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Phosphorylation of FOXO Proteins as a Key Mechanism to Regulate Their Activity

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dc.book.titleFOXO Transcription Factors: Methods and Protocols
dc.contributor.authorOrea-Soufi, Alba
dc.contributor.authorDávila, David
dc.contributor.authorSalazar Roa, María
dc.contributor.authorLorente Pérez, María Del Mar
dc.contributor.authorVelasco Díez, Guillermo
dc.contributor.editorLink, Wolfgang
dc.date.accessioned2023-06-17T14:17:45Z
dc.date.available2023-06-17T14:17:45Z
dc.date.issued2019
dc.description.abstractPhosphorylation of FOXO transcription factors is one of the key mechanisms involved in the regulation of the activity, nucleo-cytosolic shuttling, and stability of this family of proteins. Here, we describe several experimental approaches allowing analysis of changes in the phosphorylation of these proteins upon exposure to different stimuli.
dc.description.departmentSección Deptal. de Bioquímica y Biología Molecular (Biológicas)
dc.description.facultyFac. de Ciencias Biológicas
dc.description.refereedTRUE
dc.description.sponsorshipUnión Europea. H2020
dc.description.sponsorshipMinisterio de Ciencia e Innovación (MICINN)
dc.description.sponsorshipInstituto de Salud Carlos III (ISCIII)
dc.description.sponsorshipFondo Europeo de Desarrollo Regional (FEDER)
dc.description.sponsorshipVoices Against Brain Cancer
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/56792
dc.identifier.doi10.1007/978-1-4939-8900-3
dc.identifier.isbn978-1-4939-8900-3
dc.identifier.officialurlhttps://link.springer.com/protocol/10.1007%2F978-1-4939-8900-3_5
dc.identifier.urihttps://hdl.handle.net/20.500.14352/14005
dc.issue.number1890
dc.language.isoeng
dc.page.final59
dc.page.initial51
dc.page.total266
dc.publication.placeMadrid
dc.publisherSpringer
dc.relation.ispartofseriesMethods in Molecular Biology
dc.relation.projectIDTRAIN (721532)
dc.relation.projectIDPlan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016 (PI15/00339)
dc.rights.accessRightsrestricted access
dc.subject.cdu577.1
dc.subject.cdu577.2
dc.subject.keywordFOXO phosphorylation
dc.subject.keywordWestern blot
dc.subject.keywordImmunofluorescence
dc.subject.keywordcell fractioning
dc.subject.ucmBiología molecular (Biología)
dc.subject.ucmBioquímica (Biología)
dc.subject.unesco2415 Biología Molecular
dc.subject.unesco2302 Bioquímica
dc.titlePhosphorylation of FOXO Proteins as a Key Mechanism to Regulate Their Activity
dc.typebook part
dspace.entity.typePublication
relation.isAuthorOfPublication85418c2e-51eb-43c9-a82f-05a96903381f
relation.isAuthorOfPublication974345b1-6b30-49ae-9724-2e4714f80000
relation.isAuthorOfPublication4a33b5e2-6540-4927-ab0d-bc37f5cd8b5b
relation.isAuthorOfPublication.latestForDiscovery85418c2e-51eb-43c9-a82f-05a96903381f

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