EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology
| dc.contributor.author | Reche Gallardo, Pedro Antonio | |
| dc.contributor.author | Zhang, Hong | |
| dc.contributor.author | Glutting, John-Paul | |
| dc.contributor.author | Reinherz, Ellis L | |
| dc.date.accessioned | 2023-06-20T09:48:17Z | |
| dc.date.available | 2023-06-20T09:48:17Z | |
| dc.date.issued | 2005 | |
| dc.description.abstract | EPIMHC is a relational database of MHC-binding peptides and T cell epitopes that are observed in real proteins. Currently, the database contains 4867 distinct peptide sequences from various sources, including 84 tumor-associated antigens. The EPIMHC database is accessible through a web server that has been designed to facilitate research in computational vaccinology. Importantly, peptides resulting from a query can be selected to derive specific motif-matrices. Subsequently, these motif-matrices can be used in combination with a dynamic algorithm for predicting MHC-binding peptides from user-provided protein queries. AVAILABILITY: The EPIMHC database server is hosted by the Dana-Farber Cancer Institute at the site http://immunax.dfci.harvard.edu/bioinformatics/epimhc/ | |
| dc.description.department | Depto. de Inmunología, Oftalmología y ORL | |
| dc.description.faculty | Fac. de Medicina | |
| dc.description.refereed | TRUE | |
| dc.description.status | pub | |
| dc.eprint.id | https://eprints.ucm.es/id/eprint/9332 | |
| dc.identifier.doi | 10.1093/bioinformatics/bti269 | |
| dc.identifier.issn | 1367-4803 | |
| dc.identifier.officialurl | http://bioinformatics.oxfordjournals.org/content/21/9/2140.abstract | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14352/50385 | |
| dc.issue.number | 9 | |
| dc.journal.title | Bioinformatics (Oxford, England) | |
| dc.language.iso | eng | |
| dc.page.final | 2141 | |
| dc.page.initial | 2140 | |
| dc.publisher | Oxford University Press | |
| dc.rights.accessRights | open access | |
| dc.subject.cdu | 612.017 | |
| dc.subject.cdu | 57:004 | |
| dc.subject.ucm | Inmunología | |
| dc.subject.ucm | Biología molecular (Biología) | |
| dc.subject.ucm | Bioinformática | |
| dc.subject.unesco | 2412 Inmunología | |
| dc.subject.unesco | 2415 Biología Molecular | |
| dc.title | EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology | |
| dc.type | journal article | |
| dc.volume.number | 21 | |
| dspace.entity.type | Publication | |
| relation.isAuthorOfPublication | 372eb700-f6f8-4156-80f5-b8f7c9edafe1 | |
| relation.isAuthorOfPublication.latestForDiscovery | 372eb700-f6f8-4156-80f5-b8f7c9edafe1 |
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