Diagnostics Strategies with Electrochemical Affinity Biosensors Using Carbon Nanomaterials as Electrode Modifiers

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dc.contributor.authorCampuzano Ruiz, Susana
dc.contributor.authorYáñez-Sedeño Orive, Paloma
dc.contributor.authorPingarrón Carrazón, José Manuel
dc.date.accessioned2023-06-18T00:02:35Z
dc.date.available2023-06-18T00:02:35Z
dc.date.issued2016-12-26
dc.description.abstractEarly diagnosis is often the key to successful patient treatment and survival. The identification of various disease signaling biomarkers which reliably reflect normal and disease states in humans in biological fluids explain the burgeoning research field in developing new methodologies able to determine the target biomarkers in complex biological samples with the required sensitivity and selectivity and in a simple and rapid way. The unique advantages offered by electrochemical sensors together with the availability of high affinity and specific bioreceptors and their great capabilities in terms of sensitivity and stability imparted by nanostructuring the electrode surface with different carbon nanomaterials have led to the development of new electrochemical biosensing strategies that have flourished as interesting alternatives to conventional methodologies for clinical diagnostics. This paper briefly reviews the advantages of using carbon nanostructures and their hybrid nanocomposites as electrode modifiers to construct efficient electrochemical sensing platforms for diagnosis. The review provides an updated overview of some selected examples involving attractive amplification and biosensing approaches which have been applied to the determination of relevant genetic and protein diagnostics biomarkers.
dc.description.departmentDepto. de Química Analítica
dc.description.facultyFac. de Ciencias Químicas
dc.description.refereedTRUE
dc.description.sponsorshipMinisterio de Economía y Competitividad (MINECO)
dc.description.sponsorshipComunidad de Madrid
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/66272
dc.identifier.doi10.3390/diagnostics7010002
dc.identifier.issn2075-4418
dc.identifier.officialurlhttps://doi.org/10.3390/diagnostics7010002
dc.identifier.relatedurlhttps://www.mdpi.com/2075-4418/7/1/2
dc.identifier.urihttps://hdl.handle.net/20.500.14352/19183
dc.issue.number1
dc.journal.titleDiagnostics
dc.language.isoeng
dc.page.initial2
dc.publisherMDPI
dc.relation.projectIDCTQ2015-70023-R y CTQ2015-64402-C2-1-R
dc.relation.projectIDNANOAVANSENS-CM (S2013/MT3029)
dc.rightsAtribución 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/es/
dc.subject.keywordelectrochemical affinity biosensors
dc.subject.keyworddiagnosis
dc.subject.keywordcarbon nanostructures
dc.subject.keywordgraphene
dc.subject.keywordoligonucleotides
dc.subject.keywordproteins
dc.subject.keywordantibodies
dc.subject.ucmQuímica analítica (Química)
dc.subject.unesco2301 Química Analítica
dc.titleDiagnostics Strategies with Electrochemical Affinity Biosensors Using Carbon Nanomaterials as Electrode Modifiers
dc.typejournal article
dc.volume.number7
dspace.entity.typePublication
relation.isAuthorOfPublication6945fb1e-9c48-459d-b994-e64328c3e79b
relation.isAuthorOfPublication06ab2fa0-2b2d-4b58-80ed-82f9cc767175
relation.isAuthorOfPublication8808f99c-5f56-4562-839a-517626c76dad
relation.isAuthorOfPublication.latestForDiscovery6945fb1e-9c48-459d-b994-e64328c3e79b
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