Blue filters protect the retina from light damage but do not reduce functionality of photosensitive ganglion cells.

Abstract

PURPOSE: To study de effect of blue filters of specific wavelengths on ERG responses and circadian activity (CA) in the pigmented and albino mouse. Blue light has been shown to induce a retinal damage in the albino mice, which determines significant decrease of retinal light reponses. As an attempt to reduce light damage, we have tested the protective effect of light filters in the 400-500 wavelength range on light sensitivity. However, maximum sensitivity of ipRGCs also range in the blue spectrum. Since ipRGC seem to be important for the animal circadian activity, we wonder if blue filters myy also affect the circadian activity in animal exposed to light damage.