Person:
Maranillo Alcaide, Eva

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First Name
Eva
Last Name
Maranillo Alcaide
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Medicina
Department
Anatomía y Embriología
Area
Anatomía y Embriología Humana
Identifiers
UCM identifierORCIDScopus Author IDWeb of Science ResearcherIDDialnet ID

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Now showing 1 - 4 of 4
  • Item
    Connections between postparotid terminal branches of the facial nerve: An immunohistochemistry study
    (Clinical Anatomy, 2022) Martínez Pascual, Paula; Pérez Lloret, Pilar; Maranillo Alcaide, Eva; Sanz García, Carlos; Simón de Blas, Clara; Sañudo Tejero, José Ramón; Konschake, Marko; Porzionato, Andrea; De Caro, Raffaele; Macchi, Veronica
    It has been assumed that connections between the postparotid terminal branches of the facial nerve are purely motor. However, the nature of their fibers remains unexplored. The aim of this study is to determine whether these connections comprise motor fibers exclusively. In total 17 connections between terminal facial nerve branches were obtained from 13 different facial nerves. Choline acetyltransferase antibody (ChAT) was used to stain the fibers in the connections and determine whether or not all of them were motor. All connections contained ChAT positive and negative fibers. The average number of fibers overall was 287 (84–587) and the average proportion of positive fibers was 63% (37.7%–91.5%). In 29% of the nerves, >75% of the fibers were ChAT+ (strongly positive); in 52.94%, 50%–75% were ChAT+ (intermediately positive); and in 17.65%, <50% were ChAT+ (weakly positive). Fibers traveling inside the postparotid terminal cranial nerve VII branch connections are not exclusively motor.
  • Item
    The bronchial segmentation and its anatomical variations. A clinical-anatomic and bronchoscopy study
    (Annals of Anatomy, 2021) Martín Ruiz, Silvia; Gutiérrez Collar, Christian; Forcén Vicente De Vera, Elena; Bernabé Barrios, María José; Simón de Blas, Clara; Konschake, Marko; Sañudo Tejero, José Ramón; Maranillo Alcaide, Eva
    The development in interventional respiratory medicine entails the need of bronchial anatomical knowledge, whose variations assume their greatest importance nowadays. The aim of this study was to describe the frequency of these variations and to analyze the bronchial lengths, barely registered before in literature. This observational descriptive study (from June 2018 until April 2019) was conducted in a sample of 17 pairs of lungs, which were dissected and measured at the Cadaver Donation Centre (Universidad Complutense, Madrid), and a second sample of 50 bronchoscopies, performed at the San Carlos Clinic Hospital, which were analyzed during the procedure. Our results show that there are no significant differences in the incidence of variations by sex in any of both samples, and neither in the average length of any bronchus by sex nor lobar pattern. Left main bronchus presents the longest length and left upper lobe bronchus the shortest. The highest percentage of variations is contained in the right lower lobe (25.4%), and the most frequent variation in the subsuperior bronchus (B*) (19.4%). The middle lobe and the left lower lobe present the lowest percentage of variations (11.9%). Only 37.3% of the pairs of lungs/patients did not have any anatomical variation in the general sample. Despite of the small size of the sample, results show a high percentage of variations and a minority of completely normal pairs of lungs, which invites us to reflect about the probable high prevalence of variations in the general population. Further studies with greater samples are needed to confirm our hypothesis.
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    Atheromatosis of the brain-supplying arteries: Circle of Willis, basilar, vertebral and their branches
    (Annals of Anatomy, 2022) Llopis, Guillermo; Quinones, Sara; Konschake, Marko; Simon De Blas, Clara; Hernández, Lorenzo Mauricio; Abramovic, A; Viñuela Prieto, José Manuel; Sañudo Tejero, José Ramón; Tubbs, Richard Shane; Maranillo Alcaide, Eva
    Purpose: Atherosclerotic plaques in the brain-supplying arteries are slowly-developing alterations of vascular structures that can lead to neurological impairment due to stenosis and insufficient oxygenation of eloquent brain areas. The aim of this study is to provide detailed demographic information related to the incidence of atherosclerotic plaques in the cerebral arteries. Material and methods: Forty-eight circles of Willis (21 men, 21 women, mean age: 70.26, six samples unknown) were macroscopically analyzed for length, diameter, and presence of atherosclerotic plaques. Statistical analysis was used to identify potential differences in the locations and frequencies of atherosclerotic plaques in relation to age and sex. Results: The study sample revealed 261 atherosclerotic plaques. The key findings were significant correlations between plaque development and age and between plaque location and age; however, there was no significant sex difference. Conclusion: The upper and lower branches of the middle cerebral artery (MCA) were novel locations predisposing to plaque development. A cut-off value at 60 years revealed a significant difference in plaque development and distribution. There were no significant sex differences in the occurrence of atherosclerotic plaques.
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    The carotid axis revisited
    (Scientific reports, 2021) Cobiella, R; Quinones, S; Konschake, Marko; Aragonés Maza, Paloma; Leon Vintró, Xavier; Vázquez Osorio, María Teresa; Sañudo Tejero, José Ramón; Maranillo Alcaide, Eva
    The aim was to determine the variations in the level of origin of carotid bifurcation and diameters of the common, internal, and external carotid arteries which is clinically important for several interventional procedures. Therefore, 165 human embalmed corpses were dissected. The data collected were analyzed using the Chi square-test and the Pearson correlation test. The results of previous studies have been reviewed. In relation to the level of the carotid bifurcation, taking as a reference point the hyoid bone, the values ranged from 4 cm below the hyoid body to 2.5 cm above the body of the hyoid, being the average height—0.33 cm, with a standard deviation of 1.19 cm. The right carotid bifurcation was established at a higher level (x = − 0.19 cm.) than the left one (x = − 0.48 cm.) (p = 0.046). On the contrary, no significant gender differences could be observed. The arterial calibres of the common and internal carotid arteries were higher in male than female. In the internal carotid artery (X = 0.76 cm.), the left was greater than the right (X = 0.72 cm.) (P = 0.047). However, no differences in the distribution of the calibre of the external carotid artery were found neither by side nor gender. Variations in the level of bifurcation and calibres of carotid arteries are relevant for interventional radiology procedures and head and neck surgeries. Knowledge of these anatomical references might help clinicians in the interpretation of the carotid system.