Person: García Montero, María
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First Name
María
Last Name
García Montero
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Óptica y Optometría
Department
Optometría y Visión
Area
Optica
Identifiers
33 results
Search Results
Now showing 1 - 10 of 33
Item The role of clinical diagnosis criteria on the frequency of accommodative insufficiency(International journal of ophthalmology, 2019) García Montero, María; Antona Peñalba, Beatriz; Barrio de Santos, Ana Rosa; Nieto Zayas, Carmen; Martínez Alberquilla, Irene; Hernández Verdejo, José LuisAIM: To estimate and compare the frequency of accommodative insufficiency (AI) within the same clinical population sample depending on the type of clinical criteria used for diagnosis. Comparing the frequency within the same population would help to minimize bias due to sampling or methodological variability. METHODS: Retrospective study of 205 medical records of symptomatic subjects free of any organic cause and symptoms persisting despite optical compensation evaluated. Based on the most commonly clinical diagnostics criteria found in the literature, four diagnostics criteria were established for AI (I, II, III and IV) based on subjective accommodative tests: monocular accommodative amplitude two or more diopters below Hofstetter’s minimum value [15-(0.25×age)] (I, II, III, IV); failing monocular accommodative facility with minus lens, establishing the cut-off in 0 cycles per minute (cpm) (I) and in 6 cpm (II, III); failing binocular accommodative facility with minus lens, establishing the cut-off in 0 cpm (I) and in 3 cpm (II). RESULTS: The proportion of AI (95%CI) for criteria I, II, III and IV were 1.95% (0.04%-3.86%), 2.93% (0.31%-4.57%), 6.34% (1.90%-7.85%) and 41.95% (35.14%-48.76%) respectively, with a statistically significant difference shown between these values (χ2=226.7, P<0.001). A pairwise multiple comparison revealed that the proportion of AI detected for criterion IV was significantly greater than the proportion for the rest of the criteria (P-adjusted<0.05 in all cases). CONCLUSION: The prevalence of cases of AI within the same clinical population varies with the clinical diagnostic criteria selected. The variation is statistically significant when considering the monocular accommodative amplitude as the only clinical diagnostic sign.Item Randomized crossover trial of silicone hydrogel contact lenses(Contact Lens and Anterior Eye, 2018) García Montero, María; Rico del Viejo, Laura; Llorens Quintana, Clara; Lorente Velázquez, Amalia; Hernández Verdejo, José Luis; Madrid Costa, DavidPurpose: The aim of the current study is to assess, using new technologies, the interaction of four monthly silicone hydrogel contact lenses on the ocular surface and the comfort over 15 days of use. Methods: Prospective cross-over, randomized and double-masked study including four materials (lotrafilcon-B, samfilcon-A , comfilcon-A and filcom-V3). Clinical examination was performed in the following order: tear meniscus height, first break-up of the tear film, the average time of all tear film breakup incidents, bulbar redness, limbal redness (Keratograph 5M ,Oculus, Germany); central corneal thickness (Pentacam, Oculus, Germany), thermography values (FLIR A325; FLIR Systems Inc., USA), and slit-lamp evaluations, including ocular surface staining. Finally, subjective comfort was obtained from Contact Lens Dry Eye Questionnaire-8. Results: The impact of contact lens wear on the ocular surface didn’t show statistically significant changes over time except for corneal and conjunctival staining grades on day 15 compared to day 1 for the comfilcon A group (P = .003 and P = .01, respectively). Contact lens stability and impact on the ocular surface during contact lens wear didn’t show statistically significant changes over time except in the case of the comfilcon A material with respect to the irritation item (P = .01). Conclusions: These results suggest that the impact of monthly silicone hydrogel contact lens materials on the ocular surface after and during contact lens wear, contact lens stability over time, and subjective comfort did not reveal any significant changes over 15 days of use for any of the materials.Item Effects of Blink Rate on Tear Film Optical Quality Dynamics with Different Soft Contact Lenses(Journal of Ophthalmology, 2019) García Montero, María; Rico del Viejo, Laura; Martínez Alberquilla, Irene; Hernández Verdejo, José Luis; Lorente Velázquez, Amalia; Madrid Costa, DavidObjective. The aim of this study was to investigate tear film optical quality dynamics for four types of silicone hydrogel contact lenses (SHCLs) for daily wear over a 15-day period and for different blink rate (BR) patterns. Methods. A prospective randomized, double-blind, cross-over pilot study including four SHCLs (A: lotrafilcon B (Air Optix plus HydraGlyde, Alcon Laboratories); B: samfilcon A (Ultra, Bausch & Lomb); C: comfilcon A (Biofinity, CooperVision); and D: filcom V3 (Blu:gen, Mark’Ennovy)). Serial measurements of Objective Scatter Index (OSI) using the HD Analyzer (Visiometrics S.L., Terrassa, Spain) were taken at different blinking patterns: blinking every 2.5 seconds (high BRs) and every 9 seconds (low BRs). They were performed during the first visit before CL insertion (baseline), after 20 minutes of CL wear (Day 1), and during the last visit after 8 hours of CL wear on day 15 of use (Day 15). Results. Normal young healthy subjects were recruited and fitted with the four lenses. For low BRs, the mean OSI value increased over time for all CLs and the slope of the curve also increased for all CLs, except for CL D. However, for high BRs, the mean OSI value increased only for CLs B and C and the slope of the curve did not change over time for any of them. Conclusions. These results suggest that the tear film optical quality dynamics after wearing SCHLs for 15 days seems to undergo a slight deterioration only for lowest BR.Item Ocular Surface Temperature in DED under Natural Non-Controlled Blinking Conditions(Applied Sciences, 2022) Rico del Viejo, Laura; Llorens Quintana, Clara; Martínez Alberquilla, Irene; Madrid Costa, David; García Montero, MaríaInfrared (IR) thermography is a tool to non-invasively assess the tear film temperature. The aim was to analyze ocular surface temperature (OST) variations in dry eye disease (DED) and control eyes under natural non-controlled blinking conditions. Imaging was performed with a thermal camera (FLIR Systems Inc.) at 30 Hz framerate in 79 participants (39 DED (62.5% women, average age 48 ± 20 years) and 40 control (46.2 % women, average age 38 ± 13 years)) using non-contact IR thermography camera. Data acquisitions were performed in natural blinking conditions for 40 s. IR images were analyzed using a custom algorithm that calculates the OST indexes: mean OST, OST at the start and at the end, minimum and maximum OST, and tear evaporation rate (TER). No significant differences were found between groups in any thermal parameter analyzed (paired comparisons t-test, p > 0.05). In conclusion, the findings of this study did not reveal significant differences between DED and control eyes under natural non-controlled blinking conditions. However, the presence of clinical signs in the control group may affect the results, highlighting the role of DED diagnosis criteria.Item Comparison of the impact of nesofilcon A hydrogel contact lens on the ocular surface and the comfort of presbyopic and non-presbyopic wearers(International journal of ophthalmology, 2019) Lorente Velázquez, Amalia; García Montero, María; Gómez Sanz, Fernando Javier; Rico del Viejo, Laura; Hernández Verdejo, José Luis; Madrid Costa, DavidAIM: To assess and compare the impact of a daily disposable contact lens (CL) with high water content on the ocular surface and comfort of the presbyopic and non-presbyopic population after one day of use. METHODS: Totally 20 presbyopes and 30 non-presbyopes non-contact wearers were fitted with nesofilcon A CLs. CL thickness was measured to assess material stability during daily wear, and ocular surface parameters were also assessed. Optical quality was analyzed for all cases. In addition, CL comfort was rated. RESULTS: No significant differences were found in CL thickness, tear film osmolarity, average tear break-up time, bulbar redness, central corneal thickness, corneal volume, root-mean-square of higher-order aberrations (RMS of HOAs) and vertical and horizontal coma, either as a function of the group or time of use. A significant decrease in tear meniscus height and first break-up of the tear film was found in the presbyopic group (P=0.038; P=0.007 respectively). A decrease in spherical aberration coefficient was found after CL insertion (P=0.031 monofocal CL; P=0.023 low addition multifocal CL; P=0.016 high addition multifocal CL). Multifocal CL were thicker than monofocal CL (P=0.045). Comparison between groups showed more discomfort in presbyopes than non-presbyopes (P=0.003). CONCLUSION: This study evidence that the behavior of the daily disposable CL with high water content seems to be stable during the day of use. Ocular parameters measured during wear show that CL behavior is the same for presbyopes and non-presbyopes, being more uncomfortable for presbyopes.Item Repeatability of Noninvasive Keratograph 5M Measurements Associated With Contact Lens Wear(Eye & Contact lens, 2019) García Montero, María; Rico del Viejo, Laura; Lorente Velázquez, Amalia; Martínez Alberquilla, Irene; Hernández Verdejo, José Luis; Madrid Costa, DavidObjetive: To assess the intrarater repeatability of the measurements of tear meniscus height (TMH), noninvasive keratograph tear break-up time (NIKBUTs), and ocular redness measurements obtained with the Keratograph 5M (K5M) in a sample of soft silicone hydrogel contact lens (CL) wearers over 15 days. Methods: Prospective study over two consecutive weeks. Three measurements of TMH, NIKBUTs (NIKBUT first and NIKBUT average), and ocular redness were obtained in different sessions; the first day (baseline, at 8 hr of wear, and after lens removal) and the last day of wear-15th day (at 8 hr of wear and after lens removal). The repeatability of measurements were assessed by two intraclass correlation coefficient (ICC) forms; single measurement [ICC (2,1)] and multiple measurements (k=3) [ICC (2, k)]. Results: Sixty-four eyes were analyzed. The repeatability of baseline TMH [ICC (2,1) greater than 0.90; coefficient of repeatability (CR)=0.06 mm] and after and during CL wear [ICC (2,k) greater than 0.90; CR≤0.07 mm] were excellent. The repeatability of baseline NIKBUT average [ICC (2,k)=0.89 (0.82-0.93); CR=6.07 sec] was maintained after CL removal but was poorer during CL wear. The repeatability of baseline NIKBUT first [ICC (2,k) =0.80 (0.69-0.87); CR=8.74 sec] was maintained after CL removal and during CL wear at moderate-good level. Conclusions: Intrarater repeatability of TMH, NIKBUTs, and ocular redness performed by K5M after CL wear remains stable when three measurements are performed. However, intrarater repeatability during CL wear decreased only for NIKBUT average and was not affected by time of use (15 days).Item The influence of meibomian gland loss on ocular surface clinical parameters(Contact Lens and Anterior Eye, 2019) Rico del Viejo, Laura; Benítez del Castillo, José Manuel; Gómez Sanz, Fernando Javier; García Montero, María; Llorens Quintana, Clara; Madrid Costa, DavidPurpose: To assess the relationship between the meibomian gland loss (MGL) and relevant ocular surface clinical parameters as well as the influence of age in this relationship. Methods: A total of 161 participants (mean age; 42±17 years) were enrolled in this study. Infrared meibography was performed using Keratograph 5M (K5M; Oculus GmbH, Wetzlar). Participants were divided into five groups according to total meiboscore and the ocular surface parameters of each MGL group were studied. In addition, the relationship between MGL and the ocular surface parameters was established including age as covariant. Results: Both eyelids were taken into account since no association between the MGL from upper and lower eyelid was found (k value=0.2; p=0.3) despite they were significantly correlated (r= 0.3; p<0.001). No statistically significant differences were found in symptomatology among different MGL groups. Statistically significant differences were found among MGL groups in tear osmolarity (p=0.02), bulbar redness (p=0.04), corneal and conjunctival staining (p=0.01 and p=0.004, respectively). Despite this, only corneal staining showed a significant correlation with MGL when age was covariant (r=0.2; p=0.04). Conclusions: MGL higher than 50% seems to be accompanied by signs on the ocular surface. Furthermore, age demonstrated to be a relevant factor when assessing MGL. For this reason, future studies should compare age-matched groups in order to know the contribution of the MGL on the ocular surface and establish valid cut-off values for dry eye diagnosis.Item Revisiting Javal’s rule: a fresh and improved power vector approach according to age(Graefe's Archive for Clinical and Experimental Ophthalmology, 2023) Salvador Roger, Raquel; Albarran Diego, César; Garzón Jiménez, Nuria; García Montero, María; Muñoz, Gonzalo; Micó, Vicente; Estebe Taboada, José J.Purpose: The scientific community has established Javal’s rule as a model linking refractive (RA) and keratometric (KA) astigmatism since its appearance more than 100 years ago. The aim was to improve the accuracy of this relationship according to subject’s age by applying the power vector analysis. Posterior corneal curvature has also been studied. Methods: The IOLMaster 700 optical biometer was used to measure the corneal thickness and the radius of curvature of the anterior and posterior corneal surfaces. Refractive error was determined by a non-cycloplegic subjective refraction process with trial lenses. Linear regression analyses were applied using J0 and J45 power vector components. An evaluation was carried out according to the subject’s age resulting into eight regression relationships for each astigmatic vector component for each relationship. Results: A total of 2254 right eyes from 2254 healthy subjects were evaluated. A trend towards against-the-rule astigmatism (ATR) was found with aging, both for refractive astigmatism (RA) and keratometric astigmatism (KA), with 95.2% of subjects under 20 years old having with-the-rule (WTR) KA, and only 22.8% above 79 years old. The following regression equations were found between RA and KA: JRA0 = 0.73 × JKA0 − 0.18 (R = 0.78) and JRA45 = 0.70 × JKA45 + 0.04 (R = 0.69) and between RA and total corneal astigmatism (TCA): JRA0 = 0.73 × JTCA0 + 0.13 (R=0.78) and JRA45 = 0.70 × JTCA45 − 0.06 (R = 0.68) for the whole sample, but with sensible differences among age groups, both in the slope and in the intercept. Conclusion: Ignoring the age of the subject when using Javal’s rule could lead to an error in the final cylinder calculation that would increase in high astigmatisms. Applying this new power vector approach based on subject’s age could improve the accuracy of the astigmatism prediction.Item Influence of angle kappa on visual and refractive outcomes after implantation of a diffractive trifocal intraocular lens(Journal of cataract and refractive surgery, 2020) Garzón Jiménez, Nuria; García Montero, María; López Artero, Esther; Albarrán Diego, Cesar Antonio; Pérez Cambrodí, Rafael José; Illarramendi Mendicute, Igor; Poyales Galán, FranciscoPurpose: To evaluate changes in angle kappa following the implantation of a trifocal intraocular lens (IOL), and to assess the postoperative outcomes of patients with different angle kappa values. Setting: IOA Madrid Innova Ocular, Madrid, Spain Design: Prospective trial Methods: Sixty-three patients due to have bilateral implantation of the diffractive trifocal IOL (POD F, PhysIOL, Belgium) were included. Pupil offset was used as the best estimate of angle kappa and was measured using Pentacam (Oculus, Wetzlar, Germany) preoperatively and at 3-months after surgery. Postoperative refractive outcomes (sphere, cylinder, and MRSE) and visual outcomes at far, intermediate and near distance were assessed and compared between eyes with small pupil offset and eyes with large pupil offset. Quality of vision was assessed using a subjective questionnaire. Results: There was significant decrease in pupil offset post-operatively (mean: 0.197 ± 0.12 mm) compared to preoperatively (mean: 0.239 ± 0.12 mm), with a mean decrease of -0.042 mm (P = 0.0002). The same significant decrease was found for both the right eyes and left eyes, when analysed separately. No statistically significant difference was found in any of the refractive and visual acuity outcomes between eyes with small pupil offset and eyes with large pupil offset. The majority of patients (14 out of 16) complaining of significant halos had eyes with small pupil offset. Conclusion: Large pupil offset did not negatively affect visual and refractive outcomes. The tolerance to larger pupil offset might be due to the IOL optical design, with the first diffractive ring being larger than other commonly used multifocal IOLs. More studies comparing various diffractive IOL models will be useful to confirm such hypothesis.Item Optical Behavior of an Enhanced Monofocal Intraocular Lens Compared with a Standard One(Applied Sciences, 2023) Albarrán Diego, César; García Montero, María; Garzón Jiménez, Nuria; González Fernández, Verónica; Gómez Pedrero, José AntonioThe aim of this work was to compare an enhanced monofocal (RayOne EMV RAO200E, Rayner) and standard monofocal (RayOne RAO600C Aspheric, Rayner) intraocular lenses (IOLs) for three nominal powers (+10.00 D, +20.00 D and +30.00 D) as a function of the optical aperture diameter (pupil diameter) using a commercial Schlieren phase-shifting deflectometer NIMO TR1504 (Lambda-X, Belgium). From the wavefront maps measured by this instrument, the radial power profiles, the spherical aberration coefficients of the Zernike polynomial expansion (as a function of the optical aperture radius), and the root-mean-square (RMS) of the high-order aberrations (HOAs) were obtained and analyzed by comparing the two models. The results showed that the effective added power that could be obtained with the enhanced model depended directly on the pupil size and the power of the IOL implanted. The higher additions were achieved with the higher nominal IOL powers. The relationship between the pupil diameter, the corneal aberration of the patients and the power profile of these IOLs could have a crucial implication on the far distance and the final effective addition. However, it is important to note that these findings should be clinically validated through the implantation of these models in patients’ lenses.