Person:
Navia Lombán, Beatriz

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First Name
Beatriz
Last Name
Navia Lombán
Affiliation
Universidad Complutense de Madrid
Faculty / Institute
Farmacia
Department
Nutrición y Ciencia de los Alimentos
Area
Nutrición y Bromatología
Identifiers
UCM identifierORCIDScopus Author IDWeb of Science ResearcherIDDialnet IDGoogle Scholar ID

Search Results

Now showing 1 - 8 of 8
  • Publication
    El uso de podcasts y vídeos subtitulados como herramientas didácticas e integradoras en el Grado de Farmacia y Nutrición Humana y Dietética
    (2018-06-19) Aparicio Vizuete, Aránzazu; López sobaler, Ana María; Rodríguez Rodríguez, Elena; Ortega Anta, Rosa María; Andrés Carvajales, Pedro; Navia Lombán, Beatriz; Rodríguez Moreno, Pilar; Cuadrado Soto, Esther; Peral Suárez, África
  • Publication
    Herramienta Kahoot como estrategia para fomentar la participación y el aprendizaje activo del alumno
    (2017) Rodríguez Rodríguez, Elena; Aparicio Vizuete, Aránzazu; López Sobaler, Ana María; Ortega Anta, Rosa María; Navia Lombán, Beatriz; Andrés Carvajales, Pedro; Ródenas de la Rocha, Sofía; Martín Gómez, María del Carmen; Rodríguez Moreno, María Pilar; Cuadrado Soto, Juana Esther
  • Publication
    Pasapalabra en el Grado de Farmacia y Nutrición Humana y Dietética
    (2015-01-28) Aparicio Vizuete, Aránzazu; Rodríguez Rodríguez, Elena; Ortega Anta, Rosa Mª; Navia Lombán, Beatriz; Andrés Carvajales, Pedro
  • Publication
    Jornadas Científicas sobre: “Técnicas analíticas utilizadas para la determinación de nutrientes y fitoquímicos de importancia clínica y alimentaria”
    (2016-02-10) Rodriguez Rodriguez, Elena; Sanchez Paniagua-López, Marta; López Ruiz, Beatriz; Hervás Pérez, Juan Pablo; Andrés Carvajales, Pedro; Mateos Aparicio, Inmaculada; Tenorio Sanz, Maria Dolores; Redondo Cuenca, Araceli; Aparicio Vizuete, Aránzazu; Navia Lombán, Beatriz; López Sobaler, Ana María; Ortega Anta, Rosa María
  • Publication
    Fecal microbiota transplantation in HIV: A pilot placebo-controlled study
    (Springer Nature, 2021-02-18) Serrano-Villar, Sergio; Talavera-Rodríguez, Alba; Gosalbes, María José; Madrid, Nadia; Pérez-Molina, José Antonio; Elliott, Ryan J; Navia Lombán, Beatriz; Lanza, Val F; Vallejo, Alejandro; Osman, Majdi; Dronda, Fernando; Budree, Shrish; Zamora, Javier; Gutiérrez, Carolina; Manzano, Mónica; Vivancos, María Jesús; Ron, Raquel; Martínez-Sanz, Javier; Herrera, Sabina; Ansa, Uxua; Moya, A; Moreno, Santiago
    Changes in the microbiota have been linked to persistent inflammation during treated HIV infection. In this pilot double-blind study, we study 30 HIV-infected subjects on antiretroviral therapy (ART) with a CD4/CD8 ratio < 1 randomized to either weekly fecal microbiota capsules or placebo for 8 weeks. Stool donors were rationally selected based on their microbiota signatures. We report that fecal microbiota transplantation (FMT) is safe, not related to severe adverse events, and attenuates HIV-associated dysbiosis. FMT elicits changes in gut microbiota structure, including significant increases in alpha diversity, and a mild and transient engraftment of donor’s microbiota during the treatment period. The greater engraftment seems to be achieved by recent antibiotic use before FMT. The Lachnospiraceae and Ruminococcaceae families, which are typically depleted in people with HIV, are the taxa more robustly engrafted across time-points. In exploratory analyses, we describe a significant amelioration in the FMT group in intestinal fatty acid-binding protein (IFABP), a biomarker of intestinal damage that independently predicts mortality. Gut microbiota manipulation using a non-invasive and safe strategy of FMT delivery is feasible and deserves further investigation. Trial number: NCT03008941.
  • Publication
    Interactions among the mycobiome, bacteriome, inflammation, and diet in people living with HIV
    (Taylor&Francis Online, 2022-06-23) Gosalbes, María José; Jiménez-Hernández, Nuria; Moreno, Elena; Artacho, Alejandro; Pons, Xavier; Ruíz-Pérez, Sonia; Navia Lombán, Beatriz; Estrada, Vicente; Talavera-Rodríguez, Alba; Madrid, Nadia; Vallejo, Alejandro; Luna, Laura; Pérez-Molina, José Antonio; Moreno, Santiago; Serrano-Villar, Sergio
    While the intestinal microbiome seems a major driver of persistent immune defects in people with HIV (PWH), little is known about its fungal component, the mycobiome. We assessed the inter-kingdom mycobiome–bacteriome interactions, the impact of diet, and the association with the innate and adaptive immunity in PWH on antiretroviral therapy. We included 24 PWH individuals and 12 healthy controls. We sequenced the Internal Transcribed Spacer 2 amplicons, determined amplicon sequence variants, measured biomarkers of the innate and adaptive immunity in blood and relations with diet. Compared to healthy controls, PWH subjects exhibited a distinct and richer mycobiome and an enrichment for Debaryomyces hansenii, Candida albicans, and Candida parapsilosis. In PWH, Candida and Pichia species were strongly correlated with several bacterial genera, including Faecalibacterium genus. Regarding the links between the mycobiome and systemic immunology, we found a positive correlation between Candida species and the levels of proinflammatory cytokines (sTNF-R2 and IL-17), interleukin 22 (a cytokine implicated in the regulation of mucosal immunity), and CD8+ T cell counts. This suggests an important role of the yeasts in systemic innate and adaptive immune responses. Finally, we identified inter-kingdom interactions implicated in fiber degradation, short-chain fatty acid production, and lipid metabolism, and an effect of vegetable and fiber intake on the mycobiome. Therefore, despite the great differences in abundance and diversity between the bacterial and fungal communities of the gut, we defined the changes associated with HIV, determined several different inter-kingdom associations, and found links between the mycobiome, nutrient metabolism, and systemic immunity
  • Publication
    Chagas disease is related to structural changes of the gut microbiota in adults with chronic infection (TRIPOBIOME Study)
    (PLOS MEDICINE COLLECTION, 2023-07-21) Pérez-Molina, José Antonio; Crespillo-Andújar, Clara; Trigo, Elena; Chamorro, Sandra; Arsuaga, Marta; Olavarrieta, Leticia; Navia Lombán, Beatriz; Martín, Ohiane; Monje-Maillo, Begoña; Norman, Francesca F; Lanza, Val F; Serrano-Villar, Sergio
    Background The implications of the gut microbial communities in the immune response against parasites and gut motility could explain the differences in clinical manifestations and treatment responses found in patients with chronic Chagas disease. Methodology/Principal findings In this pilot prospective cross-sectional study, we included 80 participants: 29 with indeterminate CD (ICD), 16 with cardiac CD (CCD), 15 with digestive CD (DCD), and 20 controls without CD. Stool was collected at the baseline visit and faecal microbial community structure DNA was analyzed by whole genome sequencing. We also performed a comprehensive dietary analysis. Ninety per cent (72/80) of subjects were of Bolivian origin with a median age of 47 years (IQR 39–54) and 48.3% (29/60) had received benznidazole treatment. There were no substantial differences in dietary habits between patients with CD and controls. We identified that the presence or absence of CD explained 5% of the observed microbiota variability. Subjects with CD exhibited consistent enrichment of Parabacteroides spp, while for Enterococcus hirae, Lactobacillus buchneri and Megamonas spp, the effect was less clear once excluded the outliers values. Sex, type of visceral involvement and previous treatment with benznidazole did not appear to have a confounding effect on gut microbiota structure. We also found that patients with DCD showed consistent Prevotella spp enrichment. Conclusions We found a detectable effect of Chagas disease on overall microbiota structure with several potential disease biomarkers, which warrants further research in this field. The analysis of bacterial diversity could prove to be a viable target to improve the prognosis of this prevalent and neglected disease.
  • Publication
    Physical activity practice and sports preferences in a group of Spanish schoolchildren depending on sex and parental care: a gender perspective
    (Springer Nature, 2020-07-07) Peral Suárez, África; Cuadrado Soto, Esther; Perea Sánchez, José Miguel; Navia Lombán, Beatriz; López Sobaler, Ana María; Ortega Anta, Rosa María
    Background: Physical activity plays an important role in the maintenance of health, and it is especially important during childhood. However, the lack of information about differences in physical activity practice and sports preferences of children considering gender differences can result in non-effective policies that enhance inequalities between sexes. The aim of this study is to identify the sports preferences of Spanish schoolchildren and their physical activity practice behaviors depending on their sex and their parental care, analyzing the possible differences from a gender perspective. Method: Three hundred sixty-four Spanish schoolchildren (179 girls, 185 boys) participated in this cross-sectional study. A daily physical activity questionnaire was used to evaluate physical activity level (PAL), moderate-to-vigorous physical activity (MVPA) and sports preferences and a socio-health questionnaire were used to collect data about parental care. Statistical analysis was performed using SPSS and applying Student’s T-test for normal variables, Mann-Whitney U-test for non-parametrical variables, and chi-square (χ2) test for categorical variables. Subsequently, odds ratios were used to analyze associations between the physical activity practice of the children and parental care. Results: PAL and time spent in MVPA was significantly lower for girls compared to boys (1.44 ± 0.07 vs. 1.46 ± 0.07, p < 0.001 and 0.74 ± 0.40 h/day vs. 0.90 ± 0.45 h/day; p < 0.001, respectively). Dancing, rhythmic gymnastics, skating, and water sports were practiced more by girls, while football, wrestling sports, handball, and racket sports were practiced more by boys (p < 0.05). Children cared for by their fathers had higher odds for physical activity practice (OR = 1.995 (1.202–3.310), p = 0.008). Conclusion: Physical activity among girls was less frequent and less intense. Girls opted for individual sports with artistic connotations, while boys often practiced more team contact sports. Furthermore, children are more physically actives when their father is in charge of them