Correlation between kinematic parameters, ataxia and ground-to-lip distance in detomidine sedated horses

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dc.contributor.authorIzquierdo Moreno, Jorge
dc.contributor.authorIllán de Paz, Marta
dc.contributor.authorManso Díaz, Gabriel
dc.contributor.authorVillalba Orero, María
dc.contributor.authorLópez San Román, Francisco Javier
dc.date.accessioned2024-09-03T13:36:54Z
dc.date.available2024-09-03T13:36:54Z
dc.date.issued2024-08-14
dc.description.abstractBackground An accurate evaluation of the degree of sedation is mandatory to adjust the dosage of sedative drugs. Objectives To determine the correlation between head height above the ground and ataxia degree in horses sedated with detomidine and the correlation existing between accelerometric variables and both parameters. Study design Retrospective study. Methods Twelve horses were given 0.01 mg/kg of detomidine hydrochloride iv. Measured accelerometric parameters, with one accelerometer positioned between both sacral tuberosities, included speed, stride frequency and length, regularity, dorsoventral, longitudinal, mediolateral and total accelerometric activities, relative force index and dorsoventral, longitudinal and mediolateral parts of the accelerometric activities. Head height above the ground (cm) and subjective ataxia degree were also measured. Baseline values (−15 min) and values measured 5 and 15 min after the injection and then every 15 min for a period of 2 h were obtained. Results There was a negative and strong correlation between head height above the ground and ataxia degree (Pearson r = −0.78, p < 0.001), particularly during the first 45 min. A significant correlation was found between head height above the ground and almost all accelerometric parameters. This correlation was very strong with stride frequency, regularity and dorsoventral and total accelerometric activities in both cases, but for ataxia, also with total accelerometric activity. Main limitations Experimental conditions may not represent real clinical situations. Conclusions Stride frequency and regularity are the most reliable parameters to determine degree of sedation and are related to the sedation produced. Ataxia should not be considered a separate property of sedation and does not need to be assessed separately to the depth of sedation
dc.description.departmentDepto. de Medicina y Cirugía Animal
dc.description.facultyFac. de Veterinaria
dc.description.refereedTRUE
dc.description.statuspub
dc.identifier.citationIzquierdo-Moreno, J., de Paz, M. I., Manso-Díaz, G., Villalba-Orero, M., & López-Sanromán, J. (2024). Correlation between kinematic parameters, ataxia and ground-to-lip distance in detomidine sedated horses. Equine veterinary journal, 10.1111/evj.14207. Advance online publication. https://doi.org/10.1111/evj.14207
dc.identifier.doi10.1111/evj.14207
dc.identifier.essn2042-3306
dc.identifier.officialurlhttps://doi.org/10.1111/evj.14207
dc.identifier.pmid39140154
dc.identifier.urihttps://hdl.handle.net/20.500.14352/107854
dc.journal.titleEquine Veterinary Journal
dc.language.isoeng
dc.page.final8
dc.page.initial1
dc.publisherWiley
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalen
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.cdu636.1
dc.subject.keywordAccelerometry
dc.subject.keywordAnaesthesia
dc.subject.keywordAtaxia
dc.subject.keywordGait analysis
dc.subject.keywordHorse
dc.subject.keywordSedation
dc.subject.ucmVeterinaria
dc.subject.unesco3109 Ciencias Veterinarias
dc.titleCorrelation between kinematic parameters, ataxia and ground-to-lip distance in detomidine sedated horses
dc.typejournal article
dc.type.hasVersionAM
dspace.entity.typePublication
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