Person: Canfrán Arrabe, Susana
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First Name
Susana
Last Name
Canfrán Arrabe
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Veterinaria
Department
Medicina y Cirugía Animal
Area
Medicina y Cirugía Animal
Identifiers
12 results
Search Results
Now showing 1 - 10 of 12
- Project number: 297
Item Gamificación en anestesiología clínica veterinaria(2019) Canfrán Arrabe, Susana; Álvarez Gómez De Segura, Ignacio; Cediel Algovia, Rafael; Aguado Domínguez, Delia; Bustamante Domínguez, Rocío; García Sanz, Virginia; García Gómez, Andrea; Grijota Chousa, Óscar José; Morcuende Rodríguez, ÁfricaEn el presente proyecto se propuso el desarrollo de un juego de mesa que permitiese el aprendizaje de conceptos teóricos relacionados con la anestesia en un entorno de gamificación. La gamificación se define como el empleo de mecánicas de juego en entornos y aplicaciones no lúdicas con el fin de potenciar la motivación, la concentración y el esfuerzo. Con ello se pretendía complementar la docencia teórica de la asignatura de Cirugía General y Anestesia de cuarto curso de Grado en Veterinaria. Este recurso y la metodología planteada han pretendido facilitar y mejorar el aprendizaje de diversos conceptos de anestesiología clínica en el ámbito de la docencia del Grado en Veterinaria. Con ello, se pretendía mejorar la adquisición de una serie de competencias necesarias para los graduados en Veterinaria, de cara a poder desempeñar adecuadamente su actividad práctica clínica. - Project number: 211
Item Implementación del uso de códigos QR como apoyo a la docencia clínica de la anestesiología veterinaria.(2016) Canfrán Arrabe, Susana; Aguado Domínguez, Delia; Cediel Algovia, Rafael; Álvarez Gómez De Segura, Ignacio; Re, Michela TatianaLos Graduados en Veterinaria deben haber adquirido a lo largo de su formación una serie de competencias, entre las que cobran especial importancia todas aquellas relacionadas con la práctica clínica. Con el presente proyecto se pretende generar recursos de formación educativos en el ámbito de la docencia del Grado en Veterinaria, facilitando, en concreto, el aprendizaje de la anestesiología práctica. Una forma eficaz de apoyo al aprendizaje es el empleo de medios audiovisuales en los que el alumno pueda observar vídeos, imágenes o esquemas de la técnica a realizar para posteriormente desarrollarla él mismo. En un contexto hospitalario sería muy deseable la posibilidad de acceso directo del alumno a este tipo de material audiovisual de soporte in situ y de forma directa mediante dispositivos electrónicos de uso común (por ejemplo, teléfonos móviles), de forma que tenga acceso al contenido que necesite repasar en cada momento. Para lograr este objetivo, este proyecto propone la incorporación de códigos QR al área hospitalaria de Anestesiología del HCVC. El empleo de códigos QR en el entorno hospitalario permitiría al alumno enlazar de forma rápida a contenidos seleccionados específicamente para apoyar diferentes aspectos de la docencia práctica. Los materiales codificados mediante sistema QR son complementarios a otros métodos docentes, pero la ampliación del conocimiento que puede derivarse de ellos redundará en una mejor comprensión de los conceptos tratados y en un aumento significativo del aprendizaje. Item Ultrasound-guided modified subcostal transversus abdominis plane block in a foal undergoing omphalectomy(Equine Veterinary Education, 2023) López Ramis, Víctor; Santiago Llorente, Isabel; Manso Díaz, Gabriel; Canfrán Arrabe, Susana; Álvarez Gómez De Segura, IgnacioA 7-day-old, 60 kg, Purebred Spanish Horse filly was referred with the mare to Complutense University of Madrid, Veterinary teaching hospital for elective omphalectomy. Upon admission, clinical examination was unremarkable except for a thickening of the umbilical area. Haematology and biochemistry values were within the normal range. On abdominal ultrasound (US) examination, a well-defined, rounded (24 mm of diameter) area that contained heterogeneous material with numerous hyperechoic foci with acoustic shadowing was seen within the inner portion of the umbilical pedicle, between both umbilical arteries. Surgical correction with omphalectomy was scheduled. To provide perioperative analgesia, the transversus abdominis plane (TAP) block was considered. Under general anaesthesia, TAP block was performed in both left and right hemi-abdominal walls with a modified subcostal approach with two-site injections. A spinal needle was inserted under US guidance. During surgery, end-tidal concentration of isoflurane was maintained at 0.7%–0.9%. Surgery was completed uneventfully and no signs of nociceptive input were observed, suggesting an adequate level of analgesia. Therefore, this TAP block technique may be considered to provide analgesia for surgical procedures involving the abdominal wall in foals.Item Intraoperative effect of low doses of ketamine or dexmedetomidine continuous rate infusions in healthy dogs receiving propofol total intravenous anaesthesia and epidural anaesthesia: A prospective, randomised clinical study(Research in Veterinary Science, 2022) Bustamante Domínguez, Rocío; Canfrán Arrabe, Susana; Álvarez Gómez De Segura, Ignacio; Aguado Domínguez, DeliaThe present study aimed to determine the effect of either ketamine or dexmedetomidine constant rate infusion (CRI) on intraoperative propofol anaesthetic requirements during total intravenous anaesthesia (TIVA) in healthy dogs undergoing hindlimbs orthopaedic procedures receiving epidural anaesthesia. In this randomised, blinded clinical study, thirty-nine healthy client-owned dogs were premedicated intramuscularly (dexmedetomidine 4 μg/kg and methadone 0.3 mg/kg). General anaesthesia was induced to effect with propofol administered as intravenous bolus, and maintained with propofol TIVA (18 mg/kg/h), adjusted to meet the suitable clinical anaesthetic depth (indicatively±20%) based on clinical judgement. Lumbosacral epidural anaesthesia was performed using bupivacaine (1 mg/kg) and morphine preservative free (0.1 mg/kg). Dogs randomly received either saline (SP; loading dose 1 mL/kg, CRI 1 mL/kg/h), or ketamine (KP; loading dose 1.5 mg/kg, CRI 1.5 mg/kg/h), or dexmedetomidine (DP; loading dose 1 μg/kg/, CRI 1 μg/kg/h). Physiological variables were recorded intraoperatively at 5-min intervals using standard-of-care monitoring. Recovery quality and duration were recorded. Treatment groups were compared with parametric and non-parametric tests as appropriate, p < 0.05. Propofol rates and recovery scores were similar between groups. Overall mean and diastolic blood pressures were higher in group DP compared to group KP (12–14 mmHg, p = 0.016 and p = 0.015, respectively). More dogs required mechanical ventilation in group KP (12 dogs) than in either group SP or DP (7 dogs per group, p = 0.037). Ketamine or dexmedetomidine CRIs, at the studied rates, did not reduce propofol TIVA requirements in dogs undergoing orthopaedic surgery with epidural anaesthesia.- Project number: 162
Item Desarrollo de vídeos doodle como apoyo a la docencia en anestesiología veterinaria(2018) Aguado Domínguez, Delia; Álvarez Gómez De Segura, Ignacio; Cediel Algovia, Rafael; Canfrán Arrabe, Susana; Bustamante Domínguez, Rocío; García Sanz, Virginia; Romana Muñoz, Sara - Project number: 172
Item Gamificación en Anestesiología Clínica Veterinaria: Ampliación(2020) Aguado Domínguez, Delia; Álvarez Gómez De Segura, Ignacio; Cediel Algovia, Rafael; Bustamante Domínguez, Rocío; Canfrán Arrabe, Susana; Arenillas Baquero, Mario; López Ramis, Víctor; García Sanz, Virginia; Grijota Chousa, Óscar José; Gámez Maidanskaia, Ekaterina; Romero Marco, Patricia; García Gómez, Andrea; González Lendínez, AndreaDesarrollo de un juego de mesa que permitan el aprendizaje de conceptos teóricos relacionados con la anestesia en un entorno de gamificación. Item Clinical comparison of the effects of isoflurane or propofol anaesthesia on mean arterial blood pressure and ventilation in dogs undergoing orthopaedic surgery receiving epidural anaesthesia(Veterinary Journal, 2018) Canfrán Arrabe, Susana; Álvarez Gómez De Segura, Ignacio; Cediel Algovia, Rafael; Bustamante Domínguez, Rocío; Aguado Domínguez, DeliaThe aim of this study was to compare the effects on mean arterial pressure (MAP) and ventilation of propofol total IV anaesthesia (TIVA) and isoflurane as anaesthetic maintenance in healthy dogs undergoing orthopaedic surgery, with epidural anaesthesia. Dogs were premedicated IM with dexmedetomidine (4 μg/kg) and methadone (0.3 mg/kg), induced with IV propofol (0.65–5 mg/kg) and randomly assigned to be maintained with isoflurane (group I) or propofol (group P). Isoflurane end-tidal concentration (EtISO) and propofol infusion rate were adjusted during the surgery to maintain a suitable anaesthetic depth. All dogs received bupivacaine (1 mg/kg) and morphine (0.1 mg/kg) in the lumbosacral epidural space (total volume 0.2 mL/kg). MAP was recorded every 5 min during the procedure. Statistical analysis was performed using parametric (Student's t test) and nonparametric (Mann–Whitney U-test, chi-square) tests, as appropriate. Anaesthetic maintenance in groups I and P was accomplished by providing a mean EtISO of 1.12 ± 0.15% and a mean propofol infusion rate of 15.0 ± 4.7 mg/kg/h, respectively. MAP was significantly higher in group P than in group I (92 ± 17 mmHg versus 78 ± 10 mmHg; P = 0.021). Eleven dogs in group P and two dogs in group I reached an EtCO2 > 7.3 kPa, requiring mechanical ventilation (P = 0.001). In combination with epidural anaesthesia, propofol TIVA improved MAP and is a suitable alternative to isoflurane in orthopaedic surgery of the hind limb in healthy dogs. Nevertheless, since it was associated with increased respiratory depression, mechanical ventilation should be available.Item Efectos pulmonares y hemodinámicos del reclutamiento alveolar progresivo durante la anestesia en el perro(2013) Canfrán Arrabe, Susana; Álvarez Gómez de Segura, Ignacio; Cediel Algovia, Rafael; García Fernández, JavierLas maniobras de reclutamiento se pueden utilizar para tratar las atelectasias que se producen durante la anestesia general, mejorando por tanto la mecánica pulmonar y el intercambio gaseoso. Sin embargo, estas maniobras presentan algunos riesgos, que incluyen la posibilidad de producir barotrauma y el deterioro hemodinámico. Estas maniobras no han sido estudiadas en profundidad en el paciente canino. Objetivos Este estudio se dividió en tres sub-estudios para desarrollar tres objetivos diferentes. Primero, empleando pulmones sanos de conejo, el objetivo fue determinar el rango de presiones que pueden utilizarse con seguridad para lograr la apertura pulmonar total sin causar barotrauma (estudio 1). El segundo estudio se realizó para evaluar los efectos de una maniobra de reclutamiento progresiva sobre el gasto cardiaco en perros sanos, utilizando o no un bolo previo de fluidos (estudio 2). El objetivo del tercer trabajo fue evaluar los efectos de una maniobra progresiva sobre la distensibilidad dinámica pulmonar y el intercambio gaseoso en pacientes clínicos caninos (estudio 3). Materiales y Métodos Estudio 1 Se realizó un estudio experimental, prospectivo, aleatorio, empleando 14 conejos sanos de 12 semanas de edad. Los animales fueron eutanasiados, y se abrió la cavidad torácica y ambos espacios pleurales. Se asignó aleatoriamente cada animal a uno de dos grupos y se realizó una maniobra de reclutamiento, descrita a continuación. La presión positiva final espiratoria (PEEP) se fue incrementando de 5 en 5 cmH2O desde 0 cmH2O hasta 20 cmH2O (grupo PEEP-20) o 50 cmH2O (grupo PEEP-50). El diferencial de Resumen 136 presión entre la PEEP y la presión inspiratoria máxima se mantuvo en 15 cmH2O en ambos grupos. Una vez que la PEEP máxima de grupo fue alcanzada, el diferencial de presión se fue aumentando de 5 en 5 cmH2O hasta que se observó barotrauma directo. Se definieron tres condiciones pulmonares macroscópicas: apertura pulmonar anatómica, umbral de sobredistensión y barotrauma. En cada una de ellas, se midió la presión inspiratoria máxima, PEEP y presión diferencial. Se determinó también un margen de seguridad, definido como la diferencia entre la presión inspiratoria máxima que produjo barotrauma y aquella que consiguió la apertura pulmonar. El test de la t de Student se utilizó para comparar los resultados obtenidos en ambos grupos... ABSTRACT. Recruitment manoeuvres can be used to reverse atelectasis during general anaesthesia, thus improving lung mechanics and gas exchange. Nevertheless, they present some risks, as the development of barotrauma and the haemodynamic impairment. These manoeuvres have not been studied in detail in canine patients. Objectives This study was divided in three sub-studies to achieve different objectives: first, using healthy rabbit lungs, the aim was to explore the range of pressures that can be safely used to fully recruit the lung without causing barotrauma (Study 1). Second study was performed to evaluate the effects of a stepwise recruitment manoeuvre on cardiac output (CO) in mechanically ventilated healthy dogs, with or without a previous fluid load (Study 2). The third study was performed to evaluate the effects of a stepwise lung recruitment manoeuvre on dynamic lung compliance and gas exchange in clinical canine patients (Study 3). Materials and Methods Study 1 A prospective, randomized, experimental study, using fourteen healthy young rabbits (aged 12 weeks old), was performed. Animals were euthanized, the thorax and both pleural spaces were opened, and they were randomized into two recruitment manoeuvre groups. Positive end-expiratory pressure (PEEP) was incrementally increased by 5 cmH2O from 0 cmH2O to 20 cmH2O (PEEP-20 group) or 50 cmH2O (PEEP-50 group). A driving pressure of 15 cmH2O was maintained in both groups. Once maximal PEEPs and their corresponding maximal inspiratory pressures were reached, driving pressure was Summary 142 increased by 5 cmH2O until the macroscopic barotrauma occurred. Three macroscopic conditions were defined: anatomic open lung, overdistension threshold and barotrauma. Maximal inspiratory pressure, PEEP and driving pressure were measured in the three lung conditions. A pressure safety range (defined as the difference between barotrauma maximal inspiratory pressure and anatomic open lung maximal inspiratory pressure) was determined in both groups...Item Clinical evaluation of the sedative, antinociceptive and cardiorespiratory effects of intranasal dexmedetomidine combined with methadone in healthy dogs(The Veterinary Journal, 2024) Bustamante Domínguez, Rocío; Gómez de Segura IA; Canfrán Arrabe, SusanaIn this prospective, randomised, blinded clinical study, we compared the sedative, antinociceptive and cardiorespiratory effects of intranasal (IN) dexmedetomidine at 5 μg/kg (diluted with 0.03 mL/kg NaCl 0.9%, DEX) with or without methadone (0.3 mg/kg; DEXMET), through a mucosal atomization device to one nostril in twenty healthy client-owned dogs. At 5-min intervals over 45 min, sedation score, onset, cardiopulmonary variables, mechanical nociceptive thresholds (MNTs) were assessed, also ease of administration, adverse effects, and response to IV catheterization. Statistical analysis employed t-test, the Mann-Whitney U, repeated measures ANOVA and Chi-square tests as appropriate (P < 0.05). Higher sedation ocurred in DEXMET (7 [5–10]) compared to DEX (5 [2–7]) from 15 to 30 min (P < 0.01, median [interquartile range]). Heart rate was lower in DEXMET (P < 0.01; 65% reduction vs. 41% in DEX, P = 0.001). The MNTs were higher in DEXMET than DEX from 15 to 45 min (P < 0.01), peaking at T30 (17.1 ± 3.8, DEXMET and 8.5 ± 5.4 N, DEX). No differences were observed in mean arterial blood pressure and respiratory rate. Intranasal administration was considered easy for 8 dogs per group. Reverse sneezing (8 dogs; P < 0.001), sialorrhea and retching (4 and 2 dogs, respectively) occurred in DEXMET. Response to catheterisation was lower in DEXMET than DEX (P = 0.039; 2 and 7 dogs, respectively). In conclusion, intranasal methadone (0.3 mg/kg) increased the sedative and antinociceptive effects produced by dexmedetomidine (5 μg/kg) in healthy dogs and resulted in lower heart rate.Item Effect of recumbency and body condition score on open-lung positive end-expiratory pressure and respiratory system compliance following a stepwise lung recruitment manoeuvre in healthy dogs during general anaesthesia(Research in Veterinary Science, 2020) García Sanz, Virginia; Canfrán Arrabe, Susana; Álvarez Gómez De Segura, Ignacio; Aguado Domínguez, DeliaThe aim was to assess the effects of recumbency and body condition score (BCS) on open-lung positive end-expiratory pressure (OL-PEEP) and quasistatic respiratory system compliance (Crs) following stepwise lung recruitment manoeuvre (RM) in healthy dogs under general anaesthesia. Thirty-four dogs were anaesthetised and mechanically ventilated (tidal volume of 10 mL/kg) without PEEP for 1 min (baseline). A stepwise RM was then performed and the individual OL-PEEP was subsequently applied. The Crs was registered at baseline and every 10-min for 50 min after RM. Dogs were classified into either dorsal or lateral recumbency groups, and as normal (score 4–5/9) or high (≥6/9) BCS groups. The OL-PEEP was higher in lateral than in dorsal recumbency (P = .002), but differences were not observed between normal and high BCS (P = .865). The Crs was increased from baseline at all time points after RM in all groups. The Crs did not differ between dorsally and laterally recumbent dogs at any time point. However, the baseline Crs was significantly lower in dogs with a high BCS than in those with a normal BCS (P < .001); therefore, the absolute change from baseline was considered when comparing Crs after the RM and it was similar in both BCS groups. In conclusion, in anaesthetised healthy dogs the OL-PEEP following RM was lower when dogs were positioned in dorsal than in lateral recumbency. The Crs after RM remained unchanged regardless of the dogs' recumbency. A stepwise RM followed by OL-PEEP could compensate for the potential negative impact of moderately increased BCS on Crs.