Person: Rodríguez Vázquez, José Francisco
Universidad Complutense de Madrid
Faculty / Institute
Anatomía y Embriología
Anatomía y Embriología Humana
Now showing 1 - 10 of 19
PublicationElaboración de un manual de casos clínicos de anatomía radiológica aplicada de la extremidad inferior(2023-07-19) Aragonés Maza, Paloma; Maranillo Alcaide, Eva; Quiñones Garrido, Sara; Rodríguez Vázquez, José Francisco; Sañudo Tejero, José Ramón; Valderrama Canales, Francisco José; Vázquez Osorio, María Teresa; Viejo Tirado, Fermín PublicationElaboración de un sistema de evaluación continua y simultánea para todos los subgrupos prácticos de anatomía, mediante la aplicación Kahoot(2022-06-30) Maranillo Alcaide, Eva; Aragonés Maza, Paloma; Quiñones Garrido, Sara; Rodríguez Vázquez, José Francisco; Sañudo Tejero, José Ramón; Valderrama Canales, Francisco; Vázquez Osorio, Teresa; Viejo Tirado, FermínElaboramos una de serie de cuestionarios y retos sobre casos clínicos, imágenes radiológicas, técnicas de disección, relaciones anatómicas, etc. a través de la aplicación Kahoot, que nos han permitido evaluar a todos los alumnos de forma rápida, continua, simultánea y equitativa en cada una de las actividades que se desarrollan durante las prácticas de anatomía humana. A su vez, nos ha permitido controlar la asistencia, en cada una de las actividades, de forma rápida y veraz y detectar aquellos puntos de las prácticas que resultan más dificiles para nuestros alumnos. PublicationOrigin of the torus mandibularis: an embryological hypothesis(Wiley, 2013-11) Rodríguez Vázquez, José Francisco; Sakiyama, Koji; Verdugo López, Samuel; Amano, Osamu; Murakami, Gen; Abe, ShinichiTorus mandibularis, a well-known protuberance in the dental field, has been defined as a hyperostosis in the lingual aspect of the body of the mandible above the mylohyoid line. However, the origin of the torus mandibularis has not yet been clarified. The aim of this study was to provide a better understanding on the origin of the torus in view of the specific development of Meckel's cartilage at the site corresponding to the adult torus. A total of 40 mid-term human fetuses at 7-16 weeks of gestation were examined. The 10-13 weeks stage corresponded to the critical period in which Meckel's cartilage with endochondral ossification underwent a bending at the beginning of the intramandibular course. At the level of mental foramen, which was located between the deciduous canine and the first deciduous molar germs, the medial lamina of the mandible protruded medially to reach Meckel's cartilage. Thus, the medial lamina covered the posterior and superior aspect of the bending Meckel's cartilage just above the attachment of the developing mylohyoid muscle (i.e., in the oral cavity). We considered a bony prominence, which composed the protruding medial lamina and the bending Meckel's cartilage as the fetal origin of the torus mandibularis. A new theory is proposed for the origin of the torus mandibularis based on the existence of an anlage formed during the development of the mandible, variable in morphology and size, but always constant. PublicationDevelopment of the stapedius muscle and unilateral agenesia of the tendon of the stapedius muscle in a human fetus(Wiley, 2010-01) Rodríguez Vázquez, José Francisco; Mérida Velasco, José Ramón; Verdugo López, SamuelThe objective was to analyze the development of the stapedius muscle to understand an isolated unilateral absence of the tendon of the stapedius muscle in a human fetus. The study was made on 50 human embryos and fetuses aged 38 days to 17 weeks post-conception. The stapedius muscle was formed by two anlagen, one for the tendon, which derives from the internal segment of the interhyale and another for the belly, located in the second pharyngeal arch, medially to the facial nerve and near the interhyale. In the interhyale, two segments were observed forming an angle and delimited by the attachment of the belly of the stapedius muscle. The internal segment will form the tendon. The lateral segment of the interhyale was attached to the cranial end of the Reichert's cartilage (laterohyale), and normally it disappears at the beginning of the fetal period. The right unilateral agenesia of the tendon of the stapedius muscle, observed for the first time in a human fetus of 14 weeks post-conception development (PCd), was brought about by the lack of formation or the regression of the internal segment of the interhyale. It presented a belly of the stapedius muscle with an anomalous arrangement, and with a pseudo tendon originated by the persistence of the external segment of the interhyale. PublicationThe origin of the variations of the hyoid apparatus in human(Wiley, 2015-08) Rodríguez Vázquez, José Francisco; Verdugo López, Samuel; Abe, Hisroshi; Murakami, GenCurrently, theories based on acquired calcification of the stylohyoid ligament are believed to be a pathogenesis of syndromes associated with the hyoid apparatus (HA) and its variations. We studied the development of the HA from Reichert´s cartilage using serial sections of 25 human embryos and 45 fetuses. We ensured a fact that, at the initial stage, the HA appeared as two independent cartilage segments, that is, the cranial or styloid segment and the caudal or hyoid segment of Reichert's cartilage, those are connected by a mesenchymal structure. However, between 8 and 10 weeks of development, the mesenchymal connection was lost. We hypothesize that this disconnection is likely to be one of the major factors to make a descent of the hyoid bone in evolution. The stylohyoid ligament was not observed. The variations of the HA, should be considered variations of the development of Reicherts cartilage. If these variations are maintained in the adult, are likely to explain a major symptom associated with Eagle's syndrome. PublicationFetal topographical anatomy of the female urethra and descending vagina: a histological study of the early human fetal urethra(Elsevier, 2011-12) Masumoto, Hiroshi; Rodríguez Vázquez, José Francisco; Verdugo López, Samuel; Murakami, Gen; Matsubara, AkioBackground: Which parts of the male urethra correspond to the female urethra? To resolve this question, we need to understand fetal topographical changes in the urethra, its external sphincter and vagina. The vagina joins the mid-course of the primitive urethra and, later "descends" to the vaginal vestibulum. Methods: We examined histological sections of 14 female and 4 male mid-term fetuses. Results: The inferior end of the vagina was consistently embedded in the posterior wall of the urethra at 9-12 weeks. The supero-inferior level of the vaginal merging was lower in larger fetuses. Thus, the sequential variation in levels appeared to reflect the process of vaginal descent. However, in spite of penetration of the vaginal end into the posterior urethral wall, we found no sign of destruction of the urethral wall after vaginal descent in the low-merging types. Before vaginal descent, the female external sphincter extended posterolaterally around the urethra. Conclusion: The vaginal descent is classically regarded as a relative topographical change, but it is likely to be a result of elongation of the proximal urethra in the superior side of the vaginal merging. Conversely, the distal urethra is likely to be incorporated into the vaginal vestibulum by 15 weeks. During these processes, most of the female external sphincter seems to be expelled from the original anterior position into the vestibular wall as the urethrovaginal sphincter. The adult female urethra seems to correspond to the male prostatic urethra superior to the prostatic colliculus. PublicationGiant Aortic Arch Aneurysm and Cardio-vocal Syndrome: Still An Open-surgery Indication(Elmer Press, 2011-12) Garrido, José María; Esteban, María; Lara, Juan; Rodríguez Vázquez, José Francisco; Verdugo López, Samuel; López Checa, SalvadorThe Cardio-vocal Syndrome (Ortner's syndrome) is described as hoarseness due to the left recurrent laryngeal nerve palsy, caused by a specific cardiovascular pathology. In this case, we present a patient with a giant aortic arch aneurysm with an initial clinical presentation of Cardio-vocal Syndrome. The conventional open-surgery, instead of endovascular approach, was useful to control the morbidity from the compressive effect of adjacent structures, also preventing the aortic rupture. We strongly recommend analyzing carefully the individual case and the clinical targets to resolve, because the new technologies are not always the most effective therapeutic response. PublicationImmediate semi-static loading using compression healing abutments: A stability study in dogs(Elsevier, 2011-07-30) Cano Sánchez, Jorge; Campo Trapero, Julián; Colmenero, Cesar; Rodríguez Vázquez, José FranciscoEl objetivo de este estudio fue el de investigar el efecto que podía tener la aplicación de cargas laterales controladas de forma temprana, en la osteointegración de implantes dentales. Se analizaron los resultados obtenidos mediante análisis de frecuencia de resonancia (RFA), utilizando unos nuevos prototipos de pilares de compresión (patentados por los autores como modelo de utilidad*) y se demostró que dichas cargas controladas eran beneficiosas para mantener e incluso mejorar, la estabilidad de los implantes colocados durante los estadios iniciales de la cicatrización, acelerando el proceso de osteointegración final. *Modelo de Utilidad: “Pilares compresores perimplantarios”. Inventores: Cano J, Campo J, Bascones A. Número solicitud 200701862. Fecha publicación 1066151. PublicationMorphogenesis of the second pharyngeal arch cartilage (Reichert's cartilage) in human embryos(Wiley, 2006-02) Rodríguez Vázquez, José Francisco; Mérida Velasco, José Ramón; Verdugo López, Samuel; Sánchez Montesinos, Indalecio; Mérida Velasco, Juan AntonioThis study was performed on 50 human embryos and fetuses between 7 and 17 weeks of development. Reichert's cartilage is formed in the second pharyngeal arch in two segments. The longer cranial or styloid segment is continuous with the otic capsule; its inferior end is angulated and is situated very close to the oropharynx. The smaller caudal segment is in contact with the body and greater horn of the hyoid cartilaginous structure. No cartilage forms between these segments. The persistent angulation of the inferior end of the cranial or styloid segment of Reichert's cartilage and its important neurovascular relationships may help explain the symptomatology of Eagle's syndrome. PublicationPleuroperitoneal canal closure and the fetal adrenal gland(Wiley, 2011-04) Hayashi, Shogo; Fukuzawa, Yoshitaka; Rodríguez Vázquez, José Francisco; Baik, Hwan Cho; Verdugo López, Samuel; Murakami, Gen; Nakano, TakashiPleuroperitoneal canal (PP canal) closure is generally considered to result from an increase in the height, and subsequent fusion, of the bilateral pleuroperitoneal folds (PP folds). However, the folds develop in the area ventral to the adrenal, in contrast to the final position of the diaphragm, which extends to the dorsal side of the adrenal (the "retro-adrenal" diaphragm). We examined the semiserial histology of 20 human embryos and fetuses (crown-rump length 11-40 mm). We started observations of the canal at the stage through which the lung bud extends far caudally along the dorsal body wall to the level of the future adrenal, and the phrenic nerve has already reached the PP fold. Subsequently, the developing adrenal causes narrowing of the dorsocaudal parts of the canal, and provides the bilateral midsagittal recesses or "false" bottoms of the pleural cavity. However, at this stage, the PP fold mesenchymal cells are still restricted to the ventral side of the adrenal, especially along the liver and esophagus. Thereafter, in accordance with ascent of the lung, possibly due to anchoring of the liver to the adrenal, the PP fold mesenchymal cells seem to migrate laterally along the coelomic mesothelium covering some sheet-like loose mesenchymal tissue behind the adrenal. Final closure of the PP canal by lateral migration to provide the "retro-adrenal" diaphragm is a process quite different from the common dogma. It is likely that the sheet-like loose mesenchymal tissue becomes the caudal part of the pleural cavity through a process involving cell death.