Publication: Valoración de la eficacia del gel tópico mucorepair Lacer ren la disminución de la inflamación, el dolor, el trismo y la mejora de la cicatrización tras la extracción de los terceros molares. Estudio controlado aleatorizado a boca partida.
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2021
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Abstract
Introducción
La extracción del tercer molar es el acto quirúrgico más frecuente en la práctica habitual en cirugía oral y maxilofacial. Sin embargo, la prevalencia de complicaciones intra y postoperatorias es alta, de los cuales el 81% de las complicaciones ocurren en el postoperatorio. Para reducir y aliviar las complicaciones postoperatorias (dolor, inflamación, trismo y alveolitis), se han valorado diferentes medicamentos, sobre todo antisépticos tópicos.
Material y método: Se realizó un ensayo clínico aleatorizado a boca partida, en el que tras la extracción, se colocó el producto experimental el l gel tópico Mucorepair en uno de los alveolos, y en el alveolo contra lateral el gel placebo. Se incluyó a 20 pacientes que fueron intervenidos de manera bilateral (40 alveolos), con el objetivo evaluar y comparar el efecto del gel tópico Mucorepair con un placebo frente al dolor, la inflamación, el trismo y la cicatrización postquirúrgica tras la extracción de los terceros molares.
Resultados:Un paciente sufrió una alveolitis en el GC(5%) y ninguno en el GE(0%), pero no se encontró diferencia estadísticamente significativa ( p = 0,500). Desde el día 0 hasta el día 7, el trismo y la inflamación fueron menos pronunciados en el GE, y la cicatrización de la herida se consideró "buena" en el 55% para el GC y el 90% para el GE ( p <0,028). Las puntuaciones medias de la EVA durante los siete días posoperatorios fueron estadísticamente más bajas en el grupo experimental (0,30 ± 0,97) en comparación con el grupo de placebo (1,55 ± 2,03) ( p = 0,001). El consumo de analgésicos durante las primeras 72 horas también fue estadísticamente menor en el GE (0,15 ± 0,67) en comparación con el GC (0,20 ± 0,61) ( p = 1,000). Conclusiones: El uso de un gel MucorepairÒ que contiene Asiaticósido, ácido hialurónico y enoxolona parece reducir significativamente el dolor postoperatorio y logra una buena cicatrización. Sin embargo, ambos grupos presentaron similar grado de inflamación y capacidad de apertura bucal.
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Trabajo de Fin de Máster en Ciencias Odontológicas, Facultad de Odontología UCM, Departamento de Especialidades Clínicas Odontológicas, Curso 2020/2021
UCM subjects
Unesco subjects
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