Biomechanical Stability of Three Intraocular Lenses With Different Haptic Designs: In Silico and In Vivo Evaluation

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dc.contributor.authorLaura Remón
dc.contributor.authorIulen Cabeza-Gil
dc.contributor.authorBegoña Calvo
dc.contributor.authorFrancisco Poyales
dc.contributor.authorNuria Garzón
dc.contributor.authorGarzón Jiménez, Nuria
dc.date.accessioned2023-11-16T19:08:18Z
dc.date.available2023-11-16T19:08:18Z
dc.date.issued2020-07-13
dc.description.abstractPurpose: To assess the biomechanical stability of three different marketed intraocular lenses (IOLs) with different haptic designs (four-loop IOL [Micro F FineVision model] and double C-loop IOL [POD F and POD FT models], all manufactured by PhysIOL), in silico (computer simulation) and in vivo (in the context of lens surgery). Methods: An in silico simulation investigation was performed using finite element modeling (FEM) software to reproduce the compression test defined by the International Organization for Standardization and in vivo implantation in patients in the context of lens surgery was evaluated 1 day and 3 months postoperatively. IOL decentration and rotation were tested. In addition, the stress and strains were analyzed with the finite element method. Results: In the in silico evaluation, the compression force for the POD F IOL was slightly lower than for the POD FT IOL and Micro F IOL for all compression diameters. The axial displacement was maximum for the POD FT IOL and the tilt, rotation, and lateral decentration were substantially lower than the acceptable tolerance limits established in ISO 11979-2. In the in vivo evaluation, a total of 45 eyes from 45 patients were selected, 15 eyes for each IOL model under assessment. Statistically significant differences were found between the Micro F and POD F IOLs for lateral decentration in the x-direction (in absolute value) at 3 months postoperatively (P = .03). Conclusions: Although statistically significant differences have been found when comparing the displacement, tilt, and rotation between the different lenses, these differences cannot be considered clinically relevant, which would suggest that all three IOL models yield excellent stability in those terms. FEM appears to be a powerful tool for numerical studies of the biomechanical properties of IOLs. [J Refract Surg. 2020;36(9):617-624.]
dc.description.departmentDepto. de Optometría y Visión
dc.description.facultyFac. de Óptica y Optometría
dc.description.refereedTRUE
dc.description.sponsorshipMinisterio de Economía y Competitividad de España
dc.description.sponsorshipFondos FEDER
dc.description.statuspub
dc.identifier.citationRemón L, Cabeza-Gil I, Calvo B, Poyales F, Garzón N. Biomechanical Stability of Three Intraocular Lenses With Different Haptic Designs: In Silico and In Vivo Evaluation. J Refract Surg. 2020 Sep 1;36(9):617-624
dc.identifier.doi10.3928/1081597x-20200713-02
dc.identifier.essn1938-2391
dc.identifier.issn1081-597X
dc.identifier.officialurlhttps://doi.org/10.3928/1081597X-20200713-02
dc.identifier.urihttps://hdl.handle.net/20.500.14352/88771
dc.issue.number9
dc.journal.titleJournal of Refractive Surgery
dc.language.isoeng
dc.page.final624
dc.page.initial617
dc.publisherSlack incorporated
dc.relation.projectIDinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/DPI2017-84047-R/ES/MODELADO PERSONALIZADO IN-SILICO DEL GLOBO OCULAR. AYUDA AL DISEÑO Y PLANIFICACION DE TRATAMIENTOS OFTALMOLOGICOS/
dc.rights.accessRightsrestricted access
dc.subject.cdu617.7-089.243
dc.subject.cdu681.73
dc.subject.keywordIOLs, Intraocular lenses; Computer Simulation; Eye surgery; Biomechanical stability
dc.subject.ucmÓptica y optometría
dc.subject.ucmOftalmología
dc.subject.ucmMateriales ópticos
dc.subject.unesco2209.15 Optometría
dc.subject.unesco3311.09 Lentes
dc.subject.unesco1203.26 Simulación
dc.subject.unesco3213 Cirugía
dc.titleBiomechanical Stability of Three Intraocular Lenses With Different Haptic Designs: In Silico and In Vivo Evaluation
dc.typejournal article
dc.type.hasVersionAM
dc.volume.number36
dspace.entity.typePublication
relation.isAuthorOfPublication367ce491-287f-4b2a-ba6a-870a393c5609
relation.isAuthorOfPublication.latestForDiscovery367ce491-287f-4b2a-ba6a-870a393c5609
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