Ácidos grasos de cadena corta y esclerosis múltiple : asociación de los niveles de acetato, propionato y butirato con la progresión y actividad de la enfermedad y con el sistema inmune de los pacientes
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2026
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12/04/2024
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Universidad Complutense de Madrid
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Abstract
La esclerosis múltiple (EM) es una enfermedad con características autoinmunes que afecta al sistema nervioso central. En los últimos años, se ha observado una alteración en la composición de la microbiota intestinal en pacientes de EM con respecto a población sana. Los ácidos grasos de cadena corta (AGCC) son metabolitos producidos por las bacterias intestinales que se han relacionado con diferentes mecanismos fisiológicos del organismo humano, de entre ellos parecen participar en la regulación del sistema inmunológico...
Multiple sclerosis (MS) is a disease with autoimmune characteristics that affects the central nervous system. In recent years, an alteration in the composition of the intestinal microbiota has been observed in patients with MS with respect to the healthy population. Short-chain fatty acids (SCFA) are metabolites produced by intestinal bacteria that have been related to different physiological mechanisms of the human organism, among them they seem to participate in the regulation of the immune system...
Multiple sclerosis (MS) is a disease with autoimmune characteristics that affects the central nervous system. In recent years, an alteration in the composition of the intestinal microbiota has been observed in patients with MS with respect to the healthy population. Short-chain fatty acids (SCFA) are metabolites produced by intestinal bacteria that have been related to different physiological mechanisms of the human organism, among them they seem to participate in the regulation of the immune system...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, leída el 12-04-2024







