Intracellular Silicon Chips in Living Cells
Loading...
Official URL
Full text at PDC
Publication date
2010
Advisors (or tutors)
Editors
Journal Title
Journal ISSN
Volume Title
Publisher
Willey
Citation
Gómez-Martínez R, Vázquez P, Duch M, Muriano A, Pinacho D, Sanvicens N, Sánchez-Baeza F, Boya P, de la Rosa EJ, Esteve J, Suárez T, Plaza JA. Intracellular silicon chips in living cells. Small. 2010 Feb 22;6(4):499-502. doi: 10.1002/smll.200901041.
Abstract
Silicon-based chips offer high flexibility and versatility as they are based on semiconductor and MEMS technology. They can be top-down fabricated with well-controlled shape and size. Silicon microchips can be internalized into eukaryotic cells (see image) without interfering with cell viability. Engineered intracellular chips with different biomolecules attached to the surface can be used as intracellular sensors.