Visual suppression in intermittent exotropia during binocular alignment.
dc.contributor.author | Serrano Pedraza, Ignacio | |
dc.contributor.author | Manjunath, Vina | |
dc.contributor.author | Osunkunle, Olaoluwakitan | |
dc.contributor.author | Clarke, Michael P | |
dc.contributor.author | Read, Jenny C A | |
dc.date.accessioned | 2023-06-20T04:08:11Z | |
dc.date.available | 2023-06-20T04:08:11Z | |
dc.date.issued | 2011-04 | |
dc.description.abstract | PURPOSE To investigate the cortical mechanisms that prevent diplopia in intermittent exotropia (X(T)) during binocular alignment (orthotropia). METHODS The authors studied 12 X(T) patients aged 5 to 22 years. Seventy-five percent had functional stereo vision with stereoacuity similar to that of 12 age-matched controls (0.2-3.7 min arc). Identical face images were presented to the two eyes for 400 ms. In one eye, the face was presented at the fovea; in the other, offset along the horizontal axis with up to 12° eccentricity. The task was to indicate whether one or two faces were perceived. RESULTS All X(T) patients showed normal diplopia when the nonfoveal face was presented to nasal hemiretina, though with a slightly larger fusional range than age-matched controls. However, 10 of 12 patients never experienced diplopia when the nonfoveal face was presented to temporal hemiretina (i.e., when the stimulus simulated exodeviation). Patients showed considerable variability when the single image was perceived. Some patients suppressed the temporal stimulus regardless of which eye viewed it, whereas others suppressed a particular eye even when it viewed the foveal stimulus. In two patients, the simulated exodeviation might have triggered a shift from normal to anomalous retinal correspondence. CONCLUSIONS Antidiplopic mechanisms in X(T) can be reliably triggered by purely retinal information during orthotropia, but the nature of these mechanisms varies between patients. | |
dc.description.department | Depto. de Psicología Experimental, Procesos Cognitivos y Logopedia | |
dc.description.faculty | Fac. de Psicología | |
dc.description.refereed | TRUE | |
dc.description.sponsorship | Royal Society | |
dc.description.sponsorship | Medical Research Council | |
dc.description.status | pub | |
dc.eprint.id | https://eprints.ucm.es/id/eprint/36287 | |
dc.identifier.citation | Govindan M, Mohney BG, Diehl NN, Burke JP. Incidence and types of childhood exotropia: a population-based study. Ophthalmology. 2005;112:104 –108. Von Noorden G, Campos EC. Binocular Vision and Ocular Motility: Theory and Management of Strabismus. St. Louis: Mosby-Year Book; 2002. Jampolsky A. Differential diagnostic characteristics of intermittent exotropia and true exophoria. Am Orthoptic J. 1954;4:48 –55. Cooper J, Medow MD. Major review: intermittent exotropia; basic and divergence excess type. Binocular Vis Eye Muscle Surg Q. 1993;8:185–216. Pratt-Johnson JA, Wee HS. Suppression associated with exotropia. Can J Ophthalmol. 1969;4:136 –144. Awaya S, Nozaki H, Itoh T, Harada K. Studies of suppression in alternating constant exotropia and intermittent exotropia with reference to effects of fusional background. In: Moore S, Mein J, Stockbridge L, eds. Orthoptics: Past, Present, and Future. New York: Stratton Intercontinental Medical Book Co.; 1976:531– 546. Pritchard C, Flynn JT. Suppression of physiologic diplopia in intermittent exotropia. Am Orthoptic J. 1981;31:72–79. Melek MD, Shokida MD, Dominguez MD, Zabalo MD. Intermittent exotropia: a study of suppression in the binocular visual field in 21 cases. Binocular Vis Strabismus Q. 1992;7:25–30. Cooper J, Feldman J, Pasner K. Intermittent exotropia: stimulus characteristics affect tests for retinal correspondence and suppression. Binocular Vis Strabismus Q. 2000;15:131–140. Cooper J, Record CD. Suppression and retinal correspondence in intermitent exotropia. Br J Ophthalmol. 1986;70:673– 676. Cooper J, Feldman J. Panoramic viewing, visual acuity of the deviating eye and anomalous retinal correspondence in the intermittent exotropia of the divergence excess type. Am J Optom Psychol Opt. 1979;56:422– 429. Serrano-Pedraza I, Read JCA. Stereo vision requires an explicit encoding of vertical disparity. J Vis. 2009;9:1–13. Pelli DG. The VideoToolbox software for visual psychophysics: transforming numbers into movies. Spat Vis. 1997;10:437– 442. Brainard DH. The psychophysics toolbox. Spat Vis. 1997;10:433– 436. Pentland A. Maximum likelihood estimation: the best PEST. Percept Psychophys. 1980;28:377–379. Emerson PL. Observations on maximum-likelihood and Bayesian methods of forced-choice sequential threshold estimation. Percept Psychophys. 1986;39:151–153. García-Pérez MA. Forced-choice staircases with fixed steps sizes: asymptotic and small-sample properties. Vis Res. 1998; 38:1861– 1881. King-Smith PE, Grigsby SS, Vingrys AJ, Benes SC, Supowit A. Efficient and unbiased modifications of the QUEST threshold method: theory, simulations, experimental evaluation and practical implementation. Vis Res. 1994; 34:885–912. Anderson AJ. Utility of a dynamic termination criterion in the ZEST adaptive threshold method. Vis Res. 2003;43:165–170. Stathacopoulos RA, Rosenbaum AL, Zanoni D, et al. Distance stereoacuity: assessing control in intermittent exotropia. Ophthalmology. 1993; 100:495–500. Yildirim C, Altinsoy HI, Yakut E. Distance stereoacuity norms for the mentor B-VAT II-SG video acuity tester in young children and young adults. J AAPOS. 1998; 2:26 –32. Yildirim C, Mutlu FM, Chen Y, Altinsoy HI. Assessment of central and peripheral fusion and near and distance stereoacuity in intermittent exotropic patients before and after strabismus surgery. Am J Ophthalmol. 1999; 128:222–230. Sharma P, Saxena R, Narvekar M, Gadia R, Menon V. Evaluation of distance and near stereoacuity and fusional vergence in intermittent exotropia. Ind J Ophthalmol. 2008; 56:121–125. Hatt SR, Haggerty H, Buck D, Adams W, Strong NP, Clarke MP. Distance stereoacuity in intermittent exotropia. Br J Ophthalmol. 2007; 91:219 –221. Baker JD, Davies GT. Monofixational Intermittent Exotropia. Arch Ophthalmol. 1979;97:93–95. Joosse MV, Simonsz HJ, Spekreijse H, Mulder PGH, Minderhout HM. The optimal stimulus to elicit suppression in small-angle convergent strabismus. Strabismus. 2000b; 8:233–242. Campos EC. Binocularity in comitant strabismus: binocular visual fields studies. Doc Ophthalmol. 1982; 53:249 –281. Jampolsky A. Characteristics of suppression in strabismus. Arch Ophthalmol. 1955;54: 683– 696. Travers Ta`B. Suppression of vision in squint and its association with retinal correspondence and amblyopia. Br J Ophthalmol. 1938; 22:577– 604. Schor C. Zero retinal image disparity: stimulus for suppression in small-angle strabismus. Doc Ophthalmol. 1978; 46:149 –160. Schor CM. Visual stimuli for strabismic suppression. Perception. 1977; 6:583–593. Kilwinger S, Spekreijse H, Simonsz HJ. Strabismic suppression depends on the amount of dissimilarity between left- and right-eye images. Vis Res. 2002; 42:2005–2011. Ogle KN, Dyer JA. Some observations on intermittent exotropia. Arch Ophthalmol. 1965; 73:58–73. Campos EC, Chiesi C. Perimetrie binoculaire dans l’exotropie concomitant. Bull Soc Fr Ophthalmol. 1980; 92:301–307. Ramachandran VS, Cobb S, Levi L. The neural locus of binocular rivalry and monocular diplopia in intermittent exotropes. NeuroReport. 1994; 5:1141–1144. Jie Y, Xu ZY, He YN, et al. A 4 year retrospective survey of strabismus surgery in Tongren Eye Centre Beijing. Ophthalmic Physiol Opt. 2010; 30:310–314. Zhang ZL, Cantor CR, Schor CM. Perisaccadic stereo depth with zero retinal disparity. Curr Biol. 2010; 20:1176 –1181. | |
dc.identifier.doi | 10.1167/iovs.10-6144 | |
dc.identifier.issn | 1552-5783 | |
dc.identifier.officialurl | http://dx.doi.org/10.1167/iovs.10-6144 | |
dc.identifier.relatedurl | http://iovs.arvojournals.org/article.aspx?articleid=2127016 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14352/44954 | |
dc.issue.number | 5 | |
dc.journal.title | Investigative ophthalmology & visual science | |
dc.language.iso | eng | |
dc.page.final | 64 | |
dc.page.initial | 2352 | |
dc.relation.projectID | Research Fellowship UF041260 (JCAR) | |
dc.relation.projectID | New Investigator Award 80154 (JCAR) | |
dc.rights | Atribución-NoComercial 3.0 España | |
dc.rights.accessRights | open access | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/3.0/es/ | |
dc.subject.cdu | 159.9.07 | |
dc.subject.cdu | 159.93 | |
dc.subject.cdu | 535 | |
dc.subject.keyword | Child | |
dc.subject.keyword | diplopia | |
dc.subject.keyword | Face | |
dc.subject.keyword | Perception | |
dc.subject.keyword | Eye | |
dc.subject.keyword | Nose | |
dc.subject.keyword | Niño | |
dc.subject.keyword | Miopía | |
dc.subject.keyword | Cara | |
dc.subject.keyword | Percepción visual | |
dc.subject.keyword | Ojo | |
dc.subject.keyword | Nariz | |
dc.subject.ucm | Psicología experimental | |
dc.subject.ucm | Percepción | |
dc.subject.ucm | Óptica oftálmica | |
dc.subject.unesco | 6106 Psicología Experimental | |
dc.subject.unesco | 6106.09 Procesos de Percepción | |
dc.title | Visual suppression in intermittent exotropia during binocular alignment. | |
dc.type | journal article | |
dc.volume.number | 52 | |
dspace.entity.type | Publication | |
relation.isAuthorOfPublication | 0fc94368-bbc4-426b-915d-34d2e98197db | |
relation.isAuthorOfPublication.latestForDiscovery | 0fc94368-bbc4-426b-915d-34d2e98197db |
Download
Original bundle
1 - 1 of 1