettina María; Sanz Alonso, Mariano
    In search for natural products with antimicrobial properties for use in the prevention and treatment of peri-implantitis, the purpose of this investigation was to evaluate the antimicrobial activity of curcumin and xanthohumol, using an in vitro multi-species dynamic biofilm model including Streptococcus oralis, Actinomyces naeslundii, Veillonella parvula, Fusobacterium nucleatum, Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans. The antimicrobial activities of curcumin (5 mM) and xanthohumol (100 μM) extracts, and the respective controls, were evaluated with 72-h biofilms formed over dental implants by their submersion for 60 seconds. The evaluation was assessed by quantitative polymerase chain reaction (qPCR), confocal laser scanning microscopy (CLSM) and scanning electron microscopy (SEM). For the data analysis, comparisons were tested applying ANOVA tests with post-hoc Bonferroni corrections to evaluate the antimicrobial activity of both extracts. With qPCR, statistically significant reductions in bacterial counts were observed for curcumin and xanthohumol, when compared to the negative control. The results with CLSM and SEM were consistent with those reported with qPCR. It was concluded that both curcumin and xanthohumol have demonstrated antimicrobial activity against the six bacterial species included in the dynamic in vitro biofilm model used.
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    Proyectos de innovación educativa aplicados al campus virtual: el Campus Virtual y la asignatura Periodoncia
    (III jornada Campus Virtual UCM : Innovación en el Campus Virtual metodologías y herramientas, 2007) Herrera González, David; Legido Arce, Berta; Cruz Astorqui, Isabel Santa; Alonso Álvarez, Bettina María; Arriba de la Fuente, Lorenzo de; Sanz Alonso, Mariano; Fernández-Valmayor Crespo, Alfredo; Fernández-Pampillón Cesteros, Ana María; Merino Granizo, Jorge
    La enseñanza basada en los problemas (PBL) supone un avance que permite a los alumnos integrar mejor los conocimientos adquiridos. La asignatura de 4.º curso de Odontología, Periodoncia, ha sido impartida de esta manera desde el curso 1999-2000. El uso de la herramienta Web-CT en combinación con el enfoque PBL ha permitido soslayar algunos de los problemas encontrados en la aplicación del PBL y mejorar el acceso a la información de todos los estamentos involucrados. Para el curso 2004-2005 se establecieron una serie de objetivos, cuyo cumplimiento es evaluado en la siguiente comunicación: 1. Uso del sistema de aprendizaje basado en los problemas. 2. Inclusión de la asignatura dentro del Campus Virtual (Web-CT). • Tutorías on-line y el contacto continuo entre estudiantes y tutores. • Búsqueda asistida de información relevante. • Colaboración en los procesos de selección de las fuentes de información. • Disponibilidad completa de todas las informaciones seleccionadas. • Disponibilidad de todos los trabajos desarrollados. • Disponibilidad de toda la información sobre el desarrollo del curso. • Disponibilidad de toda la información sobre evaluación continua. 3. Como resultado de ambos procesos, los alumnos generaron una serie de materiales que estuvieron disponibles para todos los implicados en el curso y para cursos futuros. 4. Evaluación de los resultados de este tipo de enseñanza y herramientas, con cuestionarios sobre la idoneidad del sistema, en comparación con otras asignaturas tradicionales, mediante cuestionarios anónimos disponibles en la Web.
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    Project number: 49
    Entrenamiento basado en un entorno interactivo para mejorar las competencias al final del grado. Proyecto de Innovación y Mejora de la Calidad Docente 2014. Nº de proyecto: 49
    (2014) Alonso Álvarez, Bettina María; Herrera Gonzalez, David; Sanz Alonso, Mariano; Iniesta Albentosa, Margarita; de Arriba de la Fuente, Lorenzo; Legido Arce, Berta; SantaCruz Astorqui, Isabel; Sánchez Pérez, Nerea; Mínguez Arnau, María
    Memoria final del proyecto de innovación 49
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    Project number: 176
    Desarrollo y Evaluación de un nuevo modelo de enseñanza bilingüe en Periodoncia.
    (2016) Herrera González, David; Alonso Álvarez, Bettina María; Sanz Alonso, Mariano; Iniesta Albentosa, Margarita Isabel; Arriba de la Fuente, Lorenzo; Santa Cruz Astorqui, María Isabel; Legido Arce, Berta; Figuero Ruiz, Elena
    Entorno interactivo en inglés,para permitir al alumno valorar de manera objetiva e integrada su aprendizaje en la asignatura de Periodoncia, de forma totalmente interactiva.Se realizará una evaluación de este medio virtual de aprendizaje y enseñanza.
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    Project number: 271
    Aprender educando: Experiencia ApS de promoción de la salud oral. II. De la teoría a la práctica
    (2020) Iniesta Albentosa, Margarita Isabel; Alonso Álvarez, Bettina María; Figuero Ruiz, Elena; Herrera González, David; Sanz Alonso, Mariano; Matesanz Pérez, Paula; Carrillo de Albornoz Sainz, Ana; Sanz Sánchez, Ignacio; Jiménez de la Hoz, María del Carmen; Figueiras López, Iria; Mora García, Giorgina; Otero Pregigueiro, Andrea; Robaina Tadeo, María Teresa; Romero Triviño, Beatriz
    Este proyecto tenía como objetivo desarrollar una guía para proyectos de Aprendizaje Servicio (ApS) en Odontología, que siguiera una metodología estructurada, para asegurar la calidad de este tipo de programas. Para ello, se estableció en un principio desarrollar cinco capítulos que hicieran referencia específicamente a cada una de las etapas en las que se organiza un proyecto de ApS, es decir, investigación, planificación y preparación, acción, reflexión y evaluación, y celebración. El producto final ha consistido en una obra de dos partes, donde la primera sección describe detalladamente las fases básicas de un proyecto de ApS, acompañadas por hojas de trabajo para guiar la metodología. La segunda parte narra la experiencia práctica que se ha llevado a cabo en la Facultad de Odontología de la UCM.
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    Project number: 167
    Aprender educando: Experiencia ApS de promoción de la salud oral
    (2018) Iniesta Albentosa, Margarita Isabel; Alonso Álvarez, Bettina María; Arias Paniagua, Ana María; Hidalgo Arroquia, Juan José; Figuero Ruiz, Elena; Herrera González, David; Sanz Alonso, Mariano; De la Macorra Gracía, José Carlos; Méndez González, Raquel; Figueiras López, Iria; De Oliveira Pegado Figueiredo, Frederico Eduardo
    El programa de aprendizaje-servicio realizado ha permitido que el estudiante construya su propio aprendizaje y, por lo tanto, el aprendizaje académico ha mejorado el servicio ofrecido. Hemos preparado a los estudiantes para que sepan participar de forma activa en la sociedad; y hemos generado en ellos una serie de valores que dentro del aula son más difíciles de conseguir, como empatía, responsabilidad social, liderazgo, etc.
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    Dental Biofilm Removal and Bacterial Contamination of a New Doubled-Side Thermoplastic Polyurethane-Based Toothbrush: A Crossover Study in Healthy Volunteers
    (Antibiotics, 2022) Zúñiga Uhalde, Ignacio; Iniesta Albentosa, Margarita Isabel; Virto Ruiz, Leire; Ribeiro Vida, Honorato José; Alonso Español, Andrea; Hernández Ruiz de Azcárate, Fernando; Cardona Álvarez, John Jairo; Maher Lavandero, Anushiravan; Alonso Álvarez, Bettina María; Sanz Alonso, Mariano; Herrera González, David
    Multiple toothbrush designs have been developed to enhance dental biofilm removal and decrease bacterial contamination and retention over time. Therefore, the aim of this clinical study was to compare the efficacy of a prototype of a new double-sided thermoplastic polyurethane-based toothbrush with that of a conventional nylon-bristle toothbrush. A crossover study was conducted in systemically healthy volunteers (n = 24) for two one-week periods plus one washout week. As outcome variables, plaque and gingival indices, total bacterial contamination of the toothbrushes by quantitative polymerase chain reaction (qPCR), and patient-reported outcomes were measured. Clinical and microbiological variables were analysed using a general linear model and Friedman and Wilcoxon signed-rank tests. No statistically significant differences between toothbrushes were detected neither for full-mouth PlI (p > 0.05) nor for GI (p > 0.05). Similarly, no statistically significant differences were detected for bacterial contamination after 40 seconds or 1 week of use, with results expressed either in CFU/mL or in CFU/mm2 (p > 0.05). In conclusion, the tested prototype toothbrush was as effective and safe as the control toothbrush, and the participating subjects did not experience any adverse effects from its use and rated its efficiency and effectiveness in cleaning their teeth as satisfactory.