Further Advances in Atrial Fibrillation Research: A Metabolomic Perspective

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dc.contributor.authorArbeloa Gómez, Laura
dc.contributor.authorÁlvarez Vidal, Jaime
dc.contributor.authorIzquierdo García, José Luis
dc.date.accessioned2023-06-22T11:04:57Z
dc.date.available2023-06-22T11:04:57Z
dc.date.issued2022-03-21
dc.description.abstractAtrial fibrillation involves an important type of heart arrhythmia caused by a lack of control in the electrical signals that arrive in the heart, produce an irregular auricular contraction, and induce blood clotting, which finally can lead to stroke. Atrial fibrillation presents some specific characteristics, but it has been treated and prevented using conventional methods similar to those applied to other cardiovascular diseases. However, due to the influence of this pathology on the mortality caused by cerebrovascular accidents, further studies on the molecular mechanism of atrial fibrillation are required. Our aim here is provide a compressive review of the use of metabolomics on this condition, from the study of the metabolic profile of plasma to the development of animal models. In summary, most of the reported studies highlighted alterations in the energetic pathways related to the development of the condition.
dc.description.departmentDepto. de Química en Ciencias Farmacéuticas
dc.description.facultyFac. de Farmacia
dc.description.refereedTRUE
dc.description.sponsorshipUnión Europea. Horizonte 2020
dc.description.sponsorshipMinisterio de Ciencia e Innovación (MICINN)
dc.description.sponsorshipComunidad de Madrid
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/74846
dc.identifier.doi10.3390/app12063201
dc.identifier.issn2076-3417
dc.identifier.officialurlhttps://doi.org/10.3390/app12063201
dc.identifier.relatedurlhttps://www.mdpi.com/2076-3417/12/6/3201/htm
dc.identifier.urihttps://hdl.handle.net/20.500.14352/72084
dc.issue.number6
dc.journal.titleApplied Sciences
dc.language.isoeng
dc.page.initial3201
dc.publisherMPDI
dc.relation.projectIDINNOVA4TB (823854)
dc.relation.projectIDPID2019-10656RJ-I00
dc.relation.projectIDB2017/BMD3875
dc.rightsAtribución 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/es/
dc.subject.keywordatrial fibrillation
dc.subject.keywordheart arrhythmia
dc.subject.keywordmetabolomics
dc.subject.keywordmetabolic profile
dc.subject.ucmCardiología
dc.subject.ucmEndocrinología
dc.subject.unesco3205.01 Cardiología
dc.subject.unesco3205.02 Endocrinología
dc.titleFurther Advances in Atrial Fibrillation Research: A Metabolomic Perspective
dc.typejournal article
dc.volume.number12
dspace.entity.typePublication
relation.isAuthorOfPublication43d1cf74-cf38-4c81-834f-306e6d1c9b4e
relation.isAuthorOfPublication.latestForDiscovery43d1cf74-cf38-4c81-834f-306e6d1c9b4e
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