Person: Murillo González, Jorge Alfonso
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First Name
Jorge Alfonso
Last Name
Murillo González
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Medicina
Department
Anatomía y Embriología
Area
Anatomía y Embriología Humana
Identifiers
65 results
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Now showing 1 - 10 of 65
Item Functional hypothesis of the juxtaoral organ: Role of collagen types I and III(Oral Diseases, 2021) Mérida‐García, Antonio José; Murillo González, Jorge Alfonso; Martínez Sanz, Elena; Catón Vázquez, Javier; Arráez‐Aybar, Luis A.; Martín‐Cruces, José; Cobo, Teresa; Vega, José Antonio; Mérida Velasco, José RamónItem Patterns of the circumflex femoral arteries revisited(Clinical Anatomy, 2006) Vázquez Osorio, María Teresa; Murillo González, Jorge Alfonso; Maranillo Alcaide, Eva; Parkin, Ian; Sañudo Tejero, José RamónKnowledge of variations of the circumflex femoral arteries is important when undertaking clinical procedures within the femoral region and in hip joint replacement. Since the 19th century, many different patterns have been proposed to classify their origins. This work studied a statistically reliable sample, the lower limbs of 221 embalmed human cadavers (equal right–left and approximately equal sex distributions), and reviewed the previous literature to propose a unified and simple classification that will be useful to clinicians. Statistical comparisons were made using the chi(2) test. The medial and lateral circumflex femoral arteries have been classified into three different patterns based on the levels of their origin. Distribution related to sex and side was also studied. Pattern I: Both arteries arose from the deep femoral artery (346 cases, 78.8%). This pattern was more frequent in females, P = 0.01. There was no significant difference between sides. Type Ia, medial circumflex femoral artery origin was proximal to the lateral circumflex femoral artery origin (53.2%); Type Ib, lateral circumflex femoral artery origin was proximal to medial circumflex femoral artery origin (23.4%); Type Ic, both arteries arose from a common trunk (23.4%). Pattern II: One of the arteries arose from the femoral artery and the other from the deep femoral artery (90 cases, 20.5%). Type IIa, the medial circumflex femoral artery arose from the femoral artery (77.8%) and Type IIb, the lateral circumflex femoral artery arose from the femoral artery (22.2%). There were no significant differences between sexes or sides. Pattern III: Both arteries arose from the femoral artery (2 cases, 0.5%). In every disposition there was a significantly higher prevalence of unilateral rather than bilateral occurrence. In one dissection the medial circumflex femoral artery was absent. Awareness of these variations could avoid unexpected injuries.Item A case of brachymetacarpia in a skeleton from a Mudejar cemetery from Spain (13th–14th century AD)(International Journal of Osteoarchaeology, 2021) Dorado Fernández, Enrique; Herrerín, Jesús; Ramírez, Ildefonso; Parro, Loreto; Carrillo, Manuel F.; Murillo González, Jorge AlfonsoBrachymetacarpia, a form of brachydactyly, is one of the so‐called rare diseases because of its low prevalence. Although it is a well‐known malformation today, which occasionally requires surgical correction, it is not, or hardly, reported in the palaeopathological literature. The case presented here includes an individual exhumed from the Mudejar cemetery in Uceda (Guadalajara, Spain) dated between the 13th and 14th centuries. It was in an acceptable state of preservation, except for the skull, missing except for the mandible. Its sex was determined as female and the age as a young adult. On examining the hands, the short length of both the 4th and 5th metacarpals and the shortening of the distal phalanx of one of the thumbs were noteworthy. No anomaly was observed in the bones of the feet, which were only partially recovered. Due to the characteristics of the shortening and bones affected, it was considered that the case probably corresponded to type E of brachydactyly in the Bell and Temtamy classifications and to subtype E2 in the Hertzog classification. No data were found in the bones or teeth, suggesting their inclusion in any of the multiple clinical syndromes with this abnormality.Item Arthroscopic study of the knee joint in fetuses(Arthroscopy: The Journal of Arthroscopy and Related Surgery, 2003) Tena Arregui, José; Barrio Asensio, María Del Carmen; Viejo Tirado, Fermín; Puerta Fonolla, Antonio Javier; Murillo González, Jorge AlfonsoPurpose: The purpose of this study was to macroscopically examine the fetal knee joint via arthroscopy. We have attempted to identify and describe the specific characteristics of the fetal knee joint, how it evolves during the last few weeks of intrauterine development, and any possible variations with regard to the adult knee. Type of study: Observational anatomic case series. Methods: We used 20 frozen fetuses with a gestational age of 24 to 40 +/- 2 weeks, obtained from spontaneous abortions. Examination was performed with standard arthroscopic surgical equipment, using a 2.7-mm optical lens. Whenever possible, we tried to use standard arthroscopic portals. Images were obtained for comparison with the adult knee. Results: Suprapatellar and infrapatellar septa were an almost consistent finding. The suprapatellar septum always opened laterally and was intact in the developmentally younger specimens. We found 2 mediopatellar septa. The femoral attachment of the anterior cruciate ligament (ACL) differed in appearance from that of the adult in that it was more ribbon-like. The lateral meniscus had a more spread-out appearance than its adult counterpart, especially in the specimens of a younger gestational age. We were surprised at the easy accessibility of the popliteal hiatus and the clear arthroscopic vision we were able to obtain of the involved structures. Conclusions: To our knowledge, this is the first arthroscopic study to target the fetal knee. The results indicate minimal differences when compared with the adult knee, and for some structures, such as the popliteal hiatus, the anatomy seen was easier to discern than in adult knee arthroscopy.Item Arthroscopic Study of the Shoulder Joint in Fetuses(Arthroscopy: The Journal of Arthroscopic & Related Surgery, 2005) Tena Arregui, José; Barrio Asensio, María Del Carmen; Puerta Fonolla, Antonio Javier; Murillo González, Jorge AlfonsoPurpose: The purpose of this study was to macroscopically examine the fetal shoulder joint using arthroscopy. We attempted to identify and describe the specific characteristics of the fetal shoulder joint, how it evolves during the last few weeks of intrauterine development, and any possible variations with regard to the adult shoulder. Type of Study: Observational anatomic case series. Methods: We used 20 frozen fetuses with a gestational age of 24 to 40 +/- 2 weeks, obtained from spontaneous abortions. Examination was performed with standard arthroscopic surgical equipment, using a 2.7-mm optical lens. Whenever possible, we tried to use the standard arthroscopic portals. Images were obtained for comparison with the adult shoulder. Results: The arthroscopic images of the fetal glenohumeral joint are similar to those of an adult shoulder, with the only differences being those related to the stage of development. In this study we observed no so-called bare spot in the glenoid cavity such as has been described in treatises on the adult shoulder joint. The arthroscopic images of the anterosuperior region of the fetal joint show more highly defined structures than in the adult shoulder, especially the coracohumeral and glenohumeral ligaments. Conclusions: To our knowledge, this is the first arthroscopic study to target the fetal shoulder joint. The results indicate minimal differences when compared with the adult shoulder joint; for some structures, particularly in the anterosuperior region, the anatomy observed was easier to discern than what is observed in adult shoulder arthroscopy. Clinical Relevance: Our study obtained clear images of virgin shoulder joints that had never been subjected to deterioration from wear or other distorting forces. The clarity of these images is useful for locating and identifying structures in the adult shoulder.Item Los sesamoideos de la articulación metatarsofalángica del primer dedo: una revisión sistemática(Revista Internacional de Ciencias Podológicas, 2016) Barroso Gómez, Paúl; Herrera Lara, Manuel Eugenio; Murillo González, Jorge Alfonso; Becerro De Bengoa Vallejo, RicardoLos huesos sesamoideos del primer metatarsiano no son tenidos siempre en consideración a la hora de realizar un diagnóstico, en las patologías que afectan a la región de la cabeza del primer metatarsiano. Ello es debido al escaso conocimiento de todas las entidades patológicas que pueden afectar a los sesamoideos y por la relativa poca incidencia que hasta el momento tienen. Con el aumento de las actividades de práctica deportiva, en concreto del running, cada vez se observan más afectaciones de índole clínica en esta región, relacionadas con este hueso. Métodos: Se realiza una búsqueda bibliográfica en 5 bases de datos (Medline, PubMed, Scopus, Cochrane Library y BUCEA). Los términos empleados en la búsqueda fueron: sesamoids, anatomy, biomechanics, sesamoids review y sesamoids pathology. En la búsqueda inicial se tienen en cuenta los artículos con menos de 10 años, ceñidos a humanos y textos de revisión. Resultados: Se seleccionan 24 artículos que incluyen diferentes patologías con sus consiguientes diagnósticos mediante pruebas de imagen y tratamientos, tanto conservadores como quirúrgicos; así como aspectos de la biomecánica de la articulación metatarso-sesamoidea. Conclusión: Los sesamoideos debido a su anatomía, topografía y función pueden estar involucrados en un gran número de patologías; con signos y síntomas generalmente similares entre ellas y que pueden llevar al podólogo clínico a la confusión a la hora de realizar un diagnóstico y un tratamiento acertados.- Project number: 165
Item Desarrollo de un sistema interactivo para el estudio de la órbita y su contenido: anatomía macroscópica(2023) Asensio, Carmen; Arráez Aybar, Luis Alfonso; Catón Vázquez, Francisco Javier; García Serradilla, Moisés; Garcia Gómez, Susana; García de Pereda Notario, Carlos Miguel; Maldonado Bautista, Estela; Martínez Sanz, Elena; Mérida Velasco, José Ramón; Murillo Barrio, Jaime; Murillo González, Jorge Alfonso; Naredo Sánchez, Esperanza; Paradas Lara, Irene; Virto Ruiz, LeireEn este proyecto se ha desarrollado un sistema interactivo para mejorar el proceso de enseñanza-aprendizaje en la docencia de la anatomía macroscópica de la órbita y su contenido por medio de preparaciones anatómicas. Se pretende facilitar el aprendizaje de forma autónoma en español e inglés y, la autoevaluación sobre los conocimientos adquiridos. Item Connections between the internal and the external capsules and the globus pallidus in the sheep: A dichromate stain X‐ray microtomographic study(Anatomia Histologia Embryologia, 2020) Murillo González, Jorge Alfonso; Notario, Belen; Maldonado Bautista, Estela; Martínez Sanz, Elena; Barrio Asensio, María Del Carmen; Herrera Lara, Manuel EugenioSheep are recognized as useful species for translational neurodegeneration research, in particular for the study of Huntington disease. There is a lack of information regarding the detailed anatomy and connections of the basal ganglia of sheep, in normal myeloarchitectonics and in tract-tracing studies. In this work, the organization of the corticostriatal projections at the level of the putamen and globus pallidus (GP) are explored. For the first time, the myeloarchitectonic pattern of connections between the internal (IC) and the external (EC) capsules with the GP have been investigated in the sheep. Formaldehyde-fixed blocks of the striatum were treated with a metallic stain containing potassium dichromate and visualized using micro-CT (µ-CT). The trivalent chromium (Cr3+), attached to myelin phospholipids, imparts a differential contrast to the grey and white matter compartments, which allows the visualization of myelinated fascicles in µ-CT images. The fascicles were classified according to their topographical location in dorsal supreme fascicles (X, Y, apex) arising from the IC and EC; pre-commissurally, basal fascicles connecting the ventral part of the EC with the lateral zone of the ventral pallidum (VP) and, post-commissurally, superior (Z1 ), middle (Z2 ) and lower (Z3 ) fascicles, connecting at different levels the EC with the GP. The results suggest that the presumptive cortical efferent and afferent fibres to the pallidum could be organized according to a dorsal to ventrolateral topography in the sheep, similar to that seen in other mammals. The proposed methodology has the potential to delineate the myeloarchitectonic patterns of nervous systems and tracts.Item Development of the long head of the biceps brachial tendon: A possible explanation of the anatomical variations(Annals of Anatomy, 2018) Minuesa-Asensio, Alvaro; Murillo González, Jorge Alfonso; Cuadra Blanco, Crótida De La; Arráez Aybar, Luis Alfonso; Herrera Lara, Manuel Eugenio; Mérida Velasco, José RamónThe anatomical variations of the proximal portion of the long head of the biceps brachii tendon (LHBT) are rarely observed in clinical practice. However, an increase in the rate of shoulder arthroscopic surgery has led to an increase in the observation of anatomical variations of this region. The aim of this work was to analyze the development of the LHBT in 23 human embryos ranging from the 6th to 8th weeks of development. The LHBT develops from the glenohumeral interzonal mesenchyme in the 6th week. By week 7, the myotendinous junction of the LHBT develops. The anlage of the LHBT is separated from that of the glenohumeral capsule during week 8. Our results suggest that the most important period for the LHBT development occurs between the 6th and 8th weeks of embryonic development. Alterations during this critical period may cause anatomical variations of the LHBT. An additional case report from our own experience is provided as Supplementary material.Item Anatomic relationship of the proximal nail matrix to the extensor hallucis longus tendon insertion(European Academy of Dermatology and Venereology, 2015) Palomo López, P.; López López, D.; M.E. Losa Iglesias; Becerro De Bengoa Vallejo, Ricardo; Prados Frutos, Juan Carlos; Murillo González, Jorge AlfonsoBackground: The purpose of this study was to delineate the relationship of the terminal extensor hallucis longus tendon insertion to the proximal limit of the nail matrix of the great toe. Material and methods: Fifty fresh-frozen human cadaver great toes with no evidence of trauma (average age, 62.5 years; 29 males and 21 females) were used for this study. Under 25X magnification, the proximal limit of the nail matrix and the terminal bony insertion of the extensor hallucis longus tendons were identified. The distance from the terminal tendon insertion to the nail matrix was ascertained using precision calipers, an optical microscope, and autocad(®) software for windows. Twenty-five great toes were placed in a neutral formalin solution and further analysed by histological longitudinal-sections. The specimens were stained with haematoxylin and eosin and examined microscopically to determine the presence of the extensor hallucis longus tendon along the dorsal aspect of the distal phalanx of each great toe. Results: The main result we found in great toes was that the extensor tendon is between the matrix and the phalanx and extends dorsally to the distal aspect of the distal phalanx in all, 100%, specimens. The nail matrix of the great toe is not attached to the periosteum of the dorsal aspect of the base of the distal phalanx as is the case for fingers, because the extensor hallucis tendon is plantar or directly underneath the nail matrix and the tendon is dorsal to the bone. Conclusions: We have found that the extensor tendon is between the matrix and the phalanx and extends dorsally to the distal aspect of the distal phalanx. The nail matrix of the great toe is not attached to the periosteum of the dorsal aspect of the base of distal phalanx as is the case in fingers, because the extensor hallucis tendon is plantar or directly underneath the nail matrix and the tendon is dorsal to the bone. Our anatomic study demonstrates that the proximal limit of the matrix and nail bed of the human great toe are dorsal and overlapping the terminal extensor hallucis longus tendon until its distal bony insertion in all specimens.