A cephalometric method to diagnosis the craniovertebral junction abnormalities in osteogenesis imperfecta patients

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dc.contributor.authorRios Rodenas, Mercedes
dc.contributor.authorNova García, Manuel Joaquín De
dc.contributor.authorGutiérrez Díez, Mª Pilar
dc.contributor.authorFeijoo García, Gonzalo
dc.contributor.authorMourelle Martínez, Rosa
dc.contributor.authorGarcilazo Ambriz, Mario
dc.contributor.authorOrtega Aranegui, Ricardo
dc.date.accessioned2024-03-14T10:06:05Z
dc.date.available2024-03-14T10:06:05Z
dc.date.issued2015-02-01
dc.description.abstractOsteogenesis imperfecta (OI) is a hereditary bone fragility disorder that in most patients is caused by mutations affecting collagen type I. Their typical oral and craneofacial characteristics (Dentinogenesis imperfecta type I and class III malocclusion), involve the dentist in the multidisciplinary team that treat these patients. It is usual to perform lateral skull radiographs for the orthodontic diagnosis. In addition, this radiograph is useful to analyse the junctional area between skull base and spine, that could be damaged in OI. Pathology in the craneovertebral junction (CVJ) is a serious complication of OI with a prevalence ranging from rare to 37%. To diagnosis early skull base anomalies in these patients, previously the neurological symptoms have been appear, we make a simple cephalometric analysis of the CVJ. This method has four measurements and one angle. Once we calculate the values of the OI patient, we compare the result with the mean and the standard deviations of an age-appropriate average in healthy controls. If the patient has a result more than 2,5 SDs above the age appropriate average in healthy controls, we should to refer the patient to his/her pediatrician or neurologist. These doctors have to consider acquiring another diagnostic images to be used to determine cranial base measurements with more reliability. Thereby, dentists who treat these patients, must be aware of the normal radiological anatomy of the cervical spine on the lateral cephalogram.
dc.description.departmentDepto. de Especialidades Clínicas Odontológicas
dc.description.facultyFac. de Odontología
dc.description.refereedTRUE
dc.description.sponsorshipThis work was supported by Grant No. AP123942013 from the Mutua Madrileña Foundation for Medical Research, Madrid
dc.description.statuspub
dc.identifier.citationRíos-Rodenas M, de Nova J, Gutiérrez-Díez MP, Feijóo G, Mourelle MR, Garcilazo M, Ortega-Aranegui R. A cephalometric method to diagnosis the craniovertebral junction abnormalities in osteogenesis imperfecta patients. J Clin Exp Dent. 2015 Feb 1;7(1):e153-8
dc.identifier.doi10.4317/jced.52126
dc.identifier.essn1989-5488
dc.identifier.issn1988-8708
dc.identifier.officialurlhttp://www.medicinaoral.com/odo/volumenes/v7i1/jcedv7i1p153.pdf
dc.identifier.pmid25810828
dc.identifier.urihttps://hdl.handle.net/20.500.14352/102215
dc.issue.number1
dc.journal.titleJournal of Clinical Experimental Dentistry
dc.language.isoeng
dc.page.finale158
dc.page.initiale153
dc.publisherMedicina Oral
dc.rights.accessRightsopen access
dc.subject.cdu616.314
dc.subject.cdu616.71
dc.subject.cdu572.72
dc.subject.keywordosteogenesis imperfecta
dc.subject.keywordcraniovertebral junction
dc.subject.keywordcephalometric
dc.subject.ucmCiencias Biomédicas
dc.subject.ucmOdontología (Odontología)
dc.subject.ucmOdontología (Medicina)
dc.subject.ucmDiagnóstico por imagen y medicina nuclear
dc.subject.unesco32 Ciencias Médicas
dc.subject.unesco3207.14 Osteopatología
dc.titleA cephalometric method to diagnosis the craniovertebral junction abnormalities in osteogenesis imperfecta patients
dc.typejournal article
dc.type.hasVersionVoR
dc.volume.number7
dspace.entity.typePublication
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