Caracterización del órgano yuxtaoral
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2024
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26/04/2023
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Universidad Complutense de Madrid
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Abstract
El órgano yuxtaoral (JOO) es una estructura constante, bilateral, que se sitúa en la región infratemporal. A pesar de haber sido descrito hace 137 años por Johan Henrik Chievitz, son muy escasos los trabajos que se han llevado a cabo para estudiarlo, por lo que algunos aspectos de su morfología, organización y función aún hoy en día no están totalmente aclarados. El parénquima del JOO deriva del epitelio de la boca primitiva, del que se desconecta durante el desarrollo. En ratas, el mesénquima que constituye su estroma parece derivar de las células de la cresta neural. Además, está localizado en la región de los músculos masticadores y está −desde el comienzo de su desarrollo− en relación con el nervio bucal, del que recibe inervación. En adultos, tiene forma fusiforme de 7-17 mm de longitud y 2 mm de grosor, aproximadamente. Su aspecto macroscópico es el de una fibra conectiva o un filete nervioso. Su extremo posterior se dispone entre el músculo pterigoideo medial y el rafepterigo mandibular. Su extremo anterior, entre la mandíbula y el músculo buccinador, caudal a la desembocadura del conducto parotídeo. Está inervado por 2-4 filetes nerviosos del nervio bucal. A pesar de esta exhaustiva descripción hay confusión en su localización, ya que la mayoría de los estudios se han realizado sobre piezas de biopsias de la región...
The juxtaoral organ (JOO) is a constant, bilateral structure located in the infratemporal region. Although it was described 137 years ago by Johan Henrik Chievitz, little work has been done to study it in detail, so that some aspects of its morphology, organization and function are still not fully elucidated. The parenchyma of the JOO is derived from the epithelium of the primitive mouth, from which it is disconnected during development. In rats, the mesenchyme that constitutes its stroma appears to be derived from neural crest cells. Furthermore, it is located in the region of the masticatory muscles and is - from the beginning of its development - in relation to the buccal nerve, from which it receives innervation. In adults, it is fusiform in shape, approximately 7-17 mm long and 2 mm thick. Its macroscopic appearance is that of a connective fiber or nerve fillet. Its posterior end lies between the medial pterygoid muscle and the pterygomandibular raphe. Its anterior end, between the mandible and the buccinator muscle, caudal to the mouth of the parotid duct. It is innervated by 2-4 nerve fibers of the buccal nerve. Despite this exhaustive description, there is confusion as to its location, as most studies have been performed on biopsy specimens from the region...
The juxtaoral organ (JOO) is a constant, bilateral structure located in the infratemporal region. Although it was described 137 years ago by Johan Henrik Chievitz, little work has been done to study it in detail, so that some aspects of its morphology, organization and function are still not fully elucidated. The parenchyma of the JOO is derived from the epithelium of the primitive mouth, from which it is disconnected during development. In rats, the mesenchyme that constitutes its stroma appears to be derived from neural crest cells. Furthermore, it is located in the region of the masticatory muscles and is - from the beginning of its development - in relation to the buccal nerve, from which it receives innervation. In adults, it is fusiform in shape, approximately 7-17 mm long and 2 mm thick. Its macroscopic appearance is that of a connective fiber or nerve fillet. Its posterior end lies between the medial pterygoid muscle and the pterygomandibular raphe. Its anterior end, between the mandible and the buccinator muscle, caudal to the mouth of the parotid duct. It is innervated by 2-4 nerve fibers of the buccal nerve. Despite this exhaustive description, there is confusion as to its location, as most studies have been performed on biopsy specimens from the region...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, leída el 26-04-2023