López-Pintor Muñoz, Rosa María

Profile Picture
First Name
Rosa María
Last Name
López-Pintor Muñoz
Universidad Complutense de Madrid
Faculty / Institute
Especialidades Clínicas Odontológicas
UCM identifierORCIDScopus Author IDDialnet IDGoogle Scholar ID

Search Results

Now showing 1 - 10 of 12
  • Publication
    Análisis de casos clínicos en medicina oral mediante técnicas de escape room
    (2023-07-12) López-Pintor Muñoz, Rosa María; Bagán Debón, Leticia; Sarrión Pérez, Gracia; González Serrano, José; Arriba De La Fuente, Lorenzo De; Serrano Valle, Julia; Hernández Vallejo, Gonzalo; Iglesias Velázquez, Oscar; De Pedro Herráez, Miguel; Fernández Agra, María; Ibáñez Prieto, Elena; Vallina Fernández-Kelly, Carmen
    Las herramientas de gamificación motivan el aprendizaje. El escape room es un juego de moda. El objetivo de este proyecto es realizar diferentes escape room, basados en casos clínicos reales, para aplicar los conocimientos recibidos en la asignatura Medicina Bucal del grado en odontología.
  • Publication
    Lesiones orales en pacientes trasplantados renales y factores asociados a su aparición
    (Universidad Complutense de Madrid, Servicio de Publicaciones, 2009-03-16) López-Pintor Muñoz, Rosa María; Hernández Vallejo, Gonzalo; Andrés Belmonte, Amado; Arriba de la Fuente, Lorenzo de
  • Publication
    Efficacy and safety of a bioadhesive gel containing propolis extract, nanovitamin C and nanovitamin E on desquamative gingivitis: a double‑blind, randomized, clinical trial
    (Springer Nature, 2022-07-28) González Serrano, José; Serrano Valle, Julia; Sanz Alonso, Mariano; Torres García-Denche, Jesús; Hernández Vallejo, Gonzalo; López-Pintor Muñoz, Rosa María
    Objectives: To evaluate the efcacy of a gel-containing propolis extract, nanovitamin C, and nanovitamin E as adjuvants to professional plaque removal on desquamative gingivitis (DG). Materials and methods: A randomized clinical trial was conducted on patients sufering DG due to mucocutaneous diseases. Patients received professional supragingival prophylaxis with oral hygiene instructions and were randomly assigned to use test or control gels as toothpaste and to apply it on DG lesions 3 times/day for 4 weeks. DG clinical score (DGCS), clinical periodontal variables, and visual analog scale (VAS) for pain and oral health impact profle (OHIP-14) were collected at baseline, 2 and 4 weeks. Results: Twenty-two patients were randomly assigned to test (n=11) or control group (n=11). Eighteen had diagnosis of oral lichen planus and four of mucous membrane pemphigoid. DGCS statistically decreased in both groups after treatment with no signifcant diferences between groups. Clinical periodontal outcomes decreased in both groups, but no signifcant diferences were observed. Periodontal variables statistically improved only in test group after treatment. VAS and OHIP-14 scores decreased in test and control groups without signifcant diferences. However, only one test group showed a statistically signifcant decrease in VAS and OHIP-14 scores after treatment. No adverse efects were reported. Conclusions: Test gel may alleviate DG and improve quality of life without side efects. Clinical relevance: A gel-containing propolis extract, nanovitamin C, and nanovitamin E as adjuvants to mechanical debridement may improve both clinical and patient related outcomes in DG patients without side efects. Clinical trial registration. The study protocol was registered at with the following number: NCT05124366 on October 16, 2021.
  • Publication
    Salivary biomarkers in burning mouth syndrome: A systematic review and meta-analysis
    (Wiley, 2022-09-22) Fernández Agra, María; González Serrano, José; Pedro Herráez, Miguel de; Virto Ruiz, Leire; Caponio, Vito Carlo Alberto; Ibáñez Prieto, Elena; Hernández Vallejo, Gonzalo; López-Pintor Muñoz, Rosa María
    The objective of this systematic review was to evaluate which salivary biomarkers are altered in patients with burning mouth syndrome (BMS) compared to a control group (CG). A comprehensive literature search was conducted in four databases. Case– control studies evaluating salivary biomarkers in BMS patients were included. Risk of bias was assessed using the Newcastle-Ottawa tool. RevMan was used for metaanalysis. Seventeen studies were selected. The included studies collected 54 different biomarkers. Of these biomarkers, only three (cortisol, α-amylase, and dehydroepiandrosterone) were analyzed in three or more studies. Dehydroepiandrosterone obtained contradictory results among the studies. However, cortisol and α-amylase levels were found to be higher in BMS patients. Cortisol was the only biomarker which could be included for meta-analysis. Cortisol levels were significantly higher in the BMS group compared to the CG (Mean Difference = 0.39; 95% CI [0.14–0.65]; p = 0.003). In conclusion, different studies investigated salivary biomarkers in patients with BMS compared to a CG, with controversial results. Meta-analysis, confirmed by trial-sequential analysis, showed how cortisol levels were significantly higher in BMS. Cortisol emerges as an interesting salivary biomarker in BMS, but future properly designed studies are needed to evaluate its role in diagnosis and/or response to treatment.
  • Publication
    Xerostomia and Salivary Flow in Patients Taking Antihypertensive Drugs
    (MDPI, 2020) Ramírez Martínez-Acitores, Lucía; Hernández Ruiz de Azcárate, Fernando; Casañas, Elisabeth; Serrano Valle, Julia; Hernández Vallejo, Gonzalo; López-Pintor Muñoz, Rosa María
    The aims of this systematic review are (1) to compare the prevalence of xerostomia and hyposalivation between patients taking antihypertensive drugs with a control group (CG), (2) to compare salivary flow rate between patients treated with a CG, and (3) to identify which antihypertensives produce xerostomia. This systematic review was carried out according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. To evaluate methodological quality of the eligible studies Cochrane Collaboration tool for assessing the risk of bias for clinical trials and the modified Newcastle–Ottawa scale case-control studies were used. The databases were searched for studies up to November 19th 2019. The search strategy yielded 6201 results and 13 publications were finally included (five clinical trials and eight case-control studies). The results of the included studies did not provide evidence to state that patients taking antihypertensives suffer more xerostomia or hyposalivation than patients not taking them. With regard to salivary flow, only two clinical studies showed a significant decrease in salivary flow and even one showed a significant increase after treatment. The case–control studies showed great variability in salivary flow, but in this case most studies showed how salivary flow is lower in patients medicated with antihypertensive drugs. The great variability of antihypertensive drugs included, the types of studies and the outcomes collected made it impossible to study which antihypertensive drug produces more salivary alterations. The quality assessment showed how each of the studies was of low methodological quality. Therefore, future studies about this topic are necessary to confirm whether antihypertensive drugs produce salivary alterations.
  • Publication
    Usefulness of implementing the OHIP-14 questionnaire to assess the impact of xerostomia and hyposalivation on qualityof life in patients with primary Sjögren's syndrome
    (Wiley, 2022-08-23) Serrano Valle, Julia; López-Pintor Muñoz, Rosa María; Fernández Castro, Mónica; Ramírez Martínez-Acitores, Lucía; Sanz Alonso, Mariano; López, Javier; Blázquez, María Angeles; González, Jorge Juan; Hernández Vallejo, Gonzalo
    Background: The aim of this study is to analyze if the results of the Oral Health Impact Profile-14 questionnaire (OHIP-14) in patients with primary Sjögren's syndrome (pSS) are correlated with salivary flow and level of xerostomia. Methods: This observational cross-sectional study was conducted in 61 patients (60 women, one man, mean age 57.64 [13.52]) diagnosed of pSS according to the American-European Criteria (2002). After recording demographic, medical and dental data (decayed-missing-filled teeth index [DMFT]), unstimulated (UWS) and stimulated (SWS) salivary flows were collected. Subsequently, UWS flow was categorized into two groups (0.7 ml/min). Patients also filled out a visual analog scale (VAS) for xerostomia and OHIP-14 for self-reported quality of life (QoL). Results: Data showed positive and significant correlation between OHIP-14 and xerostomia, based on VAS results (r = 0.52; p = 0.001). Furthermore, there was a negative correlation between UWS and OHIP-14 scores (r = -0.34; p = 0.006) and VAS for xerostomia (r = -0.22; p = 0.09). No significant correlation was found between SWS and OHIP-14 or VAS neither between DMFT and OHIP-14. When assessing the level of QoL by the UWS and SWS flow categories a significant association was found for UWS (p = 0.001) but not for SWS (p = 0.11). The OHIP-14 values were higher in the groups with lower salivary flow. The multiple linear regression to predict OHIP-14 only selected VAS for xerostomia as a statistically significant predictor. Conclusions: Increased level of xerostomia and reduced UWS flow decrease oral health-related QoL in patients with pSS.
  • Publication
    Aprendizaje basado en juegos online para la mejora de la adquisición de competencias en Patología Médica Bucal
    (2021-06-29) López-Pintor Muñoz, Rosa María; Hernández Vallejo, Gonzalo; de Arriba de la Fuente, Lorenzo; González Serrano, José; Casañas Gil, Elisabeth; de Pedro Herráez, Miguel; Serrano Valle, Julia; Ramírez Martínez-Acitores, Lucía; Iglesias Velázquez, Óscar; Serrano Zamora, Rebeca; Vallina Fernández-Kelly, Carmen; Paredes Rodríguez, Víctor Manuel; García Rodríguez, María Dolores
    Estamos viviendo una situación complicada debido a la pandemia por el COVID-19. Durante el presente curso académico parte de nuestras asignaturas han pasado de una docencia presencial a una docencia online, esto ha sucedido en la asignatura Patología Médica Bucal del grado en Odontología. Este paso de la presencialidad a la docencia online requiere de nuevas medidas de motivación para aumentar la adquisición de conocimientos y mantener el aprendizaje activo. El objetivo de este proyecto ha sido aplicar diferentes juegos online para mejorar el aprendizaje en Patología Médica Bucal y la transferencia de conocimiento entre alumnos y profesores.
  • Publication
    Development of a program of mixed radiolucent-radiopaque lesions imaging via radiographic cases for active learning in oral medicine
    (2017) López-Pintor Muñoz, Rosa María; Hernández Vallejo, Gonzalo; Ortega Aranegui, Ricardo; Paredes Rodríguez, Víctor Manuel; de Arriba de la Fuente, Lorenzo; Casañas Gil, Elisabeth; Ramírez Martínez-Acitores, Lucia; Serrano Valle, Julia
    A través del presente proyecto se ha creado un fichero de imágenes radiográficas mixtas (radiopacas-radiolucidas) que serán utilizadas por los alumnos del tercer curso de Grado de la asignatura Medicina Bucal a fin de mejorar la enseñanza práctica del apartado lesiones radiográficas de los maxilares. Dichos ficheros se incorporarán al Campus Virtual para que el alumno pueda hacer uso de ellos. La elaboración de un fichero de estas características ha exigido en primer lugar la selección de las imágenes radiográficas mixtas de los maxilares más representativas. Se han seleccionado 43 imágenes radiográficas mixtas que se han clasificado en “Mixed Radiolucent-Radiopaque periapical lesions” (15 imágenes), “Mixed Radiolucent-Radiopaque pericoronal lesions” (8 imágenes) y “Mixed Radiolucent-Radiopaque lesions not necessarily contacting teeth“ ( 20 imágenes). Se han realizado 4 flowchart (el tercer grupo se subdividió en dos) para esquematizar las lesiones mixtas más frecuentes con sus características clínicas y radiográficas más habituales. Dichos flowchart ayudarán al alumno a poder llegar al diagnóstico de las lesiones de los casos clínicos seleccionados, cuya historia clínica también se ha reflejado. Todo el trabajo se ha realizado en dos idiomas inglés y español, que ayudará a los alumnos a aprender el vocabulario en inglés relacionado con el tema. Además, facilitará la comprensión de los alumnos de otras nacionalidades que pueden acudir a nuestra facultad y ayudará a los alumnos de la UCM que acuden a otras universidades Europeas o Americanas.
  • Publication
    Enseñanza no presencial de la asignatura patología bucal a través de la presentación de artículos científicos en inglés
    (2018-06-27) López-Pintor Muñoz, Rosa María; Hernández Vallejo, Gonzalo; de Arriba de la Fuente, Lorenzo; Casañas Gil, Elizabeth; Ramírez Martínez-Acitores, Lucía; Serrano Valle, Julia; de Pedro Herráez, Miguel
    Elaboración de un dossier de artículos en Inglés en relación a cada unidad temática de la asignatura Patología Médica Bucal. Los artículos se presentarán al alumnado tras la clase magistral de cada área temática para fomentar la docencia “no presencial”.
  • Publication
    Realización de folletos informativos acerca de la patología de la mucosa oral para informar a pacientes y profesionales sanitarios
    (2019-06-12) López-Pintor Muñoz, Rosa María; Hernández Vallejo, Gonzalo; Arriba de la Fuente, Lorenzo de; Somacarrera Pérez, María Luisa; López Sánchez, Antonio Francisco; González Serrano, José; Casañas Gil, Elizabeth; Ramírez Martínez-Acitores, Lucía; Serrano Valle, Julia; Pedro Herráez, Miguel de
    Elaboración de folletos informativos acerca de la patología de la mucosa oral más relevante para informar a pacientes y colectivos médico-sanitarios. El trabajo será realizado por los alumnos de la asignatura Patología Médica Bucal de tercer curso de Odontología. Los trípticos se realizarán para fomentar la docencia “no presencial” y el tipo de trabajo será de aprendizaje por proyectos. Este trabajo comprometerá al alumno emocional y afectivamente con su aprendizaje ya que ayudará a diagnosticar y tratar de forma temprana dichas patologías. Los alumnos de la asignatura Medicina Bucal realizarán folletos acerca de la Patología de la Mucosa Oral para informar a pacientes y colectivos sanitarios. Se fomentará la docencia no presencial, el tipo de trabajo será de aprendizaje por proyectos